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16alpha-Bromoepiandrosterone (HE2000) limits non-productive inflammation and stimulates immunity in lungs

artículo científico publicado en 2009

5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice

artículo científico publicado en 2010

A potent immunomodulatory compound, (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid, prevents spontaneous and accelerated forms of autoimmune diabetes in NOD mice and inhibits the immunoinflammatory diabetes induced by multiple low doses of strep

artículo científico publicado en 2006

Acceleration of SLE-like syndrome development in NZBxNZW F1 mice by beta-glucan.

artículo científico publicado en 2014

Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling.

artículo científico publicado en 2017

Advances in targeting signal transduction pathways

artículo científico publicado en 2012

Ageing: from inflammation to cancer

artículo científico publicado en 2018

Akt as a therapeutic target in cancer

artículo científico publicado en 2008

Amelioration of experimental allergic neuritis by sodium fusidate (fusidin): suppression of IFN-gamma and TNF-alpha and enhancement of IL-10

scientific article published on 01 September 1999

Anti-inflammatory and immune regulatory properties of 5-androsten-3beta, 17beta-diol (HE2100), and synthetic analogue HE3204: implications for treatment of autoimmune diseases.

artículo científico publicado en 2005

Antibiotic susceptibility of group A streptococci in 2 Italian cities: Milano and Catania

artículo científico publicado en 1997

Antibodies to endothelial cells in primary vasculitides mediate in vitro endothelial cytotoxicity in the presence of normal peripheral blood mononuclear cells.

artículo científico publicado en 1992

Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells

artículo científico publicado en 2010

Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo.

artículo científico publicado en 2008

Apotransferrin inhibits interleukin-2 expression and protects mice from experimental autoimmune encephalomyelitis.

artículo científico publicado en 2013

Applying the FRAD Conceptual Model to an Authority File for Manuscripts: Analysis of a Local Implementation

article by Marielle Veve published 7 January 2009 in Cataloging & Classification Quarterly

Association of chitotriosidase genotype with the development of non-alcoholic fatty liver disease.

artículo científico publicado en 2012

Association of t(14;18) translocation with HCV infection in gastrointestinal MALT lymphomas.

artículo científico publicado en 2008

B9. Tumoricidal activity of GIT-27NO depends on RNS and ROS generation

BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer

artículo científico publicado en 2012

Beneficial effects of r-h-CLU on disease severity in different animal models of peripheral neuropathies

scientific article published on 21 August 2007

Biphasic effect of interferon-gamma in murine collagen-induced arthritis

scientific article published on 01 May 1995

Blood levels of transforming growth factor-beta 1 (TGF-beta1) are elevated in both relapsing remitting and chronic progressive multiple sclerosis (MS) patients and are further augmented by treatment with interferon-beta 1b (IFN-beta1b).

artículo científico publicado en 1998

C20. Novel NO-donation compound GIT-27NO possesses strong tumoricidal capacity in vitro and in vivo

C21. GIT-27 NO may be a potential therapeutic agent for melanoma treatment by inhibition of the transcription repressor YIN-YANG

CD4+ T-cell gene expression of healthy donors, HIV-1 and elite controllers: Immunological chaos.

artículo científico publicado en 2016

Carbon monoxide-releasing molecule-A1 (CORM-A1) improves clinical signs of experimental autoimmune uveoretinitis (EAU) in rats

artículo científico publicado en 2015

Characterization of the Pathophysiological Role of CD47 in Uveal Melanoma

scientific article published on 04 July 2019

Chitotriosidase and inflammatory mediator levels in Alzheimer's disease and cerebrovascular dementia.

artículo científico publicado en 2006

Chitotriosidase gene expression in Kupffer cells from patients with non-alcoholic fatty liver disease

artículo científico publicado en 2006

Chronic Administration of UK-114, a Multifunctional Emerging Protein, Modulates the Th1/Th2 Cytokine Pattern and Experimental Autoimmune Diseases

artículo científico publicado en 1999

Circulating serum levels of IL-1ra in patients with relapsing remitting multiple sclerosis are normal during remission phases but significantly increased either during exacerbations or in response to IFN-beta treatment

scientific article published on 01 May 1996

Combination of cyclophosphamide and interferon-beta halts progression in patients with rapidly transitional multiple sclerosis

artículo científico publicado en 2001

Comparative study of rapamycin and temsirolimus demonstrates superimposable anti-tumour potency on prostate cancer cells.

