Lista de obras -

A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

artículo científico publicado en 2013

A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice

artículo científico publicado en 2010

Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease

scholarly article by Silke Nuber et al published 10 October 2018 in Neuron

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo ⬇️

artículo científico publicado en 2014

Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway

artículo científico publicado en 2012

Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein ⬇️

artículo científico publicado el 9 de enero de 2013

Caspase-1 clipping causes complications for α-synuclein

scientific article published on 22 August 2016

Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein

artículo científico publicado en 2009

Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α-synuclein

artículo científico publicado en 2015

Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD.

artículo científico publicado en 2014

Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models.

artículo científico publicado en 2006

First appraisal of brain pathology owing to A30P mutant alpha-synuclein

artículo científico publicado en 2010

Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice

artículo científico publicado en 2013

Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors

artículo científico publicado en 2014

Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells

artículo científico publicado en 2017

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

artículo científico publicado en 2015

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

artículo científico publicado en 2016

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.

artículo científico publicado en 2008

Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

artículo científico publicado en 2011

Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice

artículo científico publicado en 2013

Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice

artículo científico publicado en 2014

Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models

artículo científico publicado en 2014

Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease

artículo científico publicado en 2015

Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice

artículo científico publicado en 2010

rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration

artículo científico publicado en 2013

α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy

artículo científico publicado en 2014

Lista de obras de

A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice

Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo ⬇️

Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway

Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein ⬇️

Caspase-1 clipping causes complications for α-synuclein

Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein

Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α-synuclein

Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD.

Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models.

First appraisal of brain pathology owing to A30P mutant alpha-synuclein

Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice

Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors

Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.

Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice

Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice

Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models

Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease

Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice

rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration

α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy