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Complex intra-operonic dynamics mediated by a small RNA in Streptomyces coelicolor.

artículo científico publicado en 2014

Crp is a global regulator of antibiotic production in streptomyces

scientific journal article

Discovery of Alternative Producers of the Enediyne Antitumor Antibiotic C-1027 with High Titers.

artículo científico publicado en 2018

Discovery of the leinamycin family of natural products by mining actinobacterial genomes

artículo científico publicado en 2017

Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.

artículo científico publicado en 2014

Engineered production and evaluation of 6'-deoxy-tallysomycin H-1 revealing new insights into the structure-activity relationship of the anticancer drug bleomycin.

artículo científico

Genome Mining of Streptomyces mobaraensis DSM40847 as a Bleomycin Producer Providing a Biotechnology Platform To Engineer Designer Bleomycin Analogues.

artículo científico publicado en 2017

New isofuranonaphthoquinones and isoindolequinones from Streptomyces sp. CB01883.

artículo científico publicado en 2016

P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities

artículo científico publicado en 2018

Regulation of a novel gene cluster involved in secondary metabolite production in Streptomyces coelicolor.

artículo científico publicado en 2010

Resistance to Enediyne Antitumor Antibiotics by Sequestration

artículo científico publicado en 2018

Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2.

artículo científico publicado en 2019

Strain Prioritization and Genome Mining for Enediyne Natural Products

artículo científico publicado en 2016

Strain prioritization for natural product discovery by a high-throughput real-time PCR method.

artículo científico publicado en 2014

Unlocking the trove of metabolic treasures: activating silent biosynthetic gene clusters in bacteria and fungi

scientific article published on 15 April 2019