Lista de obras -

1-Methoxy-3-indolylmethyl DNA adducts in six tissues, and blood protein adducts, in mice under pak choi diet: time course and persistence

scientific article published on 15 April 2019

1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation.

artículo científico publicado en 2010

A photocaged inhibitor of acid sphingomyelinase

artículo científico publicado en 2020

A secondary metabolite of Brassicales, 1-methoxy-3-indolylmethyl glucosinolate, as well as its degradation product, 1-methoxy-3-indolylmethyl alcohol, forms DNA adducts in the mouse, but in varying tissues and cells

artículo científico publicado en 2013

Acid Sphingomyelinase Deficiency Ameliorates Farber Disease ⬇️

artículo científico

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

artículo científico publicado en 2020

Acid sphingomyelinase - a regulator of canonical transient receptor potential channel 6 (TRPC6) activity

artículo científico publicado en 2019

Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide

scientific article published on 23 July 2018

Arsenic-containing hydrocarbons: effects on gene expression, epigenetics, and biotransformation in HepG2 cells.

artículo científico publicado en 2018

Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro

scientific article published on 10 March 2020

Clinical Development of Sphingosine as Anti-Bacterial Drug: Inhalation of Sphingosine in Mini Pigs has no Adverse Side Effects

artículo científico publicado en 2019

Core-multishell nanocarriers enhance drug penetration and reach keratinocytes and antigen-presenting cells in intact human skin

artículo científico publicado en 2019

Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels

artículo científico publicado en 2019

Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS.

artículo científico publicado en 2012

Down-regulation of acid sphingomyelinase and neutral sphingomyelinase-2 inversely determines the cellular resistance to plasmalemmal injury by pore-forming toxins

artículo científico publicado en 2018

Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels

artículo científico publicado en 2017

Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

artículo científico publicado en 2019

Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium.

artículo científico publicado en 2017

Glucosinolates Are Mainly Absorbed Intact in Germfree and Human Microbiota-Associated Mice

artículo científico publicado en 2015

Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation

artículo científico publicado en 2020

In Silico Prediction of Human Sulfotransferase 1E1 Activity Guided by Pharmacophores from Molecular Dynamics Simulations.

artículo científico publicado en 2015

Interleukin-22 protects intestinal stem cells against genotoxic stress

artículo científico publicado en 2019

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis

scientific article published on 19 June 2019

Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium

artículo científico publicado en 2019

Method to simultaneously determine the sphingosine 1-phosphate breakdown product (2E)-hexadecenal and its fatty acid derivatives using isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight mass spectrometry

artículo científico publicado en 2014

Monitoring the Sphingolipid de novo Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry

artículo científico publicado en 2019

Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells

artículo científico publicado en 2021

Optimized enzymatic hydrolysis of DNA for LC-MS/MS analyses of adducts of 1-methoxy-3-indolylmethyl glucosinolate and methyleugenol.

artículo científico publicado en 2012

Pathological manifestations of Farber disease in a new mouse model

artículo científico publicado en 2018

Qualifying X-ray and Stimulated Raman Spectromicroscopy for Mapping Cutaneous Drug Penetration

scientific article published on 15 May 2019

Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis

scientific article published on 15 October 2019

Serine Protease-Mediated Cutaneous Inflammation: Characterization of an Ex Vivo Skin Model for the Assessment of Dexamethasone-Loaded Core Multishell-Nanocarriers

scientific article published on 10 September 2020

Simultaneous detection of multiple DNA adducts in human lung samples by isotope-dilution UPLC-MS/MS

artículo científico publicado en 2014

Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2.

artículo científico publicado en 2018

Sphingosine as a New Antifungal Agent against Candida and Aspergillus spp.

scientific article published in 2022

Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia

artículo científico publicado en 2019

Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery

artículo científico publicado en 2018

The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Injury

scientific article published on 03 July 2019

The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells

artículo científico publicado en 2024

The glucosinolate metabolite 1-methoxy-3-indolylmethyl alcohol induces a gene expression profile in mouse liver similar to the expression signature caused by known genotoxic hepatocarcinogens.

artículo científico publicado en 2015

Use of Acid Ceramidase and Sphingosine Kinase Inhibitors as Antiviral Compounds Against Measles Virus Infection of Lymphocytes in vitro

scientific article published on 01 October 2019

Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice

artículo científico publicado en 2018

Vitamin C in combination with inhibition of mutant IDH1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells

artículo científico publicado en 2019

Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor in colon cancer cells

artículo científico publicado en 2018

Lista de obras de

1-Methoxy-3-indolylmethyl DNA adducts in six tissues, and blood protein adducts, in mice under pak choi diet: time course and persistence

1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation.

A photocaged inhibitor of acid sphingomyelinase

A secondary metabolite of Brassicales, 1-methoxy-3-indolylmethyl glucosinolate, as well as its degradation product, 1-methoxy-3-indolylmethyl alcohol, forms DNA adducts in the mouse, but in varying tissues and cells

Acid Sphingomyelinase Deficiency Ameliorates Farber Disease ⬇️

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

Acid sphingomyelinase - a regulator of canonical transient receptor potential channel 6 (TRPC6) activity

Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide

Arsenic-containing hydrocarbons: effects on gene expression, epigenetics, and biotransformation in HepG2 cells.

Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro

Clinical Development of Sphingosine as Anti-Bacterial Drug: Inhalation of Sphingosine in Mini Pigs has no Adverse Side Effects

Core-multishell nanocarriers enhance drug penetration and reach keratinocytes and antigen-presenting cells in intact human skin

Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels

Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS.

Down-regulation of acid sphingomyelinase and neutral sphingomyelinase-2 inversely determines the cellular resistance to plasmalemmal injury by pore-forming toxins

Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels

Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium.

Glucosinolates Are Mainly Absorbed Intact in Germfree and Human Microbiota-Associated Mice

Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation

In Silico Prediction of Human Sulfotransferase 1E1 Activity Guided by Pharmacophores from Molecular Dynamics Simulations.

Interleukin-22 protects intestinal stem cells against genotoxic stress

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis

Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium

Method to simultaneously determine the sphingosine 1-phosphate breakdown product (2E)-hexadecenal and its fatty acid derivatives using isotope-dilution HPLC-electrospray ionization-quadrupole/time-of-flight mass spectrometry

Monitoring the Sphingolipid de novo Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry

Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells

Optimized enzymatic hydrolysis of DNA for LC-MS/MS analyses of adducts of 1-methoxy-3-indolylmethyl glucosinolate and methyleugenol.

Pathological manifestations of Farber disease in a new mouse model

Qualifying X-ray and Stimulated Raman Spectromicroscopy for Mapping Cutaneous Drug Penetration

Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis

Serine Protease-Mediated Cutaneous Inflammation: Characterization of an Ex Vivo Skin Model for the Assessment of Dexamethasone-Loaded Core Multishell-Nanocarriers

Simultaneous detection of multiple DNA adducts in human lung samples by isotope-dilution UPLC-MS/MS

Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2.

Sphingosine as a New Antifungal Agent against Candida and Aspergillus spp.

Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia

Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery

The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Injury

The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells

The glucosinolate metabolite 1-methoxy-3-indolylmethyl alcohol induces a gene expression profile in mouse liver similar to the expression signature caused by known genotoxic hepatocarcinogens.

Use of Acid Ceramidase and Sphingosine Kinase Inhibitors as Antiviral Compounds Against Measles Virus Infection of Lymphocytes in vitro

Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice

Vitamin C in combination with inhibition of mutant IDH1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells

Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor in colon cancer cells