Lista de obras -

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally

artículo científico publicado en 2017

8-Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual-Stage Antiplasmodial Activity

artículo científico publicado en 2019

A Duffy binding-like domain is involved in the NKp30-mediated recognition of Plasmodium falciparum-parasitized erythrocytes by natural killer cells

artículo científico publicado en 2007

AQ-13 - an investigational antimalarial drug

scientific article published on 05 January 2019

Antimalarial activity of the myxobacterial macrolide chlorotonil a. ⬇️

artículo científico publicado en 2014

Antimalarial compounds in Phase II clinical development.

artículo científico publicado en 2015

Bats are rare reservoirs of Staphylococcus aureus complex in Gabon.

artículo científico publicado en 2016

Behavioural and clinical predictors for Loiasis.

artículo científico publicado en 2018

Binding modes of reverse fosmidomycin analogs toward the antimalarial target IspC

artículo científico publicado en 2014

Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds

artículo científico publicado en 2014

Causes of fever in Gabonese children: a cross-sectional hospital-based study

artículo científico publicado en 2020

Characterization of Plasmodium infections among inhabitants of rural areas in Gabon

scientific article published on 05 July 2019

Clinical utility of tafenoquine in the prevention of relapse of malaria: a review on the mode of action and emerging trial data

article

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

scientific article published on 11 July 2019

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection

artículo científico publicado en 2017

Demography, maternal health and the epidemiology of malaria and other major infectious diseases in the rural department Tsamba-Magotsi, Ngounie Province, in central African Gabon

artículo científico publicado en 2017

Design and Synthesis of Novel Anti-Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit.

artículo científico publicado en 2017

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

artículo científico publicado en 2015

Effect of fluorescent dyes on in vitro-differentiated, late-stage Plasmodium falciparum gametocytes

artículo científico publicado en 2014

Essential and nonessential metal effects on extracellular Leishmania amazonensis in vitro

artículo científico publicado en 2019

Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: a phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study

artículo científico publicado en 2015

Harmicines - harmine and cinnamic acid hybrids as novel antiplasmodial hits

scientific article published on 29 November 2019

Histone deacetylase inhibitors with high in vitro activities against Plasmodium falciparum isolates collected from Gabonese children and adults

artículo científico publicado en 2019

Immune response to SARS-CoV-2 variants of concern in vaccinated individuals

artículo científico publicado en 2021

Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

artículo científico publicado en 2017

In vitro activity of eravacycline, a novel synthetic halogenated tetracycline, against the malaria parasite Plasmodium falciparum

scientific article published on 07 December 2020

In vitro activity of fluorescent dyes against asexual blood stages of Plasmodium falciparum.

artículo científico publicado en 2012

In vitro activity of mirincamycin (U24729A) against Plasmodium falciparum isolates from Gabon

artículo científico publicado en 2009

In vitro activity of new artemisinin derivatives against Plasmodium falciparum clinical isolates from Gabon

artículo científico publicado en 2011

In vitro activity of tigecycline in Plasmodium falciparum culture-adapted strains and clinical isolates from Gabon

artículo científico publicado en 2010

In vivo anti-malarial effect of the beta-amino alcohol 1t on Plasmodium berghei.

artículo científico publicado en 2009

Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

artículo científico publicado en 2011

IspC as target for antiinfective drug discovery: synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters

artículo científico publicado en 2013

Ivermectin Impairs the Development of Sexual and Asexual Stages of Plasmodium falciparum In Vitro

scientific article published on 25 July 2019

Lactate as a novel quantitative measure of viability in Schistosoma mansoni drug sensitivity assays

artículo científico publicado en 2014

Life-span of in vitro differentiated Plasmodium falciparum gametocytes

artículo científico

Longitudinal monitoring of laboratory markers characterizes hospitalized and ambulatory COVID-19 patients

artículo científico publicado en 2021

Molecular epidemiology of Mansonella species in Gabon

artículo científico publicado en 2020

Monitoring the threatened utility of malaria rapid diagnostic tests by novel high-throughput detection of Plasmodium falciparum hrp2 and hrp3 deletions: A cross-sectional, diagnostic accuracy study

artículo científico publicado en 2019

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

artículo científico publicado en 2016

Multicomponent Synthesis and Binding Mode of Imidazo[1,2- a]pyridine-Capped Selective HDAC6 Inhibitors

scientific article published on 23 May 2018

Non-Invasive Antibody Assessment in Saliva to Determine SARS-CoV-2 Exposure in Young Children

artículo científico publicado en 2021

Novel approaches in antimalarial drug discovery

artículo científico

Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity

scientific article published on 22 July 2019

Nycteria and Polychromophilus parasite infections of bats in Central Gabon

artículo científico publicado en 2018

One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites

scientific article published on 07 September 2018

Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Mala

artículo científico publicado en 2017

Prevalence of SARS-CoV-2 Infection in Children by Antibody Detection in Saliva: Protocol for a Prospective Longitudinal Study (Coro-Buddy)

artículo científico publicado en 2021

Primaquine and Chloroquine Fumardiamides as Promising Antiplasmodial Agents

scientific article published on 01 August 2019

Primaquine homodimers as potential antiplasmodial and anticancer agents

scientific article published on 10 August 2019

Prodrugs of reverse fosmidomycin analogues

artículo científico publicado en 2015

Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance.

