Lista de obras -

A Canadian consensus on the management of newly diagnosed and relapsed acute promyelocytic leukemia in adults

artículo científico publicado en 2014

A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection.

artículo científico publicado en 2017

A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia

artículo científico publicado en 2018

A predictive model of response to erythropoietin stimulating agents in myelodysplastic syndrome: from the Canadian MDS patient registry

artículo científico publicado en 2017

Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche

artículo científico publicado en 2017

Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax

scientific article published on 27 January 2020

An MDS-specific frailty index based on cumulative deficits adds independent prognostic information to clinical prognostic scoring

artículo científico publicado en 2019

Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2

artículo científico publicado en 2019

Cellular Reprogramming Allows Generation of Autologous Hematopoietic Progenitors From AML Patients That Are Devoid of Patient-Specific Genomic Aberrations ⬇️

artículo científico publicado en 2015

Cyclic thrombocytopenia with statistically significant neutrophil oscillations.

artículo científico publicado en 2018

Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib

artículo científico publicado en 2014

Evidence-based guidelines for the use of tyrosine kinase inhibitors in adults with Philadelphia chromosome-positive or BCR-ABL-positive acute lymphoblastic leukemia: a Canadian consensus

artículo científico

Evolving Therapeutic Options for Polycythemia Vera: Perspectives of the Canadian Myeloproliferative Neoplasms Group

artículo científico publicado en 2015

Examining the molecular mechanism of bcl-2 family proteins at membranes by fluorescence spectroscopy

artículo científico publicado en 2014

Fornix fibers and motivational states as controllers of behavior: a study stimulated by the contextual retrieval theory

artículo científico publicado el 1 de abril de 1978

Hand Mirror Cells and Hypercalcemia: A Rare Presentation of Pediatric Acute Lymphoblastic Leukemia

artículo científico publicado en 2020

High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells

artículo científico publicado en 2016

How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry

artículo científico publicado en 2018

ITACA: A new validated international erythropoietic stimulating agent-response score that further refines the predictive power of previous scoring systems

artículo científico publicado en 2017

Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence

artículo científico publicado en 2018

Increased eculizumab requirements during pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: case report and review of the literature.

artículo científico publicado en 2014

Iron overload in myelodysplastic syndromes: Evidence based guidelines from the Canadian consortium on MDS

article

Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells.

artículo científico publicado en 2016

Laboratory Investigation of Myeloproliferative Neoplasms (MPNs): Recommendations of the Canadian Mpn Group

artículo científico publicado en 2016

Long-term outcome of a pediatric-inspired regimen used for adults aged 18-50 years with newly diagnosed acute lymphoblastic leukemia.

artículo científico publicado en 2014

Mixed variant multicentric Castleman disease treated with rituximab: case report

artículo científico publicado en 2010

Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells--Mitochondrial Outer Membrane Permeabilization and Beyond

artículo científico

Molecular genetic basis for the antiidiotypic antibody response associated with successful renal allograft survival in humans

artículo científico publicado el 1 de febrero de 1991

Morphology of acute promyelocytic leukemia with cytogenetic or molecular evidence for the diagnosis: Characterization of additional microgranular variants ⬇️

artículo científico publicado el 1 de noviembre de 1997

Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid

artículo científico publicado en 2014

Optimizing outcomes with azacitidine: recommendations from Canadian centres of excellence.

artículo científico publicado en 2014

Overall survival in lower IPSS risk MDS by receipt of iron chelation therapy, adjusting for patient-related factors and measuring from time of first red blood cell transfusion dependence: an MDS-CAN analysis.

artículo científico publicado en 2017

Patient-related factors independently impact overall survival in patients with myelodysplastic syndromes: an MDS-CAN prospective study.

artículo científico

Phase II study of targeted therapy with temozolomide in acute myeloid leukaemia and high-risk myelodysplastic syndrome patients pre-screened for low O(6) -methylguanine DNA methyltransferase expression

artículo científico publicado en 2014

Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance.

artículo científico publicado en 2018

Randomized phase II comparison of standard CHOP with weekly CHOP in elderly patients with non-Hodgkin's lymphoma ⬇️

artículo científico publicado el 1 de septiembre de 1995

Regulating cell death at, on, and in membranes.

artículo científico publicado en 2014

Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatm

artículo científico publicado en 2019

Sam68 Allows Selective Targeting of Human Cancer Stem Cells

artículo científico publicado en 2017

Still embedded together binding to membranes regulates Bcl-2 protein interactions.

