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Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation

artículo científico publicado en 2019

BALB/c-Fcgr2b−/−Pdcd1−/− mouse expressing anti-urothelial antibody is a novel model of autoimmune cystitis ⬇️

artículo científico publicado el 19 de marzo de 2012

Dysregulated Generation of Follicular Helper T Cells in the Spleen Triggers Fatal Autoimmune Hepatitis in Mice ⬇️

artículo científico publicado el 13 de enero de 2011

Glucocorticoids potentiate the inhibitory capacity of programmed cell death 1 by up-regulating its expression on T cells

scientific article published on 13 November 2019

IFN-α Directly Promotes Programmed Cell Death-1 Transcription and Limits the Duration of T Cell-Mediated Immunity ⬇️

artículo científico publicado el 24 de enero de 2011

IFN-γ is reciprocally involved in the concurrent development of organ-specific autoimmunity in the liver and stomach

scientific article published on 13 October 2011

Intestinal CX 3 C chemokine receptor 1 high (CX 3 CR1 high ) myeloid cells prevent T-cell-dependent colitis ⬇️

artículo científico publicado el 7 de marzo de 2012

LAG-3 inhibits the activation of CD4 T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII

artículo científico publicado en 2018

LAG-3: from molecular functions to clinical applications

scientific article published on 01 September 2020

PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation

artículo científico publicado en 2019

PD-1 aborts the activation trajectory of autoreactive CD8+ T cells to prohibit their acquisition of effector functions

scientific article published on 02 July 2019

PD-1 efficiently inhibits T cell activation even in the presence of co-stimulation through CD27 and GITR

scientific article published on 14 February 2019

Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs

artículo científico publicado en 2016

Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses

scientific article published on 18 April 2019

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