artículo científico publicado en 2016

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

artículo científico publicado en 2017

Regional Variation of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacterales, Fluoroquinolone-Resistant Salmonella enterica and Methicillin-Resistant Staphylococcus aureus Among Febrile Patients in Sub-Saharan Africa

artículo científico publicado en 2020

SAHAquines, Novel Hybrids Based on SAHA and Primaquine Motifs, as Potential Cytostatic and Antiplasmodial Agents

artículo científico publicado en 2018

SARS-CoV-2 Antibodies Are Persisting in Saliva for More Than 15 Months After Infection and Become Strongly Boosted After Vaccination

artículo científico publicado en 2021

Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients

artículo científico publicado en 2017

Species and genotype diversity of Plasmodium in malaria patients from Gabon analysed by next generation sequencing.

artículo científico publicado en 2017

Sporozoite Route of Infection Influences In Vitro var Gene Transcription of Plasmodium falciparum Parasites From Controlled Human Infections.

artículo científico publicado en 2016

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

artículo científico publicado en 2017

Structure-Activity and Structure-Toxicity Relationships of Peptoid-Based Histone Deacetylase Inhibitors with Dual-Stage Antiplasmodial Activity

artículo científico publicado en 2019

Synthesis and antiplasmodial evaluation of novel mefloquine-based fumardiamides

scientific article published on 01 June 2019

Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells.

artículo científico publicado en 2014

Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum

scientific article published on 06 June 2019

Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.

artículo científico publicado en 2014

The preclinical discovery and development of rectal artesunate for the treatment of malaria in young children; review of evidence

scientific article published on 14 September 2020

Unbiased metagenomic next-generation sequencing of blood from hospitalized febrile children in Gabon

artículo científico publicado en 2020

α-Substituted β-oxa isosteres of fosmidomycin: synthesis and biological evaluation.

artículo científico publicado en 2012

Lista de obras de

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally

8-Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual-Stage Antiplasmodial Activity

A Duffy binding-like domain is involved in the NKp30-mediated recognition of Plasmodium falciparum-parasitized erythrocytes by natural killer cells

AQ-13 - an investigational antimalarial drug

Antimalarial activity of the myxobacterial macrolide chlorotonil a. ⬇️

Antimalarial compounds in Phase II clinical development.

Bats are rare reservoirs of Staphylococcus aureus complex in Gabon.

Behavioural and clinical predictors for Loiasis.

Binding modes of reverse fosmidomycin analogs toward the antimalarial target IspC

Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds

Causes of fever in Gabonese children: a cross-sectional hospital-based study

Characterization of Plasmodium infections among inhabitants of rural areas in Gabon

Clinical utility of tafenoquine in the prevention of relapse of malaria: a review on the mode of action and emerging trial data

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection

Demography, maternal health and the epidemiology of malaria and other major infectious diseases in the rural department Tsamba-Magotsi, Ngounie Province, in central African Gabon

Design and Synthesis of Novel Anti-Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit.

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

Effect of fluorescent dyes on in vitro-differentiated, late-stage Plasmodium falciparum gametocytes

Essential and nonessential metal effects on extracellular Leishmania amazonensis in vitro

Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: a phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study

Harmicines - harmine and cinnamic acid hybrids as novel antiplasmodial hits

Histone deacetylase inhibitors with high in vitro activities against Plasmodium falciparum isolates collected from Gabonese children and adults

Immune response to SARS-CoV-2 variants of concern in vaccinated individuals

Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

In vitro activity of eravacycline, a novel synthetic halogenated tetracycline, against the malaria parasite Plasmodium falciparum

In vitro activity of fluorescent dyes against asexual blood stages of Plasmodium falciparum.

In vitro activity of mirincamycin (U24729A) against Plasmodium falciparum isolates from Gabon

In vitro activity of new artemisinin derivatives against Plasmodium falciparum clinical isolates from Gabon

In vitro activity of tigecycline in Plasmodium falciparum culture-adapted strains and clinical isolates from Gabon

In vivo anti-malarial effect of the beta-amino alcohol 1t on Plasmodium berghei.

Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

IspC as target for antiinfective drug discovery: synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters

Ivermectin Impairs the Development of Sexual and Asexual Stages of Plasmodium falciparum In Vitro

Lactate as a novel quantitative measure of viability in Schistosoma mansoni drug sensitivity assays

Life-span of in vitro differentiated Plasmodium falciparum gametocytes

Longitudinal monitoring of laboratory markers characterizes hospitalized and ambulatory COVID-19 patients

Molecular epidemiology of Mansonella species in Gