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A function of huntingtin in guanine nucleotide exchange on Rab11.

artículo científico publicado en 2008

A short-chain alpha-neurotoxin from Naja naja atra produces potent cholinergic-dependent analgesia

artículo científico publicado en 2006

An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

scientific journal article

Analgesic effects of receptin, a chemically modified cobratoxin from Thailand cobra venom

artículo científico publicado en 2006

Anti-Inflammatory and Immune Regulatory Actions of Naja naja atra Venom

artículo científico publicado en 2018

Antinociceptive and anti-inflammatory effects of orally administrated denatured naja naja atra venom on murine rheumatoid arthritis models

artículo científico publicado en 2013

Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells

artículo científico publicado en 2009

Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning

artículo científico publicado en 2010

Autophagy and its possible roles in nervous system diseases, damage and repair

artículo científico publicado en 2005

Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning

artículo científico publicado el 24 de febrero de 2012

Autophagy regulates the processing of amino terminal huntingtin fragments

artículo científico publicado el 21 de octubre de 2003

Bilobalide inhibits 6-OHDA-induced activation of NF-kappaB and loss of dopaminergic neurons in rat substantia nigra

artículo científico publicado en 2008

Blocking NF-κB nuclear translocation leads to p53-related autophagy activation and cell apoptosis

artículo científico publicado el 28 de enero de 2011

Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats.

artículo científico publicado en 2013

Cobratoxin inhibits pain-evoked discharge of neurons in thalamic parafascicular nucleus in rats: involvement of cholinergic and serotonergic systems

artículo científico publicado en 2009

Cobrotoxin extracted from Naja atra venom relieves arthritis symptoms through anti-inflammation and immunosuppression effects in rat arthritis model

artículo científico publicado en 2016

Cobrotoxin from Naja naja atra Venom Ameliorates Adriamycin Nephropathy in Rats

artículo científico publicado en 2015

Combination of NAD(+) and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress

artículo científico publicado en 2017

Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke

artículo científico publicado en 2017

Contributions of autophagic and apoptotic mechanisms to CrTX-induced death of K562 cells

artículo científico publicado en 2006

Corrigendum to "Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke" [Free Radic. Biol. Med. 104 (2017) 333-345].

artículo científico publicado en 2017

Crotoxin enhances the antitumor activity of gefinitib (Iressa) in SK-MES-1 human lung squamous carcinoma cells

artículo científico publicado en 2012

Current understanding on the pathogenesis of polyglutamine diseases

scientific article published on June 2010

DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway

DRAM1 regulates autophagy flux through lysosomes

artículo científico publicado en 2013

DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities

artículo científico publicado en 2009

Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment?

artículo científico publicado en 2013

Development of novel therapies for Huntington's disease: hope and challenge

artículo científico publicado en 2005

Down-regulation of Bcl-2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum.

artículo científico publicado en 2009

Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism

artículo científico publicado en 2007

Dysfunction of nucleus accumbens-1 activates cellular senescence and inhibits tumor cell proliferation and oncogenesis

artículo científico publicado en 2012

Effects of LY294002 on the invasiveness of human gastric cancer in vivo in nude mice

artículo científico publicado en 2009

Endogenous level of TIGAR in brain is associated with vulnerability of neurons to ischemic injury

artículo científico publicado en 2015

Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells

artículo científico publicado en 2015

Enhancement of neuroprotection and heat shock protein induction by combined prostaglandin A1 and lithium in rodent models of focal ischemia

artículo científico publicado en 2006

Erratum to "Ameliorating Adriamycin-Induced Chronic Kidney Disease in Rats by Orally Administrated Cardiotoxin from Naja naja atra Venom".

artículo científico publicado en 2015

G6PD plays a neuroprotective role in brain ischemia through promoting pentose phosphate pathway

artículo científico publicado en 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Huntingtin processing in pathogenesis of Huntington disease.

artículo científico publicado en 2004

Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes

artículo científico publicado en 2007

Inflammatory mechanism in ischemic neuronal injury.

artículo científico publicado en 2006

Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury

artículo científico publicado el 28 de julio de 2012

Inhibitory effect of crotoxin on the pain-evoked discharge of neurons in thalamic parafascicular nucleus in rats

artículo científico publicado en 2007

Ischemia/reperfusion-induced upregulation of TIGAR in brain is mediated by SP1 and modulated by ROS and hormones involved in glucose metabolism

artículo científico publicado en 2014

Lysosomal Proteolysis Is Associated With Exercise-Induced Improvement of Mitochondrial Quality Control in Aged Hippocampus

artículo científico publicado en 2017

Lysosomal enzyme cathepsin B is involved in kainic acid-induced excitotoxicity in rat striatum

artículo científico publicado en 2006

Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death

artículo científico publicado en 2008

Melatonin ameliorates hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator (TIGAR).