artículo científico publicado en 2012

Comprehensive Analysis of RNA-Seq Gene Expression Profiling of Brain Transcriptomes Reveals Novel Genes, Regulators, and Pathways in Autism Spectrum Disorder

artículo científico publicado en 2020

Computational Modeling of PI3K/AKT and MAPK Signaling Pathways in Melanoma Cancer

artículo científico publicado en 2016

Concanavalin A-induced hepatitis in mice is prevented by interleukin (IL)-10 and exacerbated by endogenous IL-10 deficiency.

artículo científico publicado en 1999

Contribution of the macrophage migration inhibitory factor superfamily of cytokines in the pathogenesis of preclinical and human multiple sclerosis: In silico and in vivo evidences

artículo científico publicado en 2018

Control of the of the final stage of immune-mediated diabetes by ISO-1, an antagonist of macrophage migration inhibitory factor

Correlation between islet cell antibodies and anti-cytomegalovirus IgM and IgG antibodies in healthy first-degree relatives of type 1 (insulin-dependent) diabetic patients.

artículo científico publicado en 1990

Corrigendum to "Expression of DNA methylation genes in secondary progressive multiple sclerosis" [J. Neuroimmunol. 290 (2016 Jan. 15) 66-9].

artículo científico publicado en 2016

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy

artículo científico publicado en 2016

Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes

artículo científico publicado en 2005

Crude extract of hydatid laminated layer from Echinococcus granulosus cyst attenuates mucosal intestinal damage and inflammatory responses in Dextran Sulfate Sodium induced colitis in mice

artículo científico publicado en 2015

Curative effects of recombinant human Interleukin-6 in DA rats with protracted relapsing experimental allergic encephalomyelitis

artículo científico publicado en 2001

Curative effects of sodium fusidate on the development of dinitrobenzenesulfonic acid-induced colitis in rats

artículo científico publicado en 2003

Cyclin D1 and Ewing's sarcoma/PNET: A microarray analysis

artículo científico publicado en 2015

Cyclin D1 in pediatric neuroblastic tumors: A microarray analysis.

artículo científico publicado en 2015

Cytotoxic and immune-sensitizing properties of nitric oxide-modified Saquinavir in iNOS-positive human melanoma cells.

artículo científico publicado en 2011

Decitabine induces regulatory T cells, inhibits the production of IFN-gamma and IL-17 and exerts preventive and therapeutic efficacy in rodent experimental autoimmune neuritis

artículo científico publicado en 2018

Deoxyspergualin neither counteracts lipopolysaccharide (LPS) or Staphylococcus aureus enterotoxin-B (SEB) induced lethality in mice nor does it modulate the release of tumor necrosis factor-alpha

scientific article published on 01 March 1998

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

artículo científico publicado en 2014

Diagnostic utility of cyclin D1 in the diagnosis of small round blue cell tumors in children and adolescents.

artículo científico publicado en 2016

Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs

artículo científico publicado en 2010

Early prophylaxis with recombinant human interleukin-11 prevents spontaneous diabetes in NOD mice

artículo científico publicado en 1999

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine

artículo científico publicado en 2012

Effect of octreotide on insulin requirement, hepatic glucose production, growth hormone, glucagon and c-peptide levels in type 2 diabetic patients with chronic renal failure or normal renal function.

artículo científico publicado en 2001

Effects of Combined Admistration of Imatinib and Sorafenib in a Murine Model of Liver Fibrosis

scientific article published on 20 September 2020

Effects of NO-Hybridization on the Immunomodulatory Properties of the HIV Protease Inhibitors Lopinavir and Ritonavir

artículo científico publicado en 2015

Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer

artículo científico

Effects of octreotide on glycaemic control, glucose disposal, hepatic glucose production and counterregulatory hormones secretion in type 1 and type 2 insulin treated diabetic patients

artículo científico publicado en 1997

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

artículo científico publicado en 2017

Effects of the immunomodulator, VGX-1027, in endotoxin-induced uveitis in Lewis rats.

