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A Multifunctional Monooxygenase XanO4 Catalyzes Xanthone Formation in Xantholipin Biosynthesis via a Cryptic Demethoxylation

artículo científico publicado en 2016

Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps.

artículo científico publicado en 2017

DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome

artículo científico publicado en 2020

DndEi Exhibits Helicase Activity Essential for DNA Phosphorothioate Modification and ATPase Activity Strongly Stimulated by DNA Substrate with a GAAC/GTTC Motif

artículo científico publicado en 2015

Epigenetic competition reveals density-dependent regulation and target site plasticity of phosphorothioate epigenetics in bacteria

artículo científico publicado en 2020

Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment.

artículo científico publicado en 2012

Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences

artículo científico publicado en 2014

In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex

artículo científico publicado en 2015

Nick-seq for single-nucleotide resolution genomic maps of DNA modifications and damage

artículo científico publicado en 2020

Oxidation of phosphorothioate DNA modifications leads to lethal genomic instability.

artículo científico publicado en 2017

Pathological phenotypes and in vivo DNA cleavage by unrestrained activity of a phosphorothioate-based restriction system in Salmonella

artículo científico publicado en 2014

Quantitative mapping of the cellular small RNA landscape with AQRNA-seq

artículo científico publicado en 2021

Regulation of DNA phosphorothioate modifications by the transcriptional regulator DptB in Salmonella.

artículo científico