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A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood-brain barrier models for drug transport studies

scientific article published on 26 August 2020

A face-to-face comparison of the intra-amygdala and intrahippocampal kainate mouse models of mesial temporal lobe epilepsy and their utility for testing novel therapies

scientific article published on 11 December 2019

Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures

article published in the Proceedings of the National Academy of Sciences of the United States of America

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

artículo científico publicado en 2017

Consequences of housing conditions and interindividual diversity in rodent models of acquired epilepsy

scientific article published on 04 October 2019

Hydrolytic biotransformation of the bumetanide ester prodrug DIMAEB to bumetanide by esterases in neonatal human and rat serum and neonatal rat brain-A new treatment strategy for neonatal seizures?

artículo científico publicado en 2020

Mechanism of drug extrusion by brain endothelial cells via lysosomal drug trapping and disposal by neutrophils

article published in the Proceedings of the National Academy of Sciences of the United States of America

Novel Intrinsic Mechanisms of Active Drug Extrusion at the Blood-Brain Barrier: Potential Targets for Enhancing Drug Delivery to the Brain?

artículo científico publicado en 2020

P11 promoter methylation predicts the antidepressant effect of electroconvulsive therapy.

artículo científico publicado en 2018

Phenobarbital and midazolam suppress neonatal seizures in a noninvasive rat model of birth asphyxia, whereas bumetanide is ineffective

artículo científico publicado en 2020

Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?

artículo científico publicado en 2020

Structural, Molecular, and Functional Alterations of the Blood-Brain Barrier during Epileptogenesis and Epilepsy: A Cause, Consequence, or Both?

scientific article published on 16 January 2020

The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy

artículo científico publicado en 2020