artículo científico publicado en 2008

Effects of tumour necrosis factor-alpha on human sperm motility and apoptosis

scientific article published on 17 February 2007

Elevated Serum Levels of Osteopontin in HCV-Associated Lymphoproliferative Disorders.

artículo científico publicado en 2005

Elevated serum levels of interleukin-12 in chronic progressive multiple sclerosis

artículo científico publicado en 1996

Emerging MEK inhibitors.

artículo científico publicado en 2010

Emerging Neurological and Psychobiological Aspects of COVID-19 Infection

scientific article published on 12 November 2020

Emerging Raf inhibitors.

artículo científico publicado en 2009

Emerging Role of the Macrophage Migration Inhibitory Factor Family of Cytokines in Neuroblastoma. Pathogenic Effectors and Novel Therapeutic Targets?

scientific article published on 06 March 2020

Emerging therapeutic targets for the treatment of hepatic fibrosis

artículo científico publicado en 2015

Endogenous interleukin-12 only plays a key pathogenetic role in non-obese diabetic mouse diabetes during the very early stages of the disease

artículo científico publicado en 1999

Endothelial activation by aPL: a potential pathogenetic mechanism for the clinical manifestations of the syndrome

artículo científico publicado en 2000

Enhanced percentage of CD5+ B lymphocytes in newly diagnosed IDDM patients

artículo científico publicado en 1990

Enhanced percentage of Leu M3+DR+ and Leu M3+CD25+ cells in newly diagnosed IDDM patients

artículo científico publicado en 1991

Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy

artículo científico publicado en 2010

Essential pathogenetic role for interferon (IFN-)gamma in concanavalin A-induced T cell-dependent hepatitis: exacerbation by exogenous IFN-gamma and prevention by IFN-gamma receptor-immunoglobulin fusion protein

artículo científico publicado en 2000

Essential pathogenic role for endogenous interferon-gamma (IFN-gamma) during disease onset phase of murine experimental autoimmune orchitis. I. In vivo studies

scientific article published on 01 March 1998

Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL-18-binding protein: Fc construct

artículo científico publicado en 2003

Evaluation of hyaluronic acid-P40 conjugated cream in a mouse model of dermatitis induced by oxazolone.

artículo científico publicado en 2017

Exacerbation of protracted-relapsing experimental allergic encephalomyelitis in DA rats by gluten-free diet

artículo científico publicado en 2004

Exploiting p53 status to enhance effectiveness of chemotherapy by lowering associated toxicity

artículo científico publicado en 2011

Exploratory Analysis of iPSCS-Derived Neuronal Cells as Predictors of Diagnosis and Treatment of Alzheimer Disease

artículo científico publicado en 2020

Extracellular lysosome-associated membrane protein-1 (LAMP-1) mediates autoimmune disease progression in the NOD model of type 1 diabetes

artículo científico publicado en 2005

Extrahepatic disorders of HCV infection: a distinct entity of B-cell neoplasia?

artículo científico publicado en 2010

FK-506 prevents diabetes in diabetes-prone BB/Wor rats

artículo científico publicado en 1991

Failure of exogenously administered interferon-gamma or blockage of endogenous interleukin-4 with specific inhibitors to augment the incidence of autoimmune diabetes in male NOD mice

artículo científico publicado en 1999

Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1.

artículo científico publicado en 2016

Food toxicology: quantitative analysis of the research field literature

scientific article published on 29 May 2019

Fusidic acid and insulin-dependent diabetes mellitus

artículo científico publicado en 1996

GSK-3 as potential target for therapeutic intervention in cancer

artículo científico publicado en 2014

Gasotransmitters and the immune system: Mode of action and novel therapeutic targets

artículo científico publicado en 2018

Genetic differences in immune reactivity to mercuric chloride (HgCl2): immunosuppression of H-2d mice is mediated by interferon-gamma (IFN-gamma)

scientific article published on 01 July 1997

HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression.

artículo científico publicado en 2010

HE3286, an orally bioavailable synthetic analogue of an active DHEA metabolite suppresses spontaneous autoimmune diabetes in the non-obese diabetic (NOD) mouse

artículo científico publicado en 2011

HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease

artículo científico publicado en 2009

HIV-protease inhibitors for the treatment of cancer: Repositioning HIV protease inhibitors while developing more potent NO-hybridized derivatives?

artículo científico publicado en 2016

Heme oxygenase-1 expression in peripheral blood mononuclear cells correlates with disease activity in multiple sclerosis

artículo científico publicado en 2013

Human anticardiolipin monoclonal autoantibodies cause placental necrosis and fetal loss in BALB/c mice

artículo científico publicado en 1998

Hypomethylating Agent 5-Aza-2′-deoxycytidine (DAC) Ameliorates Multiple Sclerosis in Mouse Models

scientific article published on 01 December 2014

IL-18 binding protein fusion construct delays the development of diabetes in adoptive transfer and cyclophosphamide-induced diabetes in NOD mouse

artículo científico publicado en 2005

ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis

artículo científico publicado en 2005

Identification of novel chemotherapeutic strategies for metastatic uveal melanoma.

artículo científico publicado en 2017

Identification of novel targets for the diagnosis and treatment of liver fibrosis.

artículo científico

Immune-Modulating Drug MP1032 with SARS-CoV-2 Antiviral Activity In Vitro: A potential Multi-Target Approach for Prevention and Early Intervention Treatment of COVID-19

artículo científico publicado en 2020

Immunomodulation of murine experimental SLE-like disease by interferon-gamma

artículo científico publicado en 1998

Immunosuppressive activity of 15-deoxyspergualin on normal and autoimmune peripheral blood mononuclear cells

artículo científico publicado en 1996

Impaired Expression of Tetraspanin 32 (TSPAN32) in Memory T Cells of Patients with Multiple Sclerosis

artículo científico publicado en 2020

In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells.

artículo científico publicado en 2011

In vitro inhibition of enterobacteria-reactive CD4+CD25- T cells and suppression of immunoinflammatory colitis in mice by the novel immunomodulatory agent VGX-1027.

artículo científico publicado en 2008

In vitro type-1 and type-2 cytokine production in systemic lupus erythematosus: lack of relationship with clinical disease activity

artículo científico publicado en 1996

In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: Modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models

article

In vivo treatment with a monoclonal antibody to interferon-gamma neither affects the survival nor the incidence of lupus-nephritis in the MRL/lpr-lpr mouse

artículo científico publicado en 1992

Increased rate of survival in Streptococcus pneumoniae-infected rats treated with the new immunomodulator Pidotimod

artículo científico publicado en 1992

Increased serum levels of interleukin-18 in patients with multiple sclerosis

scientific article published on 01 July 2001

Induction of OAS gene family in HIV monocyte infected patients with high and low viral load.

artículo científico publicado en 2016

Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO.

artículo científico publicado en 2010

Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin

artículo científico publicado en 2009

Insulin lispro is as effective as regular insulin in optimising metabolic control and preserving beta-cell function at onset of type 1 diabetes mellitus

artículo científico publicado en 2003

Interleukin (IL)-1beta toxicity to islet beta cells: Efaroxan exerts a complete protection.

artículo científico publicado en 2005

Interleukin-13 prevents autoimmune diabetes in NOD mice

artículo científico publicado en 1999

Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells

artículo científico publicado en 2011

Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy

artículo científico publicado en 2011

Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance

artículo científico publicado en 2008

Involvement of the Nrf2/HO-1/CO axis and therapeutic intervention with the CO-releasing molecule CORM-A1, in a murine model of autoimmune hepatitis.

artículo científico publicado en 2017

MFP14, a multifunctional emerging protein with immunomodulatory properties, prevents spontaneous and recurrent autoimmune diabetes in NOD mice

artículo científico publicado en 2001

MIF in autoimmunity and novel therapeutic approaches.

