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Lista de obras de Jonathan Hirst

15-Hydroxyprostaglandin dehydrogenase expression and localization in guinea pig gestational tissues during late pregnancy and parturition.

artículo científico publicado en 2012

A tale of two steroids: The importance of the androgens DHEA and DHEAS for early neurodevelopment

artículo científico publicado en 2018

Administration of Progesterone Throughout Pregnancy Increases Maternal Steroids Without Adverse Effect on Mature Oligodendrocyte Immunostaining in the Guinea Pig.

artículo científico publicado en 2017

Allopregnanolone in the brain and blood after disruption of the hypothalamic-pituitary-adrenal axis in fetal sheep

artículo científico publicado en 2004

Allopregnanolone in the brain: protecting pregnancy and birth outcomes.

artículo científico publicado en 2013

Antenatal prevention of cerebral palsy and childhood disability: is the impossible possible?

scientific article published on 21 July 2018

Birth and Neonatal Transition in the Guinea Pig: Experimental Approaches to Prevent Preterm Birth and Protect the Premature Fetus

artículo científico publicado en 2018

Blocked, delayed, or obstructed: What causes poor white matter development in intrauterine growth restricted infants?

artículo científico publicado en 2017

Brain allopregnanolone in the fetal and postnatal rat in response to uteroplacental insufficiency.

artículo científico publicado en 2008

Cerebellar Changes in Guinea Pig Offspring Following Suppression of Neurosteroid Synthesis During Late Gestation

artículo científico publicado en 2016

Cerebrovascular responses in the fetal sheep brain to low-dose endotoxin

artículo científico publicado en 2004

Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in fetal sheep with umbilicoplacental embolization

artículo científico publicado en 2003

Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in the perinatal sheep

artículo científico publicado en 2003

Changes in Neuroactive Steroid Concentrations After Preterm Delivery in the Guinea Pig

artículo científico publicado el 12 de abril de 2013

Changes in human placental 5alpha-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposure

artículo científico publicado en 2009

Delay of preterm birth in sheep by THG113.31, a prostaglandin F2alpha receptor antagonist

artículo científico publicado en 2005

Disruptions to the cerebellar GABAergic system in juvenile guinea pigs following preterm birth

artículo científico publicado en 2017

Effect of postnatal progesterone therapy following preterm birth on neurosteroid concentrations and cerebellar myelination in guinea pigs.

artículo científico publicado en 2015

Effects of combined IUGR and prenatal stress on the development of the hippocampus in a fetal guinea pig model.

artículo científico publicado en 2017

Effects of prenatal stress on behavioural and neurodevelopmental outcomes are altered by maternal separation in the neonatal period

artículo científico publicado en 2020

Effects of prenatal stress on fetal neurodevelopment and responses to maternal neurosteroid treatment in Guinea pigs

artículo científico publicado en 2013

Endotoxin increases sleep and brain allopregnanolone concentrations in newborn lambs

artículo científico publicado en 2002

Fetal responses to maternal and intra-amniotic lipopolysaccharide administration in sheep

artículo científico publicado en 2002

Ganaxolone versus Phenobarbital for Neonatal Seizure Management

artículo científico publicado en 2022

Ganaxolone: A New Treatment for Neonatal Seizures.

artículo científico publicado en 2017

Genes upregulated in the amnion at labour are bivalently marked by activating and repressive histone modifications

scientific article published on 01 April 2019

Hypoxia potentiates endotoxin-induced allopregnanolone concentrations in the newborn brain

artículo científico publicado en 2006

Identification of bactenecin-1 in cervicovaginal fluid by two-dimensional electrophoresis in an ovine model of preterm labour

artículo científico publicado en 2007

Identification of kynurenine pathway enzyme mRNAs and metabolites in human placenta: up-regulation by inflammatory stimuli and with clinical infection

artículo científico publicado en 2005

Increased allopregnanolone levels in the fetal sheep brain following umbilical cord occlusion

artículo científico publicado en 2004

Increased anxiety-like phenotype in female guinea pigs following reduced neurosteroid exposure in utero

artículo científico publicado en 2017

Increased expression of alpha-enolase in cervico-vaginal fluid during labour

artículo científico publicado en 2010

Increased placental neurosteroidogenic gene expression precedes poor outcome in the preterm guinea pig.

