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ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange

artículo científico publicado en 2014

Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health.

scientific article published on 27 February 2017

Adipose tissue mitochondrial capacity associates with long-term weight loss success

artículo científico publicado en 2017

Animal disease models generated by genetic engineering of polyamine metabolism.

artículo científico publicado en 2005

Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults

artículo científico publicado en 2010

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

artículo científico publicado en 2007

Expression of urokinase-type plasminogen activator receptor is increased during epileptogenesis in the rat hippocampus.

artículo científico publicado en 2009

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

artículo científico publicado en 2017

Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions

scientific article published on 12 September 2019

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice.

artículo científico publicado en 2014

Mice with targeted disruption of spermidine/spermine N-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging

artículo científico publicado en 2006

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

artículo científico publicado en 2012

NAD+ repletion produces no therapeutic effect in mice with respiratory chain complex III deficiency and chronic energy deprivation

artículo científico publicado en 2018

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

artículo científico publicado en 2014

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice

article

Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins.

artículo científico publicado en 2015

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle

artículo científico publicado en 2014

Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis.

artículo científico publicado en 2014

Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.

artículo científico publicado en 2009

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

artículo científico publicado en 2012

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

artículo científico publicado en 2019

Transgenic rodents with altered SSAT expression as models of pancreatitis and altered glucose and lipid metabolism.

artículo científico publicado en 2011

Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue.

artículo científico publicado en 2016