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1 H MAS NMR Spectroscopy of Tissues

A Functional Analysis of Mouse Models of Cardiac Disease through Metabolic Profiling

scientific article published in Journal of Biological Chemistry

A Metadata description of the data in "A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.".

artículo científico publicado en 2011

A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study

artículo científico publicado en 2017

A combined 1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR-alpha null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome

artículo científico publicado en 2006

A combined metabolomic and proteomic investigation of the effects of a failure to express dystrophin in the mouse heart

artículo científico publicado en 2008

A gender-specific discriminator in Sprague-Dawley rat urine: the deployment of a metabolic profiling strategy for biomarker discovery and identification.

artículo científico publicado en 2006

A matter of fat: an introduction to lipidomic profiling methods

artículo científico publicado en 2008

A metabolomic and multivariate statistical process to assess the effects of genotoxins in Saccharomyces cerevisiae

artículo científico publicado en 2009

A metabolomic comparison of mouse models of the Neuronal Ceroid Lipofuscinoses

artículo científico publicado en 2011

A metabolomic study of brain tissues from aged mice with low expression of the vesicular monoamine transporter 2 (VMAT2) gene

artículo científico publicado en 2007

A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease

artículo científico publicado en 2010

A metabolomics investigation of non-genotoxic carcinogenicity in the rat.

artículo científico publicado en 2013

A new role for lipocalin prostaglandin d synthase in the regulation of brown adipose tissue substrate utilization.

artículo científico publicado en 2012

A practical guide to metabolomic profiling as a discovery tool for human heart disease ⬇️

artículo científico publicado el 8 de diciembre de 2012

A role for vaccinia virus protein C16 in reprogramming cellular energy metabolism

artículo científico publicado en 2014

A targeted metabolomics assay for cardiac metabolism and demonstration using a mouse model of dilated cardiomyopathy

artículo científico publicado en 2016

Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance

artículo científico publicado en 2015

Alterations in endo-lysosomal function induce similar hepatic lipid profiles in rodent models of drug-induced phospholipidosis and Sandhoff disease

artículo científico publicado en 2017

An integrated functional genomic study of acute phenobarbital exposure in the rat

artículo científico publicado en 2010

Application of a Bayesian deconvolution approach for high-resolution (1)H NMR spectra to assessing the metabolic effects of acute phenobarbital exposure in liver tissue.

artículo científico publicado en 2010

Applications of metabolomics for understanding the action of peroxisome proliferator-activated receptors (PPARs) in diabetes, obesity and cancer

artículo científico publicado en 2012

Applications of metabolomics to understanding obesity in mouse and man.

artículo científico publicado en 2007

Association between sucrose intake and risk of overweight and obesity in a prospective sub-cohort of the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk)

artículo científico publicado en 2015

Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study

artículo científico publicado en 2016

Biomarkers of food intake and metabolite differences between plasma and red blood cell matrices; a human metabolomic profile approach

artículo científico publicado en 2013

Blood triacylglycerols: a lipidomic window on diet and disease

artículo científico publicado en 2016

Brown Adipose Tissue Thermogenic Capacity Is Regulated by Elovl6.

artículo científico publicado en 2015

COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

artículo científico publicado en 2015

Changes in plasma phospholipid fatty acid profiles over 13 years and correlates of change: European Prospective Investigation into Cancer and Nutrition-Norfolk Study

Comparative metabolomics of estrogen receptor positive and estrogen receptor negative breast cancer: alterations in glutamine and beta-alanine metabolism

artículo científico publicado en 2013

Comprehensive Metabolic Profiling of Age-Related Mitochondrial Dysfunction in the High-Fat-Fed ob/ob Mouse Heart

artículo científico publicado en 2015

Computational tools and workflows in metabolomics: An international survey highlights the opportunity for harmonisation through Galaxy

artículo científico publicado en 2017

Current challenges in metabolomics for diabetes research: a vital functional genomic tool or just a ploy for gaining funding?

artículo científico publicado en 2008

DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome

artículo científico publicado en 2010

Deletion of btn1, an orthologue of CLN3, increases glycolysis and perturbs amino acid metabolism in the fission yeast model of Batten disease

artículo científico publicado en 2010

Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1‐13C]pyruvate ⬇️

artículo científico publicado el 8 de marzo de 2011

Dietary inorganic nitrate: From villain to hero in metabolic disease?

artículo científico publicado en 2016

Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study

artículo científico publicado en 2014

Differential translocation of the fatty acid transporter, FAT/CD36, and the glucose transporter, GLUT4, coordinates changes in cardiac substrate metabolism during ischemia and reperfusion

artículo científico publicado en 2013

Does our gut microbiome predict cardiovascular risk? A review of the evidence from metabolomics

artículo científico publicado en 2015

Erratum to: COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

scholarly article published in Metabolomics

Erratum: Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance

artículo científico publicado en 2016

Fatty Acid and Glucose Sensors in Hepatic Lipid Metabolism: Implications in NAFLD.

artículo científico

Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes

Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation

artículo científico publicado en 2014

Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption. ⬇️

artículo científico publicado en 2018

Hyphenating size-exclusion chromatography with electrospray mass spectrometry; using on-line liquid-liquid extraction to study the lipid composition of lipoprotein particles

artículo científico publicado en 2015

Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse

artículo científico publicado en 2009

Inorganic Nitrate Mimics Exercise-Stimulated Muscular Fiber-Type Switching and Myokine and γ-Aminobutyric Acid Release ⬇️

artículo científico publicado en 2016

Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway ⬇️

artículo científico publicado en 2014

Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer-link to patient survival, hormone receptor status, and metabolic profiling

artículo científico publicado en 2011

Integration of metabolomics, lipidomics and clinical data using a machine learning method

artículo científico publicado en 2016

Leptin regulates peripheral lipid metabolism primarily through central effects on food intake

artículo científico publicado en 2008

Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease

artículo científico publicado en 2016

Lipocalin prostaglandin D synthase and PPARγ2 coordinate to regulate carbohydrate and lipid metabolism in vivo

artículo científico publicado en 2012

Liquid Extraction Surface Analysis Mass Spectrometry Method for Identifying the Presence and Severity of Nonalcoholic Fatty Liver Disease

artículo científico publicado en 2017

Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes

artículo científico publicado en 2015

MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data

artículo científico publicado en 2012

MetaboLights: An Open-Access Database Repository for Metabolomics Data

artículo científico publicado en 2016

MetaboLights: towards a new COSMOS of metabolomics data management

artículo científico publicado en 2012

Metabolic fingerprinting as a diagnostic tool.

artículo científico publicado en 2007

Metabolic phenotyping of a model of adipocyte differentiation

artículo científico publicado en 2009

Metabolite identification: are you sure? And how do your peers gauge your confidence?

article

Metabolomic analysis of akt1-mediated muscle hypertrophy in models of diet-induced obesity and age-related fat accumulation

artículo científico publicado en 2014

Metabolomic applications to neuroscience: more challenges than chances?

artículo científico publicado en 2007

Metabolomic investigation of CLN6 neuronal ceroid lipofuscinosis in affected South Hampshire sheep

artículo científico publicado en 2007

Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice

artículo científico publicado en 2010

Metabolomics as a functional genomic tool for understanding lipid dysfunction in diabetes, obesity and related disorders

artículo científico publicado en 2006

Metabolomics dataset of PPAR-pan treated rat liver ⬇️

artículo científico publicado en 2016

Metabolomics of human breast cancer: new approaches for tumor typing and biomarker discovery

artículo científico publicado en 2012

Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse

artículo científico publicado en 2009

Methods for performing lipidomics in white adipose tissue

artículo científico publicado en 2014

Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer

artículo científico publicado en 2016

NMR Spectroscopy of Tissues, 1 H MAS

NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations

Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism

artículo científico publicado en 2015

Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression

artículo científico publicado en 2011

Odd Chain Fatty Acids; New Insights of the Relationship Between the Gut Microbiota, Dietary Intake, Biosynthesis and Glucose Intolerance

artículo científico publicado en 2017

Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers

artículo científico publicado en 2013

PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling

artículo científico publicado en 2015

Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli.

artículo científico publicado en 2011

Proposed minimum reporting standards for chemical analysis

artículo científico publicado en 2007

Proposed reporting requirements for the description of NMR-based metabolomics experiments

article

Regulation of mitochondrial morphology and function by stearoylation of TFR1.

artículo científico publicado en 2015

Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue - a GC-TOFMS based metabolomics study

artículo científico publicado en 2012

Reply to Comment on “Deletion of btn1, an orthologue of CLN3, increases glycolysis and perturbs amino acid metabolism in the fission yeast model of Batten disease”

Response to Comment on Lee et al. Diabetes 2015;64:2836–2846. Comment on Roberts et al. Diabetes 2015;64:471–484

artículo científico publicado en 2016

So what have data standards ever done for us? The view from metabolomics

artículo científico publicado en 2010

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

artículo científico publicado en 2010

The Study of Mammalian Metabolism through NMR-based Metabolomics

article by Reza M. Salek et al published 2011 in Methods in Enzymology

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue

artículo científico publicado en 2011

The development and validation of a fast and robust dried blood spot based lipid profiling method to study infant metabolism

artículo científico publicado en 2014

The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice.

artículo científico publicado en 2011

The translation of lipid profiles to nutritional biomarkers in the study of infant metabolism ⬇️

artículo científico publicado en 2017

Toward interoperable bioscience data

artículo científico publicado en 2012

Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome

artículo científico publicado en 2013

Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis

artículo científico publicado en 2005

Whole blood transcriptomics and urinary metabolomics to define adaptive biochemical pathways of high-intensity exercise in 50-60 year old masters athletes

artículo científico publicado en 2014

massPix: an R package for annotation and interpretation of mass spectrometry imaging data for lipidomics

artículo científico publicado en 2017

nmrML: a community supported open data standard for the description, storage, and exchange of NMR data

artículo científico publicado en 2017

omega-3 oil intake during weight loss in obese women results in remodelling of plasma triglyceride and fatty acids

artículo científico publicado en 2009

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