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A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations.

artículo científico publicado en 2014

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

artículo científico publicado en 2019

Analysis of BRCA2 loss of heterozygosity in tumor tissue using droplet digital polymerase chain reaction.

artículo científico publicado en 2014

Combined blockade of activating mutations and ER results in synthetic lethality of ER+/HER2 mutant breast cancer

artículo científico publicado en 2018

Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA.

artículo científico publicado en 2015

Detection of cancer DNA in plasma of patients with early-stage breast cancer.

artículo científico publicado en 2014

ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients

artículo científico publicado en 2015

Extended adjuvant therapy with neratinib plus fulvestrant blocks ER/HER2 crosstalk and maintains complete responses of ER+/HER2+ breast cancers: Implications to the ExteNET trial

article

Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

artículo científico publicado en 2015

HER2 missense mutations have distinct effects on oncogenic signaling and migration.

artículo científico publicado en 2015

Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer.

artículo científico publicado en 2016

Ki-67 is required for maintenance of cancer stem cells but not cell proliferation.

artículo científico publicado en 2016

MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.

artículo científico publicado en 2014

NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability

artículo científico publicado en 2015

PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors

artículo científico publicado en 2017

PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.

artículo científico publicado en 2017

Pathogenic Germline Variants in Patients With Metastatic Breast Cancer

artículo científico publicado en 2019

TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer

artículo científico publicado en 2015

The estrogen receptor-alpha S118P variant does not affect breast cancer incidence or response to endocrine therapies

scientific article published in 2018

Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component

artículo científico publicado en 2017