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A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors

artículo científico publicado en 2020

A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

artículo científico publicado en 2015

Activation of nuclear factor-kappa B by linear ubiquitin chain assembly complex contributes to lung metastasis of osteosarcoma cells

artículo científico publicado en 2011

An autosomal recessive mutation of DSG4 causes monilethrix through the ER stress response

artículo científico publicado en 2015

Decreased linear ubiquitination of NEMO and FADD on apoptosis with caspase-mediated cleavage of HOIP.

artículo científico publicado en 2017

Direct Virus Inactivation of Tachyplesin I and Its Isopeptides from Horseshoe Crab Hemocytes

artículo científico publicado el 1 de enero de 1991

Endoplasmic reticulum stress in the pathogenesis of pretibial dystrophic epidermolysis bullosa

scientific article published on 27 August 2017

Generalized verrucosis caused by various human papillomaviruses in a patient with GATA2 deficiency.

artículo científico publicado en 2017

Generation of Rat Monoclonal Antibodies Against a Deubiquitinase, Ovarian Tumor Domain-Containing Protein 1

scientific article published on 21 August 2018

Generation of Rat Monoclonal Antibodies Specific for DZIP3

artículo científico publicado en 2018

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

artículo científico publicado en 2017

High-Throughput Screening for Linear Ubiquitin Chain Assembly Complex (LUBAC) Selective Inhibitors Using Homogenous Time-Resolved Fluorescence (HTRF)-Based Assay System

artículo científico publicado en 2018

Identification of linear polyubiquitin chain immunoreactivity in tau pathology of Alzheimer's disease

artículo científico publicado en 2019

Identification of one base deletion in exon IX of the protein C gene that causes a type I deficiency

artículo científico publicado el 1 de diciembre de 1992

In-frame Val216-Ser217 deletion of KIT in mild piebaldism causes aberrant secretion and SCF response.

artículo científico publicado en 2018

Intracellular degradation of secretion defect‐type mutants of antithrombin is inhibited by proteasomal inhibitors

artículo científico publicado el 21 de julio de 1997

Isolation and characterization of a thermolabile β-2 macroglycoprotein (‘thermolabile substance’ or ‘Hakata antigen’) detected by precipitating (auto) antibody in sera of patients with systemic lupus erythematosus

artículo científico publicado el 12 de julio de 1991

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.

artículo científico publicado en 2015

Linear Polyubiquitin Chain Modification of TDP-43-Positive Neuronal Cytoplasmic Inclusions in Amyotrophic Lateral Sclerosis

scientific article published on 01 March 2020

Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction

artículo científico publicado el 4 de febrero de 2011

Linear Ubiquitin Code: Its Writer, Erasers, Decoders, Inhibitors, and Implications in Disorders

scientific article published on 11 May 2020

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

artículo científico publicado en 2016

Linear ubiquitination: A novel NF-κB regulatory mechanism for inflammatory and immune responses by the LUBAC ubiquitin ligase complex [Review]

artículo científico publicado el 19 de mayo de 2012

Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses

scientific article published on 03 April 2020

Molecular cloning of two types of cDNA encoding subunit RC6-I of rat proteasomes

artículo científico publicado el 17 de octubre de 1995

Preparation and properties of monoclonal antibodies against lipopolysaccharide-sensitive serine protease zymogen, factor C, from horseshoe crab (Tachypleus tridentatus) hemocytes

artículo científico publicado el 1 de octubre de 1992

Purified horseshoe crab factor G. Reconstitution and characterization of the (1-->3)-beta-D-glucan-sensitive serine protease cascade

scientific article published in 1995

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

artículo científico publicado en 2013

Reduced SHARPIN and LUBAC Formation May Contribute to CCl₄- or Acetaminophen-Induced Liver Cirrhosis in Mice

artículo científico publicado en 2017

Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling

scientific article published on 02 January 2019

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation

artículo científico publicado en 2012

Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide.

artículo científico publicado en 2016

Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1

artículo científico publicado en 2018

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity.

artículo científico publicado en 2015

Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling

artículo científico publicado en 2019

The E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD

scientific article published on 31 July 2019

The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3.

artículo científico publicado en 2015

cDNA cloning of rat proteasome subunit RC1, a homologue of RING10 located in the human MHC class II region

artículo científico publicado el 13 de abril de 1992