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A library approach for the discovery of customized yeast three-hybrid counter selections

artículo científico publicado en 2011

Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library

artículo científico publicado en 2017

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

scientific article published on 13 July 2016

Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations

scientific article published on 10 January 2019

Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR

artículo científico publicado en 2020

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.

artículo científico publicado en 2016

Detergent- and phospholipid-based reconstitution systems have differential effects on constitutive activity of G-protein-coupled receptors

artículo científico publicado en 2019

Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor.

artículo científico publicado en 2013

Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody

scientific article published on 10 January 2019

G protein–coupled receptor kinases (GRKs) orchestrate biased agonism at the β2-adrenergic receptor

article

Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor

artículo científico publicado en 2020

Rapid generation of potent antibodies by autonomous hypermutation in yeast

scientific article published on 11 November 2020

Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies.

artículo científico publicado en 2013

Reiterative Recombination for the in vivo assembly of libraries of multigene pathways.

artículo científico publicado en 2011

Small-Molecule Positive Allosteric Modulators of the β2-Adrenoceptor Isolated from DNA-Encoded Libraries

scientific article published on 16 May 2018

Synthetic nanobodies as angiotensin receptor blockers

artículo científico publicado en 2020

Transcriptional regulation improves the throughput of three-hybrid counter selections in Saccharomyces cerevisiae.

artículo científico publicado en 2013