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A new myelin protein, TPPP/p25, reduced in demyelinated lesions is enriched in cerebrospinal fluid of multiple sclerosis

artículo científico publicado en 2011

Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study

artículo científico publicado en 2016

Brain-specific p25 protein binds to tubulin and microtubules and induces aberrant microtubule assemblies at substoichiometric concentrations

artículo científico publicado en 2002

Challenging drug target for Parkinson's disease: Pathological complex of the chameleon TPPP/p25 and alpha-synuclein proteins

artículo científico publicado en 2016

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).

artículo científico publicado en 2017

Dual life of TPPP/p25 evolved in physiological and pathological conditions.

artículo científico publicado en 2014

Further evidence for microtubule-independent dimerization of TPPP/p25.

scientific article published on 11 January 2017

Identification of motives mediating alternative functions of the neomorphic moonlighting TPPP/p25.

artículo científico publicado en 2014

Interaction of TPPP/p25 protein with glyceraldehyde-3-phosphate dehydrogenase and their co-localization in Lewy bodies

artículo científico publicado en 2006

Interactions between two regulatory proteins of microtubule dynamics, HDAC6, TPPP/p25, and the hub protein, DYNLL/LC8

artículo científico publicado en 2019

Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein

artículo científico publicado en 2011

Localization of the zinc binding tubulin polymerization promoting protein in the mice and human eye.

artículo científico publicado en 2017

Microtubule assembly-derived by dimerization of TPPP/p25. Evaluation of thermodynamic parameters for multiple equilibrium system from ITC data

artículo científico publicado en 2012

Modeling of sensing potency of cytoskeletal systems decorated with metabolic enzymes.

artículo científico publicado en 2014

Modulation Of Microtubule Acetylation By The Interplay Of TPPP/p25, SIRT2 And New Anticancer Agents With Anti-SIRT2 Potency.

artículo científico publicado en 2017

Moonlighting microtubule-associated proteins: regulatory functions by day and pathological functions at night

artículo científico publicado en 2013

Pharmacological targeting of α-synuclein and TPPP/p25 in Parkinson's disease: challenges and opportunities in a Nutshell

artículo científico publicado en 2019

Reappraisal of triosephosphate isomerase deficiency

artículo científico publicado en 2011

Role of the microtubule-associated TPPP/p25 in Parkinson's and related diseases and its therapeutic potential.

artículo científico publicado en 2017

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.

artículo científico publicado en 2015

TPPP/p25 promotes tubulin acetylation by inhibiting histone deacetylase 6

artículo científico publicado en 2010

TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation

artículo científico publicado en 2003

Targeting the interface of the pathological complex of α-synuclein and TPPP/p25.

artículo científico publicado en 2015

The Sherpa hypothesis: Phenotype-Preserving Disordered Proteins stabilize the phenotypes of neurons and oligodendrocytes

artículo científico publicado en 2023

Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease

artículo científico publicado en 2002

Tubulin Binding and Polymerization Promoting Properties of Tubulin Polymerization Promoting Proteins Are Evolutionarily Conserved.

artículo científico publicado en 2017

Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors.

artículo científico publicado en 2014

Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis

artículo científico publicado en 2010

Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions

artículo científico publicado en 2006

Zinc-induced structural changes of the disordered tppp/p25 inhibits its degradation by the proteasome

artículo científico publicado en 2014

Zn²+-induced rearrangement of the disordered TPPP/p25 affects its microtubule assembly and GTPase activity.

artículo científico publicado en 2011