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Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.

artículo científico publicado en 2016

Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors

artículo científico publicado en 2014

Allosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin.

artículo científico publicado en 2016

An update on recent patents on thrombin inhibitors (2010 - 2013)

artículo científico publicado en 2014

Antigenic Pressure on H3N2 Influenza Virus Drift Strains Imposes Constraints on Binding to Sialylated Receptors but Not Phosphorylated Glycans

scientific article published on 29 October 2019

Chemoenzymatically prepared heparan sulfate containing rare 2-O-sulfonated glucuronic acid residues.

artículo científico publicado en 2015

Comparative analysis of INLIGHT™-labeled enzymatically depolymerized heparin by reverse-phase chromatography and high-performance mass spectrometry

artículo científico publicado en 2016

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin-NO Biochemistry

artículo científico publicado en 2015

Designing Allosteric Regulators of Thrombin. Exosite 2 Features Multiple Subsites That Can Be Targeted by Sulfated Small Molecules for Inducing Inhibition

artículo científico publicado en 2013

GLAD: GLycan Array Dashboard, a visual analytics tool for glycan microarrays

scientific article published on 01 September 2019

GlyGen: Computational and Informatics Resources for Glycoscience

artículo científico publicado en 2020

Interaction of Thrombin with Sucrose Octasulfate

artículo científico publicado en 2011

Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold.

artículo científico publicado en 2012

Rational design of potent, small, synthetic allosteric inhibitors of thrombin

artículo científico publicado en 2011

Substantial non-electrostatic forces are needed to induce allosteric disruption of thrombin's active site through exosite 2.

artículo científico publicado en 2014

Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa

artículo científico publicado en 2013

Targeting the GPIbα binding site of thrombin to simultaneously induce dual anticoagulant and antiplatelet effects

artículo científico publicado en 2014

Tools for generating and analyzing glycan microarray data

scientific article published on 10 September 2020