Lista de obras - Carole A. Bewley - Dominio Público Uruguay

A Model of Peptide Triazole Entry Inhibitor Binding to HIV-1 gp120 and the Mechanism of Bridging Sheet Disruption ⬇️

artículo científico publicado el 22 de marzo de 2013

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

artículo científico publicado en 2018

A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter.

artículo científico publicado en 2017

Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 [...]

artículo científico publicado en 2009

Antimicrobial Chrysophaentin Analogs Identified from Laboratory Cultures of the Marine Microalga Chrysophaeum taylorii

scientific article published on 09 January 2019

Batzelline D and isobatzelline E from the indopacific sponge Zyzzya fuliginosa

artículo científico publicado en 2002

Binding Site Geometry and Subdomain Valency Control Effects of Neutralizing Lectins on HIV-1 Viral Particles.

artículo científico publicado en 2016

Binding of HIV-1 gp41-directed neutralizing and non-neutralizing fragment antibody binding domain (Fab) and single chain variable fragment (ScFv) antibodies to the ectodomain of gp41 in the pre-hairpin and six-helix bundle conformations

artículo científico publicado en 2014

Characterizing carbohydrate-protein interactions by nuclear magnetic resonance spectroscopy.

scientific article published on October 2013

Chemical and Biophysical Approaches for Complete Characterization of Lectin-Carbohydrate Interactions.

artículo científico publicado en 2017

Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ.

artículo científico publicado en 2010

Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria

artículo científico publicado en 2013

Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

artículo científico publicado en 2016

Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis

artículo científico publicado en 2012

Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry

artículo científico publicado en 2016

Design of HIV Coreceptor Derived Peptides That Inhibit Viral Entry at Submicromolar Concentrations.

artículo científico publicado en 2017

Design of an expression system for detecting folded protein domains and mapping macromolecular interactions by NMR ⬇️

artículo científico publicado el 1 de noviembre de 1997

Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor ⬇️

artículo científico publicado el 5 de enero de 2012

Effective isotope labeling of proteins in a mammalian expression system.

artículo científico publicado en 2015

Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle

artículo científico publicado en 2021

Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments.

artículo científico publicado en 2012

Glycopeptide mimetics recapitulate high-mannose-type oligosaccharide binding and function.

artículo científico publicado en 2015

Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential

artículo científico publicado en 2016

HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth

artículo científico publicado en 2015

Inhibition of hepatitis C virus by the cyanobacterial protein Microcystis viridis lectin: mechanistic differences between the high-mannose specific lectins MVL, CV-N, and GNA.

artículo científico publicado en 2013

Insights from NMR Spectroscopy into the Conformational Properties of Man-9 and Its Recognition by Two HIV Binding Proteins.

artículo científico publicado en 2017

Lithistid Sponges: Star Performers or Hosts to the Stars

artículo científico publicado en 1998

Mammalian expression of isotopically labeled proteins for NMR spectroscopy

artículo científico

Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy.

artículo científico publicado en 2011

Marine sponge alkaloids as a source of anti-bacterial adjuvants.

artículo científico publicado en 2016

Metabolism and Bioactivation of Fluorochloridone, a Novel Selective Herbicide, in Vivo and in Vitro.

artículo científico publicado en 2016

Mirabamides E-H, HIV-inhibitory depsipeptides from the sponge Stelletta clavosa ⬇️

artículo científico publicado en 2011

Motualevic acids and analogs: synthesis and antimicrobial structure-activity relationships

artículo científico publicado en 2010

NMR spectroscopy of HIV-1 gp120 outer domain.

artículo científico publicado en 2012

Natural products: Tapping into personalized chemistry.

artículo científico publicado en 2018

Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.

artículo científico publicado en 2016

Potent SIV-specific Antibodies Targeting the Cyanovirin Binding Site.

artículo científico publicado en 2014

Solution Conformations of Mycothiol Bimane, 1-d-GlcNAc-α- (1 → 1)-d-myo-Ins and 1-d-GlcNAc-α-(1 → 1)-l-myo-Ins ⬇️

artículo científico publicado el 2 de mayo de 2003

Solution structure of cyanovirin-N, a potent HIV-inactivating protein

artículo científico publicado el 1 de julio de 1998

Structural Basis for Norovirus Inhibition and Fucose Mimicry by Citrate

artículo científico publicado en 2012

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

artículo científico publicado en 2013

Structural comparison of somatically related PG9 and PG16 in complex with their epitope reveals differences in glycan recognition.

artículo científico publicado en 2012

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

artículo científico publicado en 2011

Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry

artículo científico publicado en 2011

Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors ⬇️

artículo científico publicado el 17 de febrero de 2011

Synergistic therapeutic effect of cisplatin and phosphatidylinositol 3-kinase (PI3K) inhibitors in cancer growth and metastasis of Brca1 mutant tumors.

