Lista de obras -

A 'top-down' approach to the determination of control coefficients in metabolic control theory

artículo científico publicado en 1990

Activated human neutrophils rapidly break down nitric oxide

artículo científico publicado en 1997

Activated microglia cause reversible apoptosis of pheochromocytoma cells, inducing their cell death by phagocytosis

artículo científico publicado en 2015

Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration

artículo científico publicado en 2005

Amyloid β induces microglia to phagocytose neurons via activation of protein kinase Cs and NADPH oxidase

artículo científico publicado en 2016

Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory

artículo científico publicado en 1990

Anthocyanins block ischemia-induced apoptosis in the perfused heart and support mitochondrial respiration potentially by reducing cytosolic cytochrome c.

artículo científico publicado en 2012

Anti-CD47 antibodies induce phagocytosis of live, malignant B cells by macrophages via the Fc domain, resulting in cell death by phagoptosis

artículo científico publicado en 2017

Ca2+ stimulates both the respiratory and phosphorylation subsystems in rat heart mitochondria

artículo científico publicado en 1996

Calcium indirectly increases the control exerted by the adenine nucleotide translocator over 2-oxoglutarate oxidation in rat heart mitochondria.

artículo científico publicado en 1995

Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia

scientific journal article

Cell biology. NO says yes to mitochondria

artículo científico publicado en 2003

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

artículo científico publicado en 1997

Changes in permeability to protons and other cations at high proton motive force in rat liver mitochondria

artículo científico publicado en 1986

Control analysis applied to single enzymes: can an isolated enzyme have a unique rate-limiting step?

artículo científico publicado en 1993

Control and kinetic analysis of ischemia-damaged heart mitochondria: which parts of the oxidative phosphorylation system are affected by ischemia?

article

Control of oxidative phosphorylation, gluconeogenesis, ureagenesis and ATP turnover in isolated perfused rat liver analyzed by top-down metabolic control analysis

scientific article published on 01 May 1998

Control of respiration and ATP synthesis in mammalian mitochondria and cells

artículo científico publicado en 1992

Control of respiration and oxidative phosphorylation in isolated rat liver cells

artículo científico publicado en 1990

Cytochrome c and activation of caspases during myocardial ischaemia

artículo científico publicado en 1998

Cytochrome oxidase content of rat brain during development

artículo científico publicado en 1991

Deciphering microglial diversity in Alzheimer's disease

artículo científico publicado en 2017

Deoxyglucose prevents neurodegeneration in culture by eliminating microglia

artículo científico publicado en 2014

Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine

artículo científico publicado en 2009

Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression

artículo científico publicado en 2002

Diffusion control of protein phosphorylation in signal transduction pathways

artículo científico publicado en 2000

Eaten alive! Cell death by primary phagocytosis: 'phagoptosis'.

artículo científico publicado en 2012

Electrostatic coupling between membrane proteins

artículo científico publicado en 1990

Fibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture study

artículo científico publicado en 2006

Highly purified lipoteichoic acid induced pro-inflammatory signalling in primary culture of rat microglia through Toll-like receptor 2: selective potentiation of nitric oxide production by muramyl dipeptide

artículo científico publicado en 2006

How microglia kill neurons

artículo científico

In the eye of the storm: mitochondrial damage during heart and brain ischaemia

artículo científico

Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells

artículo científico publicado en 2013

Inflammatory neurodegeneration and mechanisms of microglial killing of neurons

artículo científico publicado en 2010

Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation

artículo científico publicado en 2005

Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria

artículo científico publicado en 2003

Inhibition of UDP/P2Y6 purinergic signaling prevents phagocytosis of viable neurons by activated microglia in vitro and in vivo

artículo científico publicado en 2014

Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death

scientific journal article

Inhibition of mitochondrial permeability transition prevents mitochondrial dysfunction, cytochrome c release and apoptosis induced by heart ischemia

artículo científico publicado en 2003

Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols

artículo científico publicado en 2004

Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species

artículo científico publicado en 2006

Introduction: Focus on mitochondria

artículo científico publicado en 2013

Kinetic analysis of changes in activity of heart mitochondrial oxidative phosphorylation system induced by ischemia

scientific article published on 01 October 1996

Lactadherin/MFG-E8 is essential for microglia-mediated neuronal loss and phagoptosis induced by amyloid β.

artículo científico publicado en 2013

Living too long: the current focus of medical research on increasing the quantity, rather than the quality, of life is damaging our health and harming the economy

artículo científico publicado en 2014

MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation.

