Lista de obras -

A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.

artículo científico publicado en 2017

Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape

artículo científico publicado en 2017

Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.

artículo científico publicado en 2016

Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis

artículo científico publicado en 2016

Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia

artículo científico publicado en 2019

Clonal evolution of acute myeloid leukemia from diagnosis to relapse

scientific article published on 03 September 2019

Clonal heterogeneity of -ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia

scientific article published on 10 July 2018

Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia

artículo científico publicado en 2016

Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML

artículo científico publicado en 2018

Compatibility of RUNX1/ETO fusion protein modules driving CD34+ human progenitor cell expansion

scientific article published on 09 August 2018

Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus.

artículo científico publicado en 2016

Evolution of cytogenetically normal acute myeloid leukemia during therapy and relapse: An exome sequencing study of 50 patients

artículo científico publicado en 2018

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.

artículo científico publicado en 2013

FAT1 expression and mutations in adult acute lymphoblastic leukemia.

artículo científico publicado en 2014

FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia.

artículo científico publicado en 2011

GATA2 mutations in myeloid malignancies: Two zinc fingers in many pies

artículo científico publicado en 2019

In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components.

artículo científico publicado en 2016

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis

artículo científico

Loss of KDM6A confers drug resistance in acute myeloid leukemia

scientific article published on 14 June 2019

Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients

artículo científico publicado en 2016

Mutational landscape of adult ETP-ALL.

artículo científico publicado en 2013

Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism

artículo científico publicado en 2021

PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia

artículo científico publicado en 2019

Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load

artículo científico publicado en 2018

Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.

artículo científico publicado en 2016

The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS).

artículo científico publicado en 2013

The NPM1 mutation type has no impact on survival in cytogenetically normal AML.

artículo científico publicado en 2014

The clathrin-binding domain of CALM and the OM-LZ domain of AF10 are sufficient to induce acute myeloid leukemia in mice ⬇️

artículo científico publicado el 17 de junio de 2011

The clinical mutatome of core binding factor leukemia

scientific article published on 02 January 2020

The new and recurrent FLT3 juxtamembrane deletion mutation shows a dominant negative effect on the wild-type FLT3 receptor.

artículo científico publicado en 2016

The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.

artículo científico publicado en 2015

The target landscape of clinical kinase drugs

artículo científico publicado en 2017

Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia.

artículo científico publicado en 2017

Up a lymphoid blind alley: Does CALM/AF10 disturb Ikaros during leukemogenesis?

artículo científico publicado en 2011

Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation

artículo científico publicado en 2015

ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.

artículo científico publicado en 2016

ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells

artículo científico publicado en 2020

Lista de obras de

A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.

Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape

Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.

Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis

Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia

Clonal evolution of acute myeloid leukemia from diagnosis to relapse

Clonal heterogeneity of -ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia

Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia

Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML

Compatibility of RUNX1/ETO fusion protein modules driving CD34+ human progenitor cell expansion

Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus.

Evolution of cytogenetically normal acute myeloid leukemia during therapy and relapse: An exome sequencing study of 50 patients

Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.

FAT1 expression and mutations in adult acute lymphoblastic leukemia.

FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia.

GATA2 mutations in myeloid malignancies: Two zinc fingers in many pies

In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components.

Isolated trisomy 13 defines a homogeneous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis

Loss of KDM6A confers drug resistance in acute myeloid leukemia

Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients

Mutational landscape of adult ETP-ALL.

Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism

PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia

Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load

Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.

The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS).

The NPM1 mutation type has no impact on survival in cytogenetically normal AML.

The clathrin-binding domain of CALM and the OM-LZ domain of AF10 are sufficient to induce acute myeloid leukemia in mice ⬇️

The clinical mutatome of core binding factor leukemia

The new and recurrent FLT3 juxtamembrane deletion mutation shows a dominant negative effect on the wild-type FLT3 receptor.

The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.

The target landscape of clinical kinase drugs

Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia.

Up a lymphoid blind alley: Does CALM/AF10 disturb Ikaros during leukemogenesis?

Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation

ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.

ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells