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(6-bromo-1,4-dimethyl-9H-carbazol-3-yl-methylene)-hydrazine (carbhydraz) acts as a GPER agonist in breast cancer cells.

artículo científico publicado en 2015

A Bodipy as a luminescent probe for detection of the G protein estrogen receptor (GPER)

artículo científico publicado en 2015

A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models

artículo científico publicado en 2015

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

artículo científico publicado en 2018

Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts.

artículo científico publicado en 2012

Copper activates HIF-1α/GPER/VEGF signalling in cancer cells

artículo científico publicado en 2015

Corrigendum to "Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme"

scientific article published on 09 September 2020

Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs)

artículo científico publicado en 2015

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells

artículo científico publicado en 2019

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression

scientific article published on 07 March 2019

GPER mediates activation of HIF1α/VEGF signaling by estrogens

artículo científico publicado en 2014

GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts.

artículo científico publicado en 2016

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)

artículo científico publicado en 2013

Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts

artículo científico publicado en 2015

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells.

artículo científico publicado en 2012

Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands.

artículo científico publicado en 2015

Niacin activates the G protein estrogen receptor (GPER)-mediated signalling.

artículo científico publicado en 2014

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells

artículo científico publicado en 2013

Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme

scientific article published on 22 July 2019

SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer.

artículo científico publicado en 2015

Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells.

artículo científico publicado en 2016

The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives

artículo científico publicado en 2020

miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.

artículo científico publicado en 2018

miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs)

artículo científico publicado en 2018