Lista de obras -

5'-Triphosphate RNA is the ligand for RIG-I

artículo científico publicado en 2006

A human in vitro whole blood assay to predict the systemic cytokine response to therapeutic oligonucleotides including siRNA

artículo científico publicado en 2013

Abstract B44: Selective stimulation of RIG-I with a novel synthetic RNA induces strong anti-tumor immunity in mouse tumor models

Accessing the therapeutic potential of immunostimulatory nucleic acids

scientific article published on 30 July 2008

Active NF-kappaB signalling is a prerequisite for influenza virus infection.

artículo científico publicado en 2004

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

artículo científico publicado en 2014

Approaching the RNA ligand for RIG-I?

artículo científico publicado en 2009

C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma

artículo científico publicado en 2007

Delivery with polycations extends the immunostimulant Ribomunyl® into a potent antiviral Toll-like receptor 7/8 agonist

article published in 2011

Discriminating self from non-self in nucleic acid sensing

artículo científico publicado en 2016

Enzymatic synthesis and purification of a defined RIG-I ligand

artículo científico publicado en 2014

Exosomes as nucleic acid nanocarriers

artículo científico

Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes

artículo científico publicado en 2004

G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes

artículo científico publicado en 2016

Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA.

artículo científico publicado en 2009

Human TLR8 Senses RNA From -Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells

Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary B cells by EBV.

artículo científico publicado en 2004

Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells

artículo científico publicado en 2005

MDM2 is recognized as a tumor-associated antigen in chronic lymphocytic leukemia by CD8+ autologous T lymphocytes

artículo científico publicado en 2006

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation

artículo científico publicado en 2005

Master sensors of pathogenic RNA - RIG-I like receptors

artículo científico

Monocyte-Mediated Inhibition of TLR9-Dependent IFN- Induction in Plasmacytoid Dendritic Cells Questions Bacterial DNA as the Active Ingredient of Bacterial Lysates

artículo científico publicado en 2010

RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection

artículo científico publicado en 2017

RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation

artículo científico publicado en 2017

RIG-I activation induces the release of extracellular vesicles with antitumor activity

artículo científico publicado en 2016

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

artículo científico publicado en 2012

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells

artículo científico publicado en 2013

RNA recognition via TLR7 and TLR8.

artículo científico publicado en 2008

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

artículo científico publicado en 2009

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

artículo científico publicado en 2009

Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.

artículo científico publicado en 2009

Selective and direct activation of human neutrophils but not eosinophils by Toll-like receptor 8.

artículo científico publicado en 2009

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

artículo científico publicado en 2005

SiRNA delivery with exosome nanoparticles.

artículo científico publicado en 2011

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system

artículo científico publicado en 2005

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

artículo científico publicado en 2010

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma

artículo científico publicado en 2013

The chase for the RIG-I ligand--recent advances

artículo científico publicado en 2010

c-MYC impairs immunogenicity of human B cells

artículo científico publicado en 2007

c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells

scientific article published on 04 March 2009

siRNA and isRNA: two edges of one sword

artículo científico publicado en 2006

Lista de obras de

5'-Triphosphate RNA is the ligand for RIG-I

A human in vitro whole blood assay to predict the systemic cytokine response to therapeutic oligonucleotides including siRNA

Abstract B44: Selective stimulation of RIG-I with a novel synthetic RNA induces strong anti-tumor immunity in mouse tumor models

Accessing the therapeutic potential of immunostimulatory nucleic acids

Active NF-kappaB signalling is a prerequisite for influenza virus infection.

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

Approaching the RNA ligand for RIG-I?

C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma

Delivery with polycations extends the immunostimulant Ribomunyl® into a potent antiviral Toll-like receptor 7/8 agonist

Discriminating self from non-self in nucleic acid sensing

Enzymatic synthesis and purification of a defined RIG-I ligand

Exosomes as nucleic acid nanocarriers

Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes

G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes

Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA.

Human TLR8 Senses RNA From -Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells

Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary B cells by EBV.

Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells

MDM2 is recognized as a tumor-associated antigen in chronic lymphocytic leukemia by CD8+ autologous T lymphocytes

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation

Master sensors of pathogenic RNA - RIG-I like receptors

Monocyte-Mediated Inhibition of TLR9-Dependent IFN- Induction in Plasmacytoid Dendritic Cells Questions Bacterial DNA as the Active Ingredient of Bacterial Lysates

RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection

RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation

RIG-I activation induces the release of extracellular vesicles with antitumor activity

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells

RNA recognition via TLR7 and TLR8.

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.

Selective and direct activation of human neutrophils but not eosinophils by Toll-like receptor 8.

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

SiRNA delivery with exosome nanoparticles.

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma

The chase for the RIG-I ligand--recent advances

c-MYC impairs immunogenicity of human B cells

c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells

siRNA and isRNA: two edges of one sword