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Lista de obras de Michael Howell

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice

scientific article published on 03 September 2019

A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest ⬇️

scientific article published on 01 April 2019

APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability

artículo científico publicado en 2017

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

artículo científico publicado en 2015

Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability

artículo científico publicado en 2017

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study

artículo científico publicado en 2021

Affordable luciferase reporter assay for cell-based high-throughput screening.

artículo científico publicado en 2012

Anomalous inhibition of c-Met by the kinesin inhibitor aurintricarboxylic acid.

artículo científico publicado en 2011

Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN study

artículo científico publicado en 2022

Binding of dynein intermediate chain 2 to paxillin controls focal adhesion dynamics and migration.

artículo científico publicado en 2012

Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability

artículo científico publicado en 2014

Chromosomal instability confers intrinsic multidrug resistance.

artículo científico publicado en 2011

Chromosomal instability determines taxane response

scholarly article

Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer.

artículo científico publicado en 2014

Cytoplasmic ATR Activation Promotes Vaccinia Virus Genome Replication

artículo científico publicado en 2017

Defining host-pathogen interactions employing an artificial intelligence workflow

artículo científico publicado en 2019

Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion

artículo científico publicado en 2014

Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.

artículo científico publicado en 2012

HTS-DB: an online resource to publish and query data from functional genomics high-throughput siRNA screening projects

artículo científico publicado en 2013

High-throughput screening approaches to identify regulators of mammalian autophagy.

artículo científico publicado en 2015

Identification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME Screen

artículo científico publicado en 2019

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.

artículo científico publicado en 2016

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

artículo científico publicado en 2016

MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2019

Manipulating signal delivery - plasma-membrane ERK activation in aPKC-dependent migration.

artículo científico publicado en 2010

Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance

artículo científico publicado en 2022

Multiomic Analysis of the UV-Induced DNA Damage Response ⬇️

artículo científico publicado en 2016

PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways.

artículo científico publicado en 2011

Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export.

artículo científico publicado en 2018

Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila.

artículo científico publicado en 2013

Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis

artículo científico publicado en 2020

Tales from an academic RNAi screening facility; FAQs.

artículo científico publicado en 2011

The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery

scientific article published on 01 November 2018

The centriolar satellite protein Cep131 is important for genome stability

artículo científico publicado en 2012

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma

scientific article published on 05 June 2018

The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17.

artículo científico publicado en 2015

USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer

artículo científico publicado en 2022

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene

artículo científico publicado en 2017

Validation and Invalidation of Chemical Probes for the Human N-myristoyltransferases

scientific article published on 18 April 2019

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