artículo científico publicado en 2014

Synthesis of 9-Dechlorochrysophaentin A Enables Studies Revealing Bacterial Cell Wall Biosynthesis Inhibition Phenotype in B. subtilis

scientific article published on 08 September 2020

Synthesis of novel cyclic NGR/RGD peptide analogs via on resin click chemistry ⬇️

artículo científico publicado el 21 de octubre de 2010

Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

artículo científico publicado en 2016

The Structure of U17 Isolated from Streptomyces clavuligerus and its Properties as an Antioxidant Thiol ⬇️

artículo científico publicado el 1 de junio de 1995

The solution structure of an HMG-I(Y)–DNA complex defines a new architectural minor groove binding motif

artículo científico publicado el 1 de agosto de 1997

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

artículo científico publicado en 2016

Tulongicin, an Antibacterial Tri-Indole Alkaloid from a Deep-Water Topsentia sp. Sponge

artículo científico publicado en 2017

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

artículo científico publicado en 2012

Unprecedented glycosidase activity at a lectin carbohydrate-binding site exemplified by the cyanobacterial lectin MVL.

artículo científico publicado en 2009

X-ray Crystallography and Unexpected Chiroptical Properties Reassign the Configuration of Haliclonadiamine

scientific article published on 30 January 2020

Lista de obras de Carole A. Bewley

A Model of Peptide Triazole Entry Inhibitor Binding to HIV-1 gp120 and the Mechanism of Bridging Sheet Disruption ⬇️

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter.

Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 [...]

Antimicrobial Chrysophaentin Analogs Identified from Laboratory Cultures of the Marine Microalga Chrysophaeum taylorii

Batzelline D and isobatzelline E from the indopacific sponge Zyzzya fuliginosa

Binding Site Geometry and Subdomain Valency Control Effects of Neutralizing Lectins on HIV-1 Viral Particles.

Binding of HIV-1 gp41-directed neutralizing and non-neutralizing fragment antibody binding domain (Fab) and single chain variable fragment (ScFv) antibodies to the ectodomain of gp41 in the pre-hairpin and six-helix bundle conformations

Characterizing carbohydrate-protein interactions by nuclear magnetic resonance spectroscopy.

Chemical and Biophysical Approaches for Complete Characterization of Lectin-Carbohydrate Interactions.

Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ.

Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria

Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis

Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry

Design of HIV Coreceptor Derived Peptides That Inhibit Viral Entry at Submicromolar Concentrations.

Design of an expression system for detecting folded protein domains and mapping macromolecular interactions by NMR ⬇️

Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor ⬇️

Effective isotope labeling of proteins in a mammalian expression system.

Genome-Guided Discovery of Natural Products through Multiplexed Low-Coverage Whole-Genome Sequencing of Soil Actinomycetes on Oxford Nanopore Flongle

Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments.

Glycopeptide mimetics recapitulate high-mannose-type oligosaccharide binding and function.

Griffithsin: An Antiviral Lectin with Outstanding Therapeutic Potential

HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth

Inhibition of hepatitis C virus by the cyanobacterial protein Microcystis viridis lectin: mechanistic differences between the high-mannose specific lectins MVL, CV-N, and GNA.

Insights from NMR Spectroscopy into the Conformational Properties of Man-9 and Its Recognition by Two HIV Binding Proteins.

Lithistid Sponges: Star Performers or Hosts to the Stars

Mammalian expression of isotopically labeled proteins for NMR spectroscopy

Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy.

Marine sponge alkaloids as a source of anti-bacterial adjuvants.

Metabolism and Bioactivation of Fluorochloridone, a Novel Selective Herbicide, in Vivo and in Vitro.

Mirabamides E-H, HIV-inhibitory depsipeptides from the sponge Stelletta clavosa ⬇️

Motualevic acids and analogs: synthesis and antimicrobial structure-activity relationships

NMR spectroscopy of HIV-1 gp120 outer domain.

Natural products: Tapping into personalized chemistry.

Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.

Potent SIV-specific Antibodies Targeting the Cyanovirin Binding Site.

Solution Conformations of Mycothiol Bimane, 1-d-GlcNAc-α- (1 → 1)-d-myo-Ins and 1-d-GlcNAc-α-(1 → 1)-l-myo-Ins ⬇️

Solution structure of cyanovirin-N, a potent HIV-inactivating protein

Structural Basis for Norovirus Inhibition and Fucose Mimicry by Citrate

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

Structural comparison of somatically related PG9 and PG16 in complex with their epitope reveals differences in glycan recognition.

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry

Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors ⬇️

Synergistic therapeutic effect of cisplatin and phosphatidylinositol 3-kinase (PI3K) inhibitors in cancer growth and metastasis of Brca1 mutant tumors.

Synthesis of 9-Dechlorochrysophaentin A Enables Studies Revealing Bacterial Cell Wall Biosynthesis Inhibition Phenotype in B. subtilis

Synthesis of novel cyclic NGR/RGD peptide analogs via on resin click chemistry ⬇️

Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

The Structure of U17 Isolated from Streptomyces clavuligerus and its Properties as an Antioxidant Thiol ⬇️

The solution structure of an HMG-I(Y)–DNA complex defines a new architectural minor groove binding motif

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Tulongicin, an Antibacterial Tri-Indole Alkaloid from a Deep-Water Topsentia sp. Sponge

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

Unprecedented glycosidase activity at a lectin carbohydrate-binding site exemplified by the cyanobacterial lectin MVL.

X-ray Crystallography and Unexpected Chiroptical Properties Reassign the Configuration of Haliclonadiamine