artículo científico publicado en 2012

Mechanisms of inflammatory neurodegeneration: iNOS and NADPH oxidase

artículo científico publicado en 2007

Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase

artículo científico publicado en 2006

Microglial phagocytosis of live neurons

artículo científico

Mitochondria in apoptosis of ischemic heart

artículo científico publicado en 2003

Mitochondria mediate nitric oxide-induced cell death

scientific article published on 01 January 1999

Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state

artículo científico publicado en 2007

Molecular Control Analysis: Control within Proteins and Molecular Processes

article

Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

scientific article published on 01 December 1994

Near-infrared spectroscopy of the brain: relevance to cytochrome oxidase bioenergetics

artículo científico publicado en 1994

Neurodegeneration in models of Gram-positive bacterial infections of the central nervous system

artículo científico publicado en 2007

Neuroinflammation in Alzheimer's disease

artículo científico publicado en 2015

Neuronal death induced by nanomolar amyloid β is mediated by primary phagocytosis of neurons by microglia

artículo científico publicado en 2011

Neurophagy, the phagocytosis of live neurons and synapses by glia, contributes to brain development and disease

artículo científico publicado en 2017

Nitric oxide and calcium together inactivate mitochondrial complex I and induce cytochrome c release

artículo científico publicado en 2003

Nitric oxide and mitochondria

artículo científico publicado en 2007

Nitric oxide and mitochondrial respiration

artículo científico publicado en 1999

Nitric oxide and mitochondrial respiration in the heart

artículo científico publicado en 2007

Nitric oxide and neuronal death

scientific article published on 12 June 2010

Nitric oxide and oxygen metabolism

artículo científico publicado en 1997

Nitric oxide as a competitive inhibitor of oxygen consumption in the mitochondrial respiratory chain

artículo científico publicado en 2000

Nitric oxide causes release of glutamate from brain synaptosomes

artículo científico publicado en 1997

Nitric oxide donors, nitrosothiols and mitochondrial respiration inhibitors induce caspase activation by different mechanisms

artículo científico publicado en 2000

Nitric oxide from inducible nitric oxide synthase sensitizes the inflamed aorta to hypoxic damage via respiratory inhibition

artículo científico publicado en 2005

Nitric oxide from inflammatory-activated glia synergizes with hypoxia to induce neuronal death

artículo científico publicado en 2005

Nitric oxide from neuronal nitric oxide synthase sensitises neurons to hypoxia-induced death via competitive inhibition of cytochrome oxidase

artículo científico publicado en 2007

Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion

artículo científico publicado en 2003

Nitric oxide induces rapid, calcium-dependent release of vesicular glutamate and ATP from cultured rat astrocytes

artículo científico publicado en 2002

Nitric oxide inhibition of cytochrome oxidase and mitochondrial respiration: implications for inflammatory, neurodegenerative and ischaemic pathologies

artículo científico publicado el 1 de septiembre de 1997

Nitric oxide inhibition of mitochondrial respiration and its role in cell death

artículo científico publicado en 2002

Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration

scientific article published on 01 July 1995

Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release

artículo científico publicado en 2009

Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase ⬇️

artículo científico publicado el 7 de agosto de 1995

Nitric oxide stimulates PC12 cell proliferation via cGMP and inhibits at higher concentrations mainly via energy depletion

artículo científico publicado en 2005

Nitric oxide, cytochrome c and mitochondria

artículo científico publicado en 1999

Nitric oxide, hypoxia and brain inflammation

artículo científico publicado en 2004

Nitric oxide, mitochondria, and cell death

artículo científico publicado en 2001

Nitric oxide-dependent damage to neuronal mitochondria involves the NMDA receptor.

artículo científico publicado en 2002

Nitric oxide-induced cell death of cerebrocortical murine astrocytes is mediated through p53- and Bax-dependent pathways

artículo científico publicado en 2004

Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria

artículo científico publicado en 2000

On the mechanism by which vascular endothelial cells regulate their oxygen consumption

artículo científico publicado en 1999

Paradoxical control properties of enzymes within pathways: can activation cause an enzyme to have increased control?

artículo científico publicado en 1996

Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione.

