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Achieving a cure for HIV infection: do we have reasons to be optimistic?

artículo científico

An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression

artículo científico publicado en 2015

Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef protein

artículo científico publicado en 2014

COUP-TF and Sp1 Interact and Cooperate in the Transcriptional Activation of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat in Human Microglial Cells

artículo científico publicado el 5 de diciembre de 1997

COUP-TF interacting protein 2 represses the initial phase of HIV-1 gene transcription in human microglial cells

artículo científico publicado en 2005

CTIP2 is a negative regulator of P-TEFb

artículo científico publicado en 2013

CTIP2, a multifunctional protein: cellular physiopathology and therapeutic implications

artículo científico publicado en 2014

Characterization of new RNA polymerase III and RNA polymerase II transcriptional promoters in the Bovine Leukemia Virus genome

artículo científico publicado en 2016

Chromatin disruption in the promoter of bovine leukemia virus during transcriptional activation

artículo científico publicado en 2011

Corrigendum: HIC1 controls cellular- and HIV-1- gene transcription via interactions with CTIP2 and HMGA1.

artículo científico publicado en 2017

DNA cytosine methylation in the Bovine Leukemia Virus promoter is associated with latency in a Lymphoma-derived B-cell line : potential involvement of direct inhibition of CREB/CREM/ATF binding

DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcr

artículo científico publicado en 2010

Genome-wide binding map of the HIV-1 Tat protein to the human genome

artículo científico publicado en 2011

HIC1 controls cellular- and HIV-1- gene transcription via interactions with CTIP2 and HMGA1.

artículo científico publicado en 2016

HIV-1 Vpr mediates the depletion of the cellular repressor CTIP2 to counteract viral gene silencing

scientific article published on 11 September 2019

HIV-1 regulation of latency in the monocyte-macrophage lineage and in CD4+ T lymphocytes

artículo científico publicado en 2009

HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters

artículo científico publicado en 2014

Heterogeneous HIV-1 Reactivation Patterns of Disulfiram and Combined Disulfiram+Romidepsin Treatments

scientific article published on 01 April 2019

Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients

artículo científico publicado en 2012

Human-Phosphate-Binding-Protein inhibits HIV-1 gene transcription and replication

artículo científico publicado en 2011

Identification and characterization of new Sp1 sites located in the R region of the Human T-lymphotropic virus 1 (HTLV-1) long terminal repeat.

artículo científico publicado en 2014

Identification of morphine-6-glucuronide in chromaffin cell secretory granules.

artículo científico publicado en 2006

Improving combination antiretroviral therapy by targeting HIV-1 gene transcription.

artículo científico publicado en 2016

In Trauma Patients, the Occurrence of Early-Onset Nosocomial Infections is Associated with Increased Plasma Concentrations of Chromogranin A.

artículo científico publicado en 2017

In vivo characterization of the BLV miRNA cluster

artículo científico publicado en 2015

In vivo characterization of the BLV miRNA cluster

LSD1 cooperates with CTIP2 to promote HIV-1 transcriptional silencing

artículo científico publicado en 2011

Microglial Cells: The Main HIV-1 Reservoir in the Brain

scientific article published on 24 October 2019

Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage

artículo científico publicado en 2010

Non-coding RNAs: novel players in chromatin-regulation during viral latency

artículo científico

On the way to find a cure: Purging latent HIV-1 reservoirs

artículo científico publicado en 2017

Proceedings of the Frontiers of Retrovirology Conference 2016.

artículo científico publicado en 2016

Protein Kinase C-Mediated Phosphorylation of BCL11B at Serine 2 Negatively Regulates Its Interaction with NuRD Complexes during CD4+ T-Cell Activation

artículo científico publicado en 2016

Pseudomonas DING proteins as human transcriptional regulators and HIV-1 antagonists

artículo científico publicado en 2013

Reactivation capacity by latency-reversing agents ex vivo correlates with the size of the HIV-1 reservoir

artículo científico publicado en 2016

Recruitment of Tat to heterochromatin protein HP1 via interaction with CTIP2 inhibits human immunodeficiency virus type 1 replication in microglial cells

artículo científico publicado en 2003

Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing

artículo científico publicado en 2007

Regulation of HIV-1 gene transcription: from lymphocytes to microglial cells

artículo científico publicado en 2003

Repression of Human T-lymphotropic virus type 1 Long Terminal Repeat sense transcription by Sp1 recruitment to novel Sp1 binding sites

scientific article published on 03 March 2017

Role of the cofactor CTIP2 (COUP-TF Interacting Protein 2) in the transcriptional repression of HTLV-1 (Human T-lymphotropic Virus 1)

Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1.

artículo científico publicado en 2015

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

artículo científico publicado en 2009

Targeting the Brain Reservoirs: Toward an HIV Cure

artículo científico publicado en 2016

Targeting the DNA-PK complex: Its rationale use in cancer and HIV-1 infection

artículo científico publicado en 2018

The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication

artículo científico publicado en 2011

The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for virus infectivity.

artículo científico publicado en 2009

The cellular cofactor CTIP2 is a negative p-TEFb regulator. Contribution to HIV-1 post-integration latency

article

The level of DING proteins is increased in HIV-infected patients: in vitro and in vivo studies

artículo científico publicado en 2012

The many lives of CTIP2: from AIDS to cancer and cardiac hypertrophy.

artículo científico

Toxoplasma gondii ROP16 kinase silences the cyclin B1 gene promoter by hijacking host cell UHRF1-dependent epigenetic pathways

scientific article published on 06 September 2019

Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line

artículo científico publicado en 2016

[DING proteins, their biochemical and structural properties, and their ability to inhibit HIV-1 replication].

artículo científico publicado en 2012

[Molecular basis of HIV-1 latency - Part II: HIV-1 reactivation and therapeutic implications]

scientific article published on 01 March 2010

[Molecular basis of HIV-1 latency - part I: physiology of HIV-1 latency]

artículo científico publicado en 2010