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5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat.

artículo científico publicado en 2016

A Bivalent Ligand Targeting the Putative Mu Opioid Receptor and Chemokine Receptor CCR5 Heterodimers: Binding Affinity versus Functional Activities

artículo científico publicado en 2013

A novel bivalent HIV-1 entry inhibitor reveals fundamental differences in CCR5-μ-opioid receptor interactions between human astroglia and microglia

artículo científico publicado el 10 de septiembre de 2013

Androgen action in fetal mouse spinal cord cultures: metabolic and morphologic aspects

scientific article published on 01 March 1987

Apoptotic death of striatal neurons induced by human immunodeficiency virus-1 Tat and gp120: Differential involvement of caspase-3 and endonuclease G

artículo científico publicado en 2004

Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain

artículo científico publicado en 2013

Characterization of cell-cell junction changes associated with the formation of a strong endothelial barrier.

artículo científico publicado en 2018

Characterization of opioid-dependent glial development in dissociated and organotypic cultures of mouse central nervous system: critical periods and target specificity

artículo científico publicado el 21 de octubre de 1991

Chronic HIV-1 Tat and HIV reduce Rbfox3/NeuN: evidence for sex-related effects

artículo científico publicado en 2015

Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging

artículo científico

Co-localization of proenkephalin mRNA using cRNA probes and a cell-type-specific immunocytochemical marker for intact astrocytes in vitro

artículo científico publicado el 1 de febrero de 1991

Cross-talk between microglia and neurons regulates HIV latency

artículo científico publicado en 2019

Differential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types

artículo científico publicado en 2012

Differential expression of the alternatively spliced OPRM1 isoform μ-opioid receptor-1K in HIV-infected individuals

scientific article published on January 2014

Diversity and developmental regulation of extraocular muscle: progress and prospects

artículo científico publicado en 1993

Effects of HIV-1 Tat and Methamphetamine on Blood-Brain Barrier Integrity and Function In Vitro

artículo científico publicado en 2017

Effects of HIV-1 Tat on enteric neuropathogenesis.

artículo científico publicado en 2014

Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior

artículo científico publicado en 2013

Effects of chronic expression of the HIV-induced protein, transactivator of transcription, on circadian activity rhythms in mice, with or without morphine

artículo científico publicado en 2008

Effects of thyroidectomy and season on the external granular layer of the cerebellum in metamorphosing bullfrog tadpoles (Rana catesbeiana).

artículo científico publicado en 1983

Endogenous opioid system in developing normal and jimpy oligodendrocytes: ? and ? opioid receptors mediate differential mitogenic and growth responses

artículo científico publicado el 1 de febrero de 1998

Endogenous opioids regulate dendritic growth and spine formation in developing rat brain

artículo científico publicado en 1987

Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine

artículo científico publicado en 2001

Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death

artículo científico publicado en 2011

GSK3β-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity

artículo científico publicado en 2015

Glial modulators as potential treatments of psychostimulant abuse

artículo científico publicado en 2014

HIV-1 Tat and Morphine Differentially Disrupt Pyramidal Cell Structure and Function and Spatial Learning in Hippocampal Area CA1: Continuous versus Interrupted Morphine Exposure

artículo científico publicado en 2021

HIV-1 Tat and opiate-induced changes in astrocytes promote chemotaxis of microglia through the expression of MCP-1 and alternative chemokines

artículo científico publicado en 2006

HIV-1 Tat disrupts blood-brain barrier integrity and increases phagocytic perivascular macrophages and microglia in the dorsal striatum of transgenic mice

artículo científico publicado en 2017

HIV-1 alters neural and glial progenitor cell dynamics in the central nervous system: coordinated response to opiates during maturation

artículo científico publicado en 2012

HIV-1 coinfection and morphine coexposure severely dysregulate hepatitis C virus-induced hepatic proinflammatory cytokine release and free radical production: increased pathogenesis coincides with uncoordinated host defenses

artículo científico publicado en 2011

HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuse

artículo científico publicado en 2006

HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase.

artículo científico publicado en 2015

Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine

artículo científico publicado en 2014

Impact of opiate-HIV-1 interactions on neurotoxic signaling

artículo científico publicado en 2006

Interactions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors

artículo científico publicado en 2014

Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.

artículo científico publicado en 2014

Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons

artículo científico publicado en 2010

Lateralized response of dynorphin a peptide levels after traumatic brain injury

artículo científico publicado en 2012

Molecular basis for interactions of HIV and drugs of abuse.

artículo científico publicado en 2002

Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.

artículo científico publicado en 2015

Morphine and gp120 toxic interactions in striatal neurons are dependent on HIV-1 strain

artículo científico publicado en 2011

Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 Tat transgenic mice

scientific article published on October 2008

Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice.

