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APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation

artículo científico publicado en 2016

Cleavage of the APE1 N-Terminal Domain in Acute Myeloid Leukemia Cells Is Associated with Proteasomal Activity

scientific article published on 31 March 2020

Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.

artículo científico publicado en 2013

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

artículo científico publicado en 2017

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

artículo científico publicado en 2012

Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins.

artículo científico publicado en 2014

Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin).

artículo científico publicado en 2013

SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements.

artículo científico publicado en 2013

SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing

scientific article published on 01 August 2019

Telomere maintenance: regulating hTERC fate through RNA modifications

artículo científico publicado en 2019

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