artículo científico publicado en 2014

Inflammatory and steroid receptor gene methylation in the human amnion and decidua

artículo científico publicado en 2013

Inhibition of prostaglandin synthesis and its effect on uterine activity during established premature labor in sheep

artículo científico publicado el 1 de septiembre de 2001

Injury of the developing cerebellum: a brief review of the effects of endotoxin and asphyxial challenges in the late gestation sheep fetus.

artículo científico

Invited review: guinea pig models for translation of DOHaD into the clinic.

artículo científico publicado en 2018

Labor-associated regulation of prostaglandin E and F synthesis and action in the ovine amnion and cervix

artículo científico publicado en 2005

Late stage functionalization via Chan-Lam amination: rapid access to potent and selective integrin inhibitors

scientific article published on 04 March 2020

Long-term effects of preterm birth on behavior and neurosteroid sensitivity in the guinea pig.

artículo científico publicado en 2016

Loss of neurosteroid-mediated protection following stress during fetal life.

artículo científico

Maternal stress in pregnancy affects myelination and neurosteroid regulatory pathways in the guinea pig cerebellum

artículo científico publicado en 2017

Mechanisms leading to increased risk of preterm birth in growth-restricted guinea pig pregnancies

artículo científico publicado en 2013

Molecular evidence of a (pro)renin/ (pro)renin receptor system in human intrauterine tissues in pregnancy and its association with PGHS-2

scientific article published on 11 August 2010

Neuroactive steroids in pregnancy: key regulatory and protective roles in the foetal brain.

artículo científico publicado en 2013

Neuroactive steroids induce changes in fetal sheep behavior during normoxic and asphyxic states.

artículo científico publicado en 2010

Neurosteroid replacement therapy using the allopregnanolone-analogue ganaxolone following preterm birth in male guinea pigs

scientific article published on 20 September 2018

Neurosteroids for a successful pregnancy

artículo científico publicado en 2011

Neurosteroids in the fetus and neonate: potential protective role in compromised pregnancies

artículo científico publicado en 2007

PTGS2 (prostaglandin endoperoxide synthase-2) expression in term human amnion in vivo involves rapid mRNA turnover, polymerase-II 5'-pausing, and glucocorticoid transrepression

artículo científico publicado en 2011

Perinatal compromise contributes to programming of GABAergic and glutamatergic systems leading to long-term effects on offspring behaviour

scientific article published on 09 December 2019

Prenatal Stress Alters Hippocampal Neuroglia and Increases Anxiety in Childhood.

artículo científico publicado en 2015

Preterm birth affects GABAA receptor subunit mRNA levels during the foetal-to-neonatal transition in guinea pigs.

artículo científico publicado en 2015

Progesterone Receptor Isoform Expression in Response to in utero Growth Restriction in the Fetal Guinea Pig Brain

artículo científico publicado el 11 de abril de 2012

Progesterone receptor expression declines in the guinea pig uterus during functional progesterone withdrawal and in response to prostaglandins

artículo científico publicado en 2014

Progesterone receptor isoform expression in the guinea pig myometrium from normal and growth restricted pregnancies

artículo científico publicado en 2010

Prostaglandin D synthase in the prenatal ovine brain and effects of its inhibition with selenium chloride on fetal sleep/wake activity in utero.

artículo científico publicado en 2002

Prostaglandin e and f receptor expression and myometrial sensitivity at labor onset in the sheep

artículo científico publicado en 2004

Reduced Neurosteroid Exposure Following Preterm Birth and Its' Contribution to Neurological Impairment: A Novel Avenue for Preventative Therapies

scientific article published on 15 May 2019

Severity and timing: How prenatal stress exposure affects glial developmental, emotional behavioural and plasma neurosteroid responses in guinea pig offspring

artículo científico publicado en 2016

Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development

artículo científico publicado en 2010

Steroid hormone receptors in the adrenal glands of fetal and adult rhesus monkeys

artículo científico publicado el 1 de julio de 1992

Steroid-sensitive GABAA receptors in the fetal sheep brain.

artículo científico publicado en 2003

Stress in pregnancy activates neurosteroid production in the fetal brain

artículo científico publicado en 2006

Stress in pregnancy: a role for neuroactive steroids in protecting the fetal and neonatal brain

artículo científico publicado en 2009

The guinea pig as an animal model for studying perinatal changes in microvascular function

artículo científico publicado en 2012

The relationship between immunosuppressive activity and immunoregulatory cytokines in seminal plasma: influence of sperm autoimmunity and seminal leukocytes

artículo científico publicado en 2006