scientific article published on 20 August 2008

Macrophage Migration Inhibitory Factor (MIF) and Its Homologue d-Dopachrome Tautomerase (DDT) Inversely Correlate with Inflammation in Discoid Lupus Erythematosus

artículo científico publicado en 2021

Macrophage migration inhibitory factor (MIF) is necessary for progression of autoimmune diabetes mellitus

artículo científico publicado en 2008

Macrophage migration inhibitory factor (MIF) seems crucially involved in Guillain–Barré syndrome and experimental allergic neuritis

artículo científico publicado en 2005

Macrophage-derived cytokines in the follicular fluids of women with infertility due to immunological causes. Elevated levels of interleukin 6 and low levels of granulocyte-macrophage colony-stimulating factor

artículo científico publicado en 1998

Meta-Analysis of Transcriptomic Data of Dorsolateral Prefrontal Cortex and of Peripheral Blood Mononuclear Cells Identifies Altered Pathways in Schizophrenia

scientific article published on 03 April 2020

Modulation of Tetraspanin 32 (TSPAN32) Expression in T Cell-Mediated Immune Responses and in Multiple Sclerosis

scientific article published on 04 September 2019

Modulation of heat shock proteins during macrophage differentiation.

artículo científico publicado en 2012

Molecular mechanisms involved in NAFLD progression

scientific article published on 08 April 2009

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

artículo científico publicado en 2014

Murine concanavalin A-induced hepatitis is prevented by interleukin 12 (IL-12) antibody and exacerbated by exogenous IL-12 through an interferon-gamma-dependent mechanism

scientific article published on 01 October 2000

Naturally occurring compounds in differentiation based therapy of cancer

artículo científico publicado en 2018

Neuroprotective Mechanisms of Three Natural Antioxidants on a Rat Model of Parkinson's Disease: A Comparative Study

scientific article published on 06 January 2020

New perspectives in HCV therapy: entry inhibitors.

artículo científico publicado en 2010

No-Modified Saquinavir is Equally Efficient Against Doxorubicin Sensitive and Resistant Non-Small Cell Lung Carcinoma Cells / MODIFIKOVANA KOVANA FORMA SAKVINAVIRA EFIKASNO SU PRIMI RA RAST ĆELIJA NESITNOĆELIJSKOG KARCINOMA PLUĆA RAZLIČITE OSETUI

artículo científico publicado en 2013

Nondepleting anti-CD4 and soluble interleukin-1 receptor prevent autoimmune destruction of syngeneic islet grafts in diabetic NOD mice

artículo científico publicado en 2002

Novel components of the human metabolome: The identification, characterization and anti-inflammatory activity of two 5-androstene tetrols

artículo científico publicado en 2010

Novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide (GIT-27NO) induces p53 mediated apoptosis in human A375 melanoma cells.

artículo científico publicado en 2008

Oral Delivery of Particulate Transforming Growth Factor Beta 1 and All-Trans Retinoic Acid Reduces Gut Inflammation in Murine Models of Inflammatory Bowel Disease

artículo científico publicado en 2015

Oral treatment with HE3286 ameliorates disease in rodent models of rheumatoid arthritis

artículo científico publicado en 2010

Overexpression of Macrophage Migration Inhibitory Factor and Its Homologue D-Dopachrome Tautomerase as Negative Prognostic Factor in Neuroblastoma

artículo científico publicado en 2019

Overexpression of macrophage migration inhibitory factor and functionally-related genes, D-DT, CD74, CD44, CXCR2 and CXCR4, in glioblastoma

artículo científico publicado en 2018

PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches

artículo científico publicado en 2009

Parkinson’s disease is associated with increased serum levels of macrophage migration inhibitory factor

artículo científico publicado en 2011

Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach.

artículo científico publicado en 2018

Pharmacological application of carbon monoxide ameliorates islet-directed autoimmunity in mice via anti-inflammatory and anti-apoptotic effects.

artículo científico publicado en 2014

Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome.

artículo científico publicado en 2011

Phase II study of the antiretroviral activity and safety of the glucocorticoid receptor antagonist mifepristone in HIV-1-infected patients

article

Physiologically based microenvironment for in vitro neural differentiation of adipose-derived stem cells.

