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A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits

artículo científico publicado en 2015

A Genome-wide Association Study of Circulating Levels of Atorvastatin and Its Major Metabolites

artículo científico publicado en 2020

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

artículo científico publicado en 2018

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood.

artículo científico publicado en 2018

A TNF region haplotype offers protection from typhoid fever in Vietnamese patients

artículo científico publicado en 2007

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A comparison of case-only designs for detecting gene x gene interaction in rheumatoid arthritis using genome-wide case-control data in Genetic Analysis Workshop 16

artículo científico publicado en 2009

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A flexible approach for the analysis of rare variants allowing for a mixture of effects on binary or quantitative traits

artículo científico publicado en 2013

A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility

artículo científico publicado en 2008

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia.

artículo científico publicado en 2018

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A powerful approach to sub-phenotype analysis in population-based genetic association studies

artículo científico publicado en 2010

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A rare-variant test for high-dimensional data

artículo científico publicado en 2017

A second generation human haplotype map of over 3.1 million SNPs

artículo científico publicado en 2007

A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits

artículo científico publicado en 2016

ARIEL and AMELIA: testing for an accumulation of rare variants using next-generation sequencing data

artículo científico publicado en 2012

Abstract 4683: Smoking is associated with mosaic loss of chromosome Y

Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.

artículo científico publicado en 2017

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets

artículo científico publicado en 2005

An evaluation of statistical approaches to rare variant analysis in genetic association studies

artículo científico publicado en 2010

An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

artículo científico publicado en 2014

Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis

scientific article published on 02 September 2020

Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry

artículo científico publicado en 2017

Assessing the impact of missing genotype data in rare variant association analysis

artículo científico publicado en 2011

Assessment of sex-specific effects in a genome-wide association study of rheumatoid arthritis

artículo científico publicado en 2009

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

artículo científico publicado en 2015

Association between endometriosis and the interleukin 1A (IL1A) locus

artículo científico publicado en 2014

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany

artículo científico publicado en 2010

Association of the KIAA0319 dyslexia susceptibility gene with reading skills in the general population.

artículo científico publicado en 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

artículo científico publicado en 2007

Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis

artículo científico publicado en 2014

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

article

Basic statistical analysis in genetic case-control studies

artículo científico publicado en 2011

Beyond Endometriosis Genome-Wide Association Study: From Genomics to Phenomics to the Patient

artículo científico publicado en 2016

CCRaVAT and QuTie-enabling analysis of rare variants in large-scale case control and quantitative trait association studies

artículo científico publicado en 2010

Clinical and genetic correlates of growth differentiation factor 15 in the community

artículo científico publicado en 2012

Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms

artículo científico publicado en 2020

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

scientific article published on 01 February 2019

Common variants in left/right asymmetry genes and pathways are associated with relative hand skill

artículo científico publicado en 2013

Comparison of methods for transcriptome imputation through application to two common complex diseases

artículo científico publicado en 2018

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

artículo científico publicado en 2012

Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children.

artículo científico publicado en 2017

Correction: Comparison of methods for transcriptome imputation through application to two common complex diseases

artículo científico publicado en 2020

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Correction: The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits.

artículo científico publicado en 2013

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

artículo científico publicado en 2016

DCDC2, KIAA0319 and CMIP are associated with reading-related traits

artículo científico publicado en 2011

Data quality control in genetic case-control association studies.

artículo científico publicado en 2010

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

artículo científico publicado en 2021

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk

artículo científico publicado en 2009

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

artículo científico publicado en 2015

Discovery and fine mapping of serum protein loci through transethnic meta-analysis

artículo científico publicado en 2012

Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations

artículo científico publicado en 2017

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Disentangling the genetics of lean mass

article

Efficiency and consistency of haplotype tagging of dense SNP maps in multiple samples.

artículo científico publicado en 2004

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Erratum: Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2

scholarly article published in Nature Genetics

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

artículo científico publicado en 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci

artículo científico publicado en 2015

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

artículo científico publicado en 2017

Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms

artículo científico publicado en 2008

Evaluation of methodology for the analysis of 'time-to-event' data in pharmacogenomic genome-wide association studies

artículo científico publicado en 2016

Examining the statistical properties of fine-scale mapping in large-scale association studies

artículo científico publicado en 2008

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

artículo científico publicado en 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Exploiting horizontal pleiotropy to search for causal pathways within a Mendelian randomization framework

scientific article published on 21 February 2020

Fine mapping versus replication in whole-genome association studies

artículo científico publicado en 2007

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

artículo científico publicado en 2018

Fine-scale population structure in the UK Biobank: implications for genome-wide association studies

artículo científico publicado en 2020

Functional analysis of epilepsy-associated variants in STXBP1/Munc18-1 using humanized Caenorhabditis elegans

artículo científico publicado en 2020

Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability

artículo científico publicado en 2021

Functional validity, role, and implications of heavy alcohol consumption genetic loci

artículo científico publicado en 2020

GWAMA: software for genome-wide association meta-analysis

artículo científico publicado en 2010

GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb

artículo científico publicado en 2015

Gearing up for genome-wide gene-association studies.