artículo científico publicado en 2012

Morphine enhances HIV-1SF162-mediated neuron death and delays recovery of injured neurites

artículo científico publicado en 2014

Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcription

artículo científico publicado en 2008

Morphine potentiates neurodegenerative effects of HIV-1 Tat through actions at μ-opioid receptor-expressing glia

artículo científico publicado en 2011

Morphine regulates DNA synthesis in rat cerebellar neuroblasts in vitro

artículo científico publicado el 18 de diciembre de 1992

Neurotoxicity and dysfunction of dopaminergic systems associated with AIDS dementia

artículo científico publicado en 2000

Oligodendrocytes Are Targets of HIV-1 Tat: NMDA and AMPA Receptor-Mediated Effects on Survival and Development.

artículo científico publicado en 2015

Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca²⁺]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity.

artículo científico publicado en 2014

Opiate drug use and the pathophysiology of neuroAIDS.

artículo científico publicado en 2012

Opioid and neuroHIV Comorbidity - Current and Future Perspectives

scientific article published on 02 September 2020

Opioid-related changes in nociceptive threshold and in tissue levels of enkephalins after target disruption of the gene for neutral endopeptidase (EC 3.4.24.11) in mice

artículo científico publicado el 26 de septiembre de 1997

Opioids Disrupt Ca2+Homeostasis and Induce Carbonyl Oxyradical Production in Mouse Astrocytesin Vitro:Transient Increases and Adaptation to Sustained Exposure

artículo científico publicado el 1 de mayo de 1998

Opposing actions of the EGF family and opioids: heparin binding-epidermal growth factor (HB-EGF) protects mouse cerebellar neuroblasts against the antiproliferative effect of morphine

artículo científico publicado el 31 de agosto de 1998

Pathobiology of dynorphins in trauma and disease

artículo científico publicado en 2005

Preferential vulnerability of astroglia and glial precursors to combined opioid and HIV-1 Tat exposure in vitro.

artículo científico publicado en 2004

Productive infection of human neural progenitor cells by R5 tropic HIV-1: opiate co-exposure heightens infectivity and functional vulnerability

scientific article published on 17 January 2017

Prodynorphin mutations cause the neurodegenerative disorder spinocerebellar ataxia type 23.

artículo científico publicado en 2010

Prodynorphin storage and processing in axon terminals and dendrites

artículo científico publicado en 2006

Purkinje cell maturation in the frog cerebellum during thyroxine-induced metamorphosis

scientific article published on 01 January 1984

Rat nucleus accumbens core astrocytes modulate reward and the motivation to self-administer ethanol after abstinence

artículo científico publicado en 2014

Reduced intraepidermal nerve fibre density, glial activation, and sensory changes in HIV type-1 Tat-expressing female mice: involvement of Tat during early stages of HIV-associated painful sensory neuropathy.

artículo científico publicado en 2018

Regional heterogeneity and diversity in cytokine and chemokine production by astroglia: differential responses to HIV-1 Tat, gp120, and morphine revealed by multiplex analysis

artículo científico publicado en 2010

Regional, developmental, and cell cycle-dependent differences in ?, ?, and ?-opioid receptor expression among cultured mouse astrocytes

artículo científico publicado el 1 de marzo de 1998

Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice

artículo científico publicado en 2021

Secretoneurin promotes pertussis toxin‐sensitive neurite outgrowth in cerebellar granule cells

artículo científico publicado el 1 de mayo de 2003

Selective Vulnerability of Striatal D2 versus D1 Dopamine Receptor-Expressing Medium Spiny Neurons in HIV-1 Tat Transgenic Male Mice.

artículo científico publicado en 2017

Selective vulnerability of cerebellar granule neuroblasts and their progeny to drugs with abuse liability

artículo científico publicado en 2003

Short interfering RNA-induced gene silencing is transmitted between cells from the mammalian central nervous system

artículo científico publicado en 2006

Silencing the PTEN gene is protective against neuronal death induced by human immunodeficiency virus type 1 Tat.

artículo científico publicado en 2007

Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 Tat transgenic mice.

artículo científico publicado en 2012

Target-Derived Matricryptins Organize Cerebellar Synapse Formation through α3β1 Integrins

artículo científico publicado el 9 de agosto de 2012

Toll-like receptor expression and activation in astroglia: differential regulation by HIV-1 Tat, gp120, and morphine.

artículo científico publicado en 2011

Ultrastructural studies on Purkinje cell maturation in the cerebellum of the frog tadpole during spontaneous and thyroxine-induced metamorphosis

artículo científico publicado en 1982

beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration.

artículo científico publicado en 2010

kappa-opioid receptor expression defines a phenotypically distinct subpopulation of astroglia: relationship to Ca2+ mobilization, development, and the antiproliferative effect of opioids

artículo científico publicado en 1996

mu-Opioid receptor-induced Ca2+ mobilization and astroglial development: morphine inhibits DNA synthesis and stimulates cellular hypertrophy through a Ca(2+)-dependent mechanism

artículo científico publicado en 1996