artículo científico publicado en 2018

Placental thrombosis and fetal loss after passive transfer of mouse lupus monoclonal or human polyclonal anti-cardiolipin antibodies in pregnant naive BALB/c mice

artículo científico publicado en 1995

Potential use of rapamycin in HIV infection

artículo científico publicado en 2010

Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis

artículo científico publicado en 2018

Prevalence of hepatitis C virus infection among health-care workers: A 10-year survey.

artículo científico publicado en 2010

Prevention and treatment of lethal murine endotoxemia by the novel immunomodulatory agent MFP-14.

artículo científico publicado en 2001

Prevention by rolipram of concanavalin A-induced T-cell-dependent hepatitis in mice

artículo científico publicado en 1999

Prevention of carrageenan-induced pleurisy in mice by anti-CD30 ligand monoclonal antibody

artículo científico publicado en 2004

Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1.

artículo científico publicado en 2011

Prevention of diabetes in BB/Wor rats treated with monoclonal antibodies to interferon-gamma

artículo científico publicado en 1990

Prevention of endotoxin-induced lethality in neonatal mice by interleukin-13

scientific article published on 01 June 1997

Prevention of murine experimental autoimmune orchitis by recombinant human interleukin-6

artículo científico publicado en 2002

Preventive and curative effects of cyclophosphamide in an animal model of Guillain Barrè syndrome

scientific article published on 02 May 2008

Primary antiphospholipid syndrome and antiphospholipid syndrome associated to systemic lupus: Are they different entities?

artículo científico publicado en 2018

Proinflammatory effects of exogenously administered IL-10 in experimental autoimmune orchitis.

artículo científico publicado en 2003

Protection from concanavalin A (Con A)-induced T cell-dependent hepatic lesions and modulation of cytokine release in mice by sodium fusidate

artículo científico publicado en 1997

Protection from experimental autoimmune diabetes in the non-obese diabetic mouse with soluble interleukin-1 receptor

scientific article published on 01 August 1994

Protection from experimental autoimmune thyroiditis in CBA mice with the novel immunosuppressant deoxyspergualin

scientific article published on 01 March 1994

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance

artículo científico publicado en 2012

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

artículo científico publicado en 2011

Resistance to TRAIL and how to surmount it.

artículo científico

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

artículo científico publicado en 2016

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

artículo científico publicado en 2011

Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.

artículo científico publicado en 2011

Safety, bioavailability, and pharmacokinetics of VGX-1027-A novel oral anti-inflammatory drug in healthy human subjects

artículo científico publicado en 2015

Saquinavir-NO Inhibits IL-6 Production in Macrophages

article

Saquinavir-NO inhibits S6 kinase activity, impairs secretion of the encephalytogenic cytokines interleukin-17 and interferon-gamma and ameliorates experimental autoimmune encephalomyelitis.

artículo científico publicado en 2013

Saquinavir-NO-targeted S6 protein mediates sensitivity of androgen-dependent prostate cancer cells to TRAIL.

artículo científico publicado en 2012

Senescence as a main mechanism of Ritonavir and Ritonavir-NO action against melanoma

artículo científico publicado en 2019

Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease

artículo científico publicado en 2002

Serum levels of the interferon-gamma-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type I diabetes

scientific article published on 01 March 2001

Short-term prophylaxis with deoxyspergualin prevents testicular autoimmunity in mice

artículo científico publicado en 2002

Short-term treatment of relapsing remitting multiple sclerosis patients with interferon (IFN)-beta1B transiently increases the blood levels of interleukin (IL)-6, IL-10 and IFN-gamma without significantly modifying those of IL-1beta, IL-2, IL-4 and

scientific article published on 01 June 2000

Sodium fusidate ameliorates the course of diabetes induced in mice by multiple low doses of streptozotocin

scientific article published on 01 December 2000

Sodium fusidate and increased remission rate of insulin-dependent diabetes mellitus

artículo científico publicado en 1991

Sodium fusidate in Gillain-Barré syndrome: a case report ⬇️

artículo científico publicado en 1998

Specific and strain-independent effects of dexamethasone in the prevention and treatment of experimental autoimmune encephalomyelitis in rodents

artículo científico publicado en 2010

Standardized bovine colostrum derivative impedes development of type 1 diabetes in rodents.