artículo científico publicado en 1998

Phagocytosis executes delayed neuronal death after focal brain ischemia

artículo científico publicado en 2013

Phagoptosis - Cell Death By Phagocytosis - Plays Central Roles in Physiology, Host Defense and Pathology

artículo científico publicado en 2015

Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration

artículo científico publicado en 2012

Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling

artículo científico publicado en 2012

Production of peroxynitrite from nitric oxide, hydrogen peroxide and superoxide dismutase: pathological implications

artículo científico publicado en 1997

Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio

artículo científico publicado en 1988

Quantification of information transfer via cellular signal transduction pathways ⬇️

artículo científico publicado el 8 de septiembre de 1997

Quantification of the relative contribution of parallel pathways to signal transfer: application to cellular energy transduction

artículo científico publicado en 1998

Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide

artículo científico publicado en 1996

Rate control within the Na+/glucose cotransporter

artículo científico publicado en 1995

Rate limitation within a single enzyme is directly related to enzyme intermediate levels

artículo científico publicado en 1994

Regulation of apoptosis by the redox state of cytochrome c.

artículo científico publicado en 2008

Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase

artículo científico publicado en 2001

Release of cytochrome c from heart mitochondria is induced by high Ca2+ and peroxynitrite and is responsible for Ca(2+)-induced inhibition of substrate oxidation

artículo científico publicado en 1999

Release of mitochondrial cytochrome c and activation of cytosolic caspases induced by myocardial ischaemia

scientific article published on 01 September 2001

Reversal of nitric oxide-, peroxynitrite- and S-nitrosothiol-induced inhibition of mitochondrial respiration or complex I activity by light and thiols

artículo científico publicado en 2000

Reversible binding and inhibition of catalase by nitric oxide

artículo científico publicado en 1995

Reversible inhibition of cellular respiration by nitric oxide in vascular inflammation

artículo científico publicado en 2001

Rotenone induces neuronal death by microglial phagocytosis of neurons

artículo científico publicado en 2013

S-nitrosothiol inhibition of mitochondrial complex I causes a reversible increase in mitochondrial hydrogen peroxide production

artículo científico publicado en 2006

S-nitrosothiol-induced rapid cytochrome c release, caspase activation and mitochondrial permeability transition in perfused heart

artículo científico publicado en 2003

Spatial gradients of cellular phospho-proteins

artículo científico publicado en 1999

Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production

artículo científico publicado en 2002

Superoxide dismutase and hydrogen peroxide cause rapid nitric oxide breakdown, peroxynitrite production and subsequent cell death

artículo científico publicado en 1999

Tetramethylphenylenediamine protects the isolated heart against ischaemia-induced apoptosis and reperfusion-induced necrosis

artículo científico publicado en 2011

The NO donor DETA-NONOate reversibly activates an inward current in neurones and is not mediated by the released nitric oxide

artículo científico publicado en 2009

The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

artículo científico publicado en 2008

The interactions between nitric oxide and brain nerve terminals as studied by electron paramagnetic resonance

scientific article published on 01 July 1995

The principle of sufficiency and the evolution of control: using control analysis to understand the design principles of biological systems

artículo científico publicado en 2010

There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells

artículo científico publicado en 2011

Thermodynamic and steady-state-kinetic investigation of the effect of NN'-dicyclohexylcarbodi-imide on H+ translocation by the mitochondrial cytochrome bc1 complex

artículo científico publicado en 1985

Thermodynamic control of electron flux through mitochondrial cytochrome bc1 complex

artículo científico publicado en 1985

Thermodynamic limits to the stoichiometry of H+ pumping by mitochondrial cytochrome oxidase.

artículo científico publicado en 1985

Thyroid-hormone control of state-3 respiration in isolated rat liver mitochondria

artículo científico publicado en 1990

Total cell protein concentration as an evolutionary constraint on the metabolic control distribution in cells ⬇️

artículo científico publicado el 21 de noviembre de 1991

Transcellular regulation of cell respiration by nitric oxide generated by activated macrophages

artículo científico publicado en 1998

Tumour necrosis factor alpha-induced neuronal loss is mediated by microglial phagocytosis

artículo científico publicado en 2014

Why do protein kinase cascades have more than one level?

artículo científico publicado en 1997

Lista de obras de

A 'top-down' approach to the determination of control coefficients in metabolic control theory

Activated human neutrophils rapidly break down nitric oxide

Activated microglia cause reversible apoptosis of pheochromocytoma cells, inducing their cell death by phagocytosis

Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration

Amyloid β induces microglia to phagocytose neurons via activation of protein kinase Cs and NADPH oxidase

Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory

Anthocyanins block ischemia-induced apoptosis in the perfused heart and support mitochondrial respiration potentially by reducing cytosolic cytochrome c.

Anti-CD47 antibodies induce phagocytosis of live, malignant B cells by macrophages via the Fc domain, resulting in cell death by phagoptosis

Ca2+ stimulates both the respiratory and phosphorylation subsystems in rat heart mitochondria

Calcium indirectly increases the control exerted by the adenine nucleotide translocator over 2-oxoglutarate oxidation in rat heart mitochondria.

Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia

Cell biology. NO says yes to mitochondria

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

Changes in permeability to protons and other cations at high proton motive force in rat liver mitochondria

Control analysis applied to single enzymes: can an isolated enzyme have a unique rate-limiting step?

Control and kinetic analysis of ischemia-damaged heart mitochondria: which parts of the oxidative phosphorylation system are affected by ischemia?

Control of oxidative phosphorylation, gluconeogenesis, ureagenesis and ATP turnover in isolated perfused rat liver analyzed by top-down metabolic control analysis

Control of respiration and ATP synthesis in mammalian mitochondria and cells

Control of respiration and oxidative phosphorylation in isolated rat liver cells

Cytochrome c and activation of caspases during myocardial ischaemia

Cytochrome oxidase content of rat brain during development

Deciphering microglial diversity in Alzheimer's disease

Deoxyglucose prevents neurodegeneration in culture by eliminating microglia

Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine

Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression

Diffusion control of protein phosphorylation in signal transduction pathways

Eaten alive! Cell death by primary phagocytosis: 'phagoptosis'.

Electrostatic coupling between membrane proteins

Fibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture study

Highly purified lipoteichoic acid induced pro-inflammatory signalling in primary culture of rat microglia through Toll-like receptor 2: selective potentiation of nitric oxide production by muramyl dipeptide

How microglia kill neurons

In the eye of the storm: mitochondrial damage during heart and brain ischaemia

Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells

Inflammatory neurodegeneration and mechanisms of microglial killing of neurons

Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation

Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria

Inhibition of UDP/P2Y6 purinergic signaling prevents phagocytosis of viable neurons by activated microglia in vitro and in vivo

Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death

Inhibition of mitochondrial permeability transition prevents mitochondrial dysfunction, cytochrome c release and apoptosis induced by heart ischemia

Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols

Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species

Introduction: Focus on mitochondria

Kinetic analysis of changes in activity of heart mitochondrial oxidative phosphorylation system induced by ischemia

Lactadherin/MFG-E8 is essential for microglia-mediated neuronal loss and phagoptosis induced by amyloid β.

Living too long: the current focus of medical research on increasing the quantity, rather than the quality, of life is damaging our health and harming the economy

MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation.

Mechanisms of inflammatory neurodegeneration: iNOS and NADPH oxidase

Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase

Microglial phagocytosis of live neurons

Mitochondria in apoptosis of ischemic heart

Mitochondria mediate nitric oxide-induced cell death

Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state

Molecular Control Analysis: Control within Proteins and Molecular Processes

Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

Near-infrared spectroscopy of the brain: relevance to cytochrome oxidase bioenergetics

Neurodegeneration in models of Gram-positive bacterial infections of the central nervous system

Neuroinflammation in Alzheimer's disease

Neuronal death induced by nanomolar amyloid β is mediated by primary phagocytosis of neurons by microglia

Neurophagy, the phagocytosis of live neurons and synapses by glia, contributes to brain development and disease

Nitric oxide and calcium together inactivate mitochondrial complex I and induce cytochrome c release

Nitric oxide and mitochondria

Nitric oxide and mitochondrial respiration

Nitric oxide and mitochondrial respiration in the heart

Nitric oxide and neuronal death

Nitric oxide and oxygen metabolism

Nitric oxide as a competitive inhibitor of oxygen consumption in the mitochondrial respiratory chain

Nitric oxide causes release of glutamate from brain synaptosomes

Nitric oxide donors, nitrosothiols and mitochondrial respiration inhibitors induce caspase activation by different mechanisms

Nitric oxide from inducible nitric oxide synthase sensitizes the inflamed aorta to hypoxic damage via respiratory inhibition

Nitric oxide from inflammatory-activated glia synergizes with hypoxia to induce neuronal death

Nitric oxide from neuronal nitric oxide synthase sensitises neurons to hypoxia-induced death via competitive inhibition of cytochrome oxidase

Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion

Nitric oxide induces rapid, calcium-dependent release of vesicular glutamate and ATP from cultured rat astrocytes

Nitric oxide inhibition of cytochrome oxidase and mitochondrial respiration: implications for inflammatory, neurodegenerative and ischaemic pathologies

Nitric oxide inhibition of mitochondrial respiration and its role in cell death

Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration

Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release

Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase ⬇️

Nitric oxide stimulates PC12 cell proliferation via cGMP and inhibits at higher concentrations mainly via energy depletion