artículo científico publicado en 2005

Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

artículo científico publicado en 2014

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

artículo científico publicado en 2016

Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus

artículo científico publicado en 2020

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

scientific article published on 11 September 2020

Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus

artículo científico publicado en 2021

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome

artículo científico publicado en 2020

Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p'-dde levels in a population-based sample

artículo científico publicado en 2016

Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations

artículo científico publicado en 2013

Genetic associations with clozapine-induced myocarditis in patients with schizophrenia

artículo científico publicado en 2020

Genetic burden associated with varying degrees of disease severity in endometriosis

artículo científico publicado en 2015

Genetic evidence of assortative mating in humans

article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

artículo científico publicado en 2018

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

artículo científico publicado en 2022

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.

artículo científico publicado en 2018

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets

artículo científico publicado en 2014

Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample

artículo científico publicado en 2014

Genetic variation in the CYP2B6 gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study

artículo científico publicado en 2014

Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants

artículo científico publicado en 2005

Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study

artículo científico publicado en 2019

Genetics of kidney traits in worldwide populations: the Continental Origins and Genetic Epidemiology Network (COGENT) Kidney Consortium

artículo científico publicado en 2020

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome Wide Association Scan identifies new variants associated with a cognitive predictor of dyslexia

Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity

article

Genome-Wide Association Study Identifies a Locus at 7p15.2 Associated With Endometriosis

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis

scientific article published on 01 March 2020

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

artículo científico publicado en 2016

Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15

artículo científico

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

artículo científico publicado en 2016

Genome-wide and fine-resolution association analysis of malaria in West Africa

artículo científico publicado en 2009

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

artículo científico publicado en 2017

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

artículo científico publicado en 2010

Genome-wide association analysis and replication of coronary artery disease in South Korea suggests a causal variant common to diverse populations

artículo científico publicado en 2010

Genome-wide association analysis identifies 27 novel loci associated with uterine leiomyomata revealing common genetic origins with endometriosis

Genome-wide association analysis identifies six new loci associated with forced vital capacity

artículo científico publicado en 2014

Genome-wide association analysis of imputed rare variants: application to seven common complex diseases

artículo científico publicado en 2012

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

artículo científico publicado en 2019

Genome-wide association meta-analysis identifies new endometriosis risk loci

artículo científico publicado en 2012

Genome-wide association scan allowing for epistasis in type 2 diabetes

artículo científico publicado en 2010

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia

artículo científico publicado en 2019

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis

artículo científico publicado en 2011

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India

artículo científico publicado en 2013

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

artículo científico publicado en 2011

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

artículo científico publicado en 2010

Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population

artículo científico publicado en 2017

Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample

artículo científico publicado en 2015

Genome-wide association study of type 2 diabetes in Africa.

artículo científico publicado en 2019

Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia

artículo científico publicado en 2020

Genome-wide associations for birth weight and correlations with adult disease

artículo científico publicado en 2016

Genome-wide detection and characterization of positive selection in human populations

artículo científico publicado en 2007

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci

artículo científico publicado en 2014

Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis

artículo científico publicado en 2017

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

artículo científico publicado en 2020

Genotype prediction using a dense map of SNPs

artículo científico publicado en 2004

Goldsurfer2 (Gs2): a comprehensive tool for the analysis and visualization of genome wide association studies

artículo científico publicado en 2008

Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes

artículo científico publicado en 2016

How useful is the fine-scale mapping of complex trait linkage peaks? Evaluating the impact of additional microsatellite genotyping on the posterior probability of linkage.

artículo científico publicado en 2005

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney

artículo científico publicado en 2020

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

artículo científico publicado en 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

artículo científico publicado en 2016

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

artículo científico publicado en 2017

Identification of novel putative rheumatoid arthritis susceptibility genes via analysis of rare variants

artículo científico publicado en 2009

Identification of type 2 diabetes loci in 433,540 East Asian individuals

artículo científico publicado en 2020

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues

artículo científico publicado en 2016

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

artículo científico publicado en 2013

Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel

artículo científico publicado en 2017

Insights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets.

artículo científico publicado en 2012

Integrative cross tissue analysis of gene expression identifies novel type 2 diabetes genes

article

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

artículo científico publicado en 2016

Investigating the clinical factors and comedications associated with circulating levels of atorvastatin and its major metabolites in secondary prevention

scientific article published on 04 January 2020

Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits

artículo científico publicado en 2022

Investigating the prevalence, predictors, and prognosis of suboptimal statin use early after a non-ST elevation acute coronary syndrome

artículo científico publicado en 2016

Investigation of prediction accuracy and the impact of sample size, ancestry, and tissue in transcriptome-wide association studies

scientific article published on 19 March 2020

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

artículo científico publicado en 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

artículo científico publicado en 2017

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditions

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

artículo científico publicado en 2014

Linkage disequilibrium mapping via cladistic analysis of phase-unknown genotypes and inferred haplotypes in the Genetic Analysis Workshop 14 simulated data

artículo científico publicado en 2005

Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes

artículo científico publicado en 2004

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

artículo científico publicado en 2014

Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk

artículo científico publicado en 2011

MARV: a tool for genome-wide multi-phenotype analysis of rare variants

artículo científico publicado en 2017

Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31

artículo científico publicado en 2020

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

artículo científico publicado en 2017

Marker selection for genetic case-control association studies

artículo científico publicado en 2009

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

artículo científico publicado en 2019

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

artículo científico publicado en 2017

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

article by Sara Pulit et al published 1 January 2019 in Human Molecular Genetics

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

artículo científico publicado en 2011

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

artículo científico publicado en 2013

Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs

artículo científico publicado en 2016

Meta-analysis of sex-specific genome-wide association studies

artículo científico publicado en 2010

Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits

artículo científico publicado en 2014

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer

artículo científico publicado en 2014

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ethnic genome-wide association study for atrial fibrillation

article

Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility

artículo científico publicado en 2016

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2018

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation

artículo científico publicado en 2016

Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity

artículo científico publicado en 2003

Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

artículo científico publicado en 2022

Mutagenesis. Smoking is associated with mosaic loss of chromosome Y.

artículo científico publicado en 2014

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

artículo científico publicado en 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

artículo científico publicado en 2015

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group

artículo científico publicado en 2010

PCSK6 is associated with handedness in individuals with dyslexia

artículo científico publicado en 2011

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Pharmacogenetics of TNF inhibitor response in rheumatoid arthritis utilizing the two-component disease activity score

scientific article published on 30 October 2020

Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

artículo científico publicado en 2019

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

artículo científico publicado en 2017

Rapid testing of gene-gene interactions in genome-wide association studies of binary and quantitative phenotypes

artículo científico publicado en 2011

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis

artículo científico publicado en 2010

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

artículo científico publicado en 2018

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

artículo científico publicado en 2018

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

artículo científico publicado en 2007

SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes

artículo científico publicado en 2017

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions

artículo científico publicado en 2019

Shared genetics underlying epidemiological association between endometriosis and ovarian cancer

artículo científico publicado en 2015

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

artículo científico publicado en 2015

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

artículo científico publicado en 2012

SurvivalGWAS_Power: a user friendly tool for power calculations in pharmacogenetic studies with "time to event" outcomes

artículo científico publicado en 2016

SurvivalGWAS_SV: software for the analysis of genome-wide association studies of imputed genotypes with "time-to-event" outcomes

artículo científico publicado en 2017

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The dyslexia candidate locus on 2p12 is associated with general cognitive ability and white matter structure

artículo científico publicado en 2012

The genetic architecture of sporadic and multiple consecutive miscarriage

scientific article published on 25 November 2020

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The impact of SNP density on fine-scale patterns of linkage disequilibrium

artículo científico publicado en 2004

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits

artículo científico publicado en 2012

The power of genetic diversity in genome-wide association studies of lipids

The trans-ancestral genomic architecture of glycemic traits

The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits

artículo científico publicado en 2011

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity

artículo científico publicado en 2016

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

artículo científico publicado en 2016

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

artículo científico publicado en 2019

Trans-ethnic meta-analysis of white blood cell phenotypes

artículo científico publicado en 2014

Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution

artículo científico publicado en 2017

Trans-ethnic study design approaches for fine-mapping

artículo científico publicado en 2016

Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms

artículo científico publicado en 2016

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Two-stage two-locus models in genome-wide association

artículo científico publicado en 2006

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa

scientific article published on 01 October 2019

VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5

artículo científico publicado en 2008

Variability of genome-wide DNA methylation and mRNA expression profiles in reproductive and endocrine disease related tissues

artículo científico publicado en 2017

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease

artículo científico publicado en 2021

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

artículo científico publicado en 2017

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