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A targeting modality for destruction of RNA polymerase I that possesses anticancer activity.

artículo científico publicado en 2014

Characterization of novel cell lines derived from a MYC-driven murine model of lethal metastatic adenocarcinoma of the prostate

scientific article published on 30 May 2018

Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer

artículo científico publicado en 2015

Comprehensive urinary metabolomic characterization of a genetically induced mouse model of prostatic inflammation

scientific article published on 22 September 2018

Consequences of interleukin 1β-triggered chronic inflammation in the mouse prostate gland: Altered architecture associated with prolonged CD4+ infiltration mimics human proliferative inflammatory atrophy

scientific article published on 22 March 2019

Deep PIM kinase substrate profiling reveals new rational cotherapeutic strategies for acute myeloid leukemia

artículo científico publicado en 2024

ETS Related Gene mediated Androgen Receptor Aggregation and Endoplasmic Reticulum Stress in Prostate Cancer Development.

artículo científico publicado en 2017

Effective targeting of RNA polymerase I in treatment-resistant prostate cancer

scientific article published on 16 September 2019

Erratum: ETS Related Gene mediated Androgen Receptor Aggregation and Endoplasmic Reticulum Stress in Prostate Cancer Development.

artículo científico publicado en 2017

Functional and molecular features of the Id4+ germline stem cell population in mouse testes.

artículo científico publicado en 2014

Identification and validation of inhibitor-responsive kinase substrates using a new paradigm to measure kinase-specific protein phosphorylation index

artículo científico publicado en 2012

If this is true, what does it imply? How end-user antibody validation facilitates insights into biology and disease

scientific article published on 12 December 2018

MYC and Prostate Cancer

artículo científico publicado en 2010

MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells

artículo científico publicado en 2010

NKX3.1 as a marker of prostatic origin in metastatic tumors.

artículo científico publicado en 2010

Phosphorylation of NuMA by Aurora-A kinase in PC-3 prostate cancer cells affects proliferation, survival, and interphase NuMA localization.

artículo científico publicado en 2013

Proline-mediated proteasomal degradation of the prostate-specific tumor suppressor NKX3.1.

artículo científico publicado en 2012

Prostate cancer: New answers prompt new questions regarding cell of origin.

artículo científico publicado en 2010

Quantifying Kinase-Specific Phosphorylation Stoichiometry Using Stable Isotope Labeling In a Reverse In-Gel Kinase Assay.

artículo científico publicado en 2016

Quantitative proteomic analysis of a genetically induced prostate inflammation mouse model via custom 4-plex DiLeu isobaric labeling

scientific article published on 17 April 2019

Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy

artículo científico publicado en 2018

Regulating NKX3.1 stability and function: Post-translational modifications and structural determinants.

artículo científico publicado en 2016

Stabilization of the prostate-specific tumor suppressor NKX3.1 by the oncogenic protein kinase Pim-1 in prostate cancer cells.

artículo científico publicado en 2013