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A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease

scientific article published on 04 November 2019

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart.

artículo científico publicado en 2013

Activation-induced cell death in T lymphocytes from multiple sclerosis patients

artículo científico publicado en 2014

Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death.

artículo científico publicado en 2015

BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways

artículo científico publicado en 2016

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

scientific article published on 01 January 2020

FAIM-L is an IAP-binding protein that inhibits XIAP ubiquitinylation and protects from Fas-induced apoptosis.

artículo científico publicado en 2013

FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration

artículo científico publicado en 2016

FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification

artículo científico publicado en 2015

Identification and characterization of new isoforms of human fas apoptotic inhibitory molecule (FAIM).

artículo científico publicado en 2017

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells

scientific journal article

MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness

artículo científico publicado en 2014

SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L

artículo científico publicado en 2020

TNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas.

artículo científico publicado en 2015

The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins

artículo científico publicado en 2010

The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis

artículo científico publicado en 2022

X-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.

artículo científico publicado en 2013