artículo científico

Microglia activation contributes to quinolinic acid-induced neuronal excitotoxicity through TNF-α.

artículo científico publicado en 2017

Mitochondrial dysfunction and Huntington disease.

artículo científico publicado en 2006

Modulation of A-type K+ channels by the short-chain cobrotoxin through the protein kinase C-delta isoform decreases membrane excitability in dorsal root ganglion neurons.

artículo científico publicado en 2013

Molecular mechanism and regulation of autophagy

artículo científico publicado en 2005

NF-kappaB contributes to 6-hydroxydopamine-induced apoptosis of nigral dopaminergic neurons through p53.

artículo científico publicado en 2007

Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress

artículo científico publicado en 2014

Neuronal autophagy in cerebral ischemia

artículo científico publicado en 2012

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

scientific journal article

Neuroprotective effects of prostaglandin A(1) in rat models of permanent focal cerebral ischemia are associated with nuclear factor-kappaB inhibition and peroxisome proliferator-activated receptor-gamma up-regulation

artículo científico publicado en 2008

Neuroprotective effects of prostaglandin A1 in animal models of focal ischemia

artículo científico publicado en 2005

Neurotoxin from Naja naja atra venom inhibits skin allograft rejection in rats.

artículo científico publicado en 2015

Nuclear factor-kappaB-dependent cyclin D1 induction and DNA replication associated with N-methyl-D-aspartate receptor-mediated apoptosis in rat striatum

artículo científico publicado en 2007

O-GlcNAcylation Reduces Ischemia-Reperfusion-Induced Brain Injury

artículo científico publicado en 2017

Olomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine

artículo científico publicado en 2009

Opiate and acetylcholine-independent analgesic actions of crotoxin isolated from crotalus durissus terrificus venom

artículo científico publicado en 2006

Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazole (DY-9836), a novel c

artículo científico publicado en 2008

Poloxamer 188 protects neurons against ischemia/reperfusion injury through preserving integrity of cell membranes and blood brain barrier

artículo científico publicado en 2013

Prostaglandin A1 inhibits increases in intracellular calcium concentration, TXA(2) production and platelet activation

artículo científico publicado en 2006

Quality control system of the endoplasmic reticulum and related diseases

artículo científico publicado en 2006

Reduced Nicotinamide Adenine Dinucleotide Phosphate, a Pentose Phosphate Pathway Product, Might Be a Novel Drug Candidate for Ischemic Stroke

artículo científico publicado en 2015

Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells

artículo científico publicado el 11 de marzo de 2011

Regulatory genes controlling neural stem cells differentiation into neurons

artículo científico publicado en 2006

Sestrin2 Protects Dopaminergic Cells against Rotenone Toxicity through AMPK-Dependent Autophagy Activation

artículo científico publicado en 2015

Suppression of Inflammation and Arthritis by Orally Administrated Cardiotoxin from Naja naja atra

artículo científico publicado en 2015

Suppression of complete Freund's adjuvant-induced adjuvant arthritis by cobratoxin

artículo científico publicado en 2009

Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity

artículo científico publicado en 2005

TIGAR has a dual role in cancer cell survival through regulating apoptosis and autophagy

artículo científico publicado en 2014

TIGAR inhibits ischemia/reperfusion-induced inflammatory response of astrocytes

artículo científico publicado en 2018

The Protective Effects of Cobra Venom from Naja naja atra on Acute and Chronic Nephropathy

artículo científico publicado en 2013

The Role of Chaperone-Mediated Autophagy in Huntingtin Degradation

artículo científico publicado el 11 de octubre de 2012

The pro-survival role of autophagy depends on Bcl-2 under nutrition stress conditions

artículo científico publicado en 2013

The role of post-translational modifications of huntingtin in the pathogenesis of Huntington's disease

artículo científico publicado en 2010

The roles of the proteasome pathway in signal transduction and neurodegenerative diseases

artículo científico publicado en 2008

Transcription factor EB is involved in autophagy-mediated chemoresistance to doxorubicin in human cancer cells

artículo científico publicado en 2017

Ursolic acid induces human hepatoma cell line SMMC-7721 apoptosis via p53-dependent pathway

artículo científico publicado el 1 de julio de 2010

Whole Blood PCR Amplification with Pfu DNA Polymerase and Its Application in Single-Nucleotide Polymorphism Analysis.

artículo científico publicado en 2015

p38(MAPK)/p53-Mediated Bax induction contributes to neurons degeneration in rotenone-induced cellular and rat models of Parkinson's disease

artículo científico publicado en 2013

p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum

artículo científico publicado en 2009

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016