artículo científico publicado en 2010

Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results.

artículo científico publicado en 2017

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

scientific article published on 24 January 2020

The predictive value of intracellular imatinib levels in newly diagnosed chronic myeloid leukemia

scientific article published on 05 December 2019

The proapoptotic protein tBid forms both superficially bound and membrane-inserted oligomers.

artículo científico publicado en 2014

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation

artículo científico publicado en 2014

Treatment of older patients with acute myeloid leukemia (AML): revised Canadian consensus guidelines

artículo científico publicado en 2017

Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove

artículo científico publicado en 2018

cml biology for the clinician in 2011: six impossible things to believe before breakfast on the way to cure.

artículo científico publicado en 2011

Lista de obras de

A Canadian consensus on the management of newly diagnosed and relapsed acute promyelocytic leukemia in adults

A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection.

A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia

A predictive model of response to erythropoietin stimulating agents in myelodysplastic syndrome: from the Canadian MDS patient registry

Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche

Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax

An MDS-specific frailty index based on cumulative deficits adds independent prognostic information to clinical prognostic scoring

Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2

Cellular Reprogramming Allows Generation of Autologous Hematopoietic Progenitors From AML Patients That Are Devoid of Patient-Specific Genomic Aberrations ⬇️

Cyclic thrombocytopenia with statistically significant neutrophil oscillations.

Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib

Evidence-based guidelines for the use of tyrosine kinase inhibitors in adults with Philadelphia chromosome-positive or BCR-ABL-positive acute lymphoblastic leukemia: a Canadian consensus

Evolving Therapeutic Options for Polycythemia Vera: Perspectives of the Canadian Myeloproliferative Neoplasms Group

Examining the molecular mechanism of bcl-2 family proteins at membranes by fluorescence spectroscopy

Fornix fibers and motivational states as controllers of behavior: a study stimulated by the contextual retrieval theory

Hand Mirror Cells and Hypercalcemia: A Rare Presentation of Pediatric Acute Lymphoblastic Leukemia

High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells

How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry

ITACA: A new validated international erythropoietic stimulating agent-response score that further refines the predictive power of previous scoring systems

Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence

Increased eculizumab requirements during pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: case report and review of the literature.

Iron overload in myelodysplastic syndromes: Evidence based guidelines from the Canadian consortium on MDS

Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells.

Laboratory Investigation of Myeloproliferative Neoplasms (MPNs): Recommendations of the Canadian Mpn Group

Long-term outcome of a pediatric-inspired regimen used for adults aged 18-50 years with newly diagnosed acute lymphoblastic leukemia.

Mixed variant multicentric Castleman disease treated with rituximab: case report

Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells--Mitochondrial Outer Membrane Permeabilization and Beyond

Molecular genetic basis for the antiidiotypic antibody response associated with successful renal allograft survival in humans

Morphology of acute promyelocytic leukemia with cytogenetic or molecular evidence for the diagnosis: Characterization of additional microgranular variants ⬇️

Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid

Optimizing outcomes with azacitidine: recommendations from Canadian centres of excellence.

Overall survival in lower IPSS risk MDS by receipt of iron chelation therapy, adjusting for patient-related factors and measuring from time of first red blood cell transfusion dependence: an MDS-CAN analysis.

Patient-related factors independently impact overall survival in patients with myelodysplastic syndromes: an MDS-CAN prospective study.

Phase II study of targeted therapy with temozolomide in acute myeloid leukaemia and high-risk myelodysplastic syndrome patients pre-screened for low O(6) -methylguanine DNA methyltransferase expression

Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance.

Randomized phase II comparison of standard CHOP with weekly CHOP in elderly patients with non-Hodgkin's lymphoma ⬇️

Regulating cell death at, on, and in membranes.

Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatm

Sam68 Allows Selective Targeting of Human Cancer Stem Cells

Still embedded together binding to membranes regulates Bcl-2 protein interactions.

Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results.

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

The predictive value of intracellular imatinib levels in newly diagnosed chronic myeloid leukemia

The proapoptotic protein tBid forms both superficially bound and membrane-inserted oligomers.

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation

Treatment of older patients with acute myeloid leukemia (AML): revised Canadian consensus guidelines

Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove

cml biology for the clinician in 2011: six impossible things to believe before breakfast on the way to cure.