artículo científico publicado en 2016

Synergistic effect of deoxyspergualin (DSP) and cyclosporin A (CsA) in the prevention of spontaneous autoimmune diabetes in BB rats

scientific article published on 01 August 1996

Targeting breast cancer initiating cells: advances in breast cancer research and therapy

artículo científico publicado en 2014

Targeting the cancer initiating cell: the ultimate target for cancer therapy.

artículo científico publicado en 2012

Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

artículo científico publicado en 2008

Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway

artículo científico publicado en 2011

The Dichotomic Role of Macrophage Migration Inhibitory Factor in Neurodegeneration

artículo científico publicado en 2020

The NO-modified HIV protease inhibitor as a valuable drug for hematological malignancies: Role of p70S6K.

artículo científico publicado en 2015

The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy

artículo científico publicado en 2010

The Role of Macrophages in Neuroinflammatory and Neurodegenerative Pathways of Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis: Pathogenetic Cellular Effectors and Potential Therapeutic Targets.

artículo científico publicado en 2018

The analysis of IL-1 beta and its naturally occurring inhibitors in multiple sclerosis: The elevation of IL-1 receptor antagonist and IL-1 receptor type II after steroid therapy

artículo científico publicado en 2009

The antiinflammatory cytokine interleukin-13 is not detectable in the circulation of multiple sclerosis patients and is not inducible by interferon-beta1b treatment, that neither modifies its ex vivo secretion from peripheral blood mononuclear cells

scientific article published on 01 December 2000

The antitumor properties of a nontoxic, nitric oxide-modified version of saquinavir are independent of Akt.

artículo científico publicado en 2009

The effects of a monoclonal antibody to interferon-gamma on experimental autoimmune thyroiditis (EAT): prevention of disease and decrease of EAT-specific T cells

scientific article published on 01 January 1993

The effects of deoxyspergualin on the development of diabetes in diabetes-prone BB rats

artículo científico publicado en 1992

The immunobiology of apotransferrin in type 1 diabetes

artículo científico publicado en 2012

The involvement of IL-12 in murine experimentally induced autoimmune thyroid disease

scientific article published on 01 June 1999

The neuropathic pain: An overview of the current treatment and future therapeutic approaches

The new and less toxic protease inhibitor saquinavir-NO maintains anti-HIV-1 properties in vitro indistinguishable from those of the parental compound saquinavir

artículo científico publicado en 2011

The novel NO-donating compound GIT-27NO inhibits in vivo growth of human prostate cancer cells and prevents murine immunoinflammatory hepatitis

artículo científico publicado en 2009

The second-to-fourth digit ratio correlates with the rate of academic performance in medical school students.

artículo científico publicado en 2011

The therapeutic potential of mTOR inhibitors in breast cancer

artículo científico publicado en 2016

Therapeutic potential of carbon monoxide in multiple sclerosis

artículo científico publicado en 2012

Therapeutic potential of nitric oxide-modified drugs in colon cancer cells

artículo científico publicado en 2012

Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.

artículo científico publicado en 2011

Transcriptomic Analysis Reveals Abnormal Expression of Prion Disease Gene Pathway in Brains from Patients with Autism Spectrum Disorders

scientific article published on 29 March 2020

Transcriptomic Analysis Reveals Involvement of the Macrophage Migration Inhibitory Factor Gene Network in Duchenne Muscular Dystrophy

scientific article published on 18 November 2019

Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells.

artículo científico publicado en 2009

Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells

artículo científico publicado en 2012

VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus

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Vaccination with IL-6 analogues induces autoantibodies to IL-6 and influences experimentally induced inflammation

article by Pia Galle et al published December 2007 in International Immunopharmacology

Variable effects of cyclophosphamide in rodent models of experimental allergic encephalomyelitis

artículo científico publicado en 2009

Vitamin D3: a helpful immuno-modulator

artículo científico

Yin Yang 1 overexpression in diffuse large B-cell lymphoma is associated with B-cell transformation and tumor progression

artículo científico publicado en 2010

mTOR as a multifunctional therapeutic target in HIV infection.

artículo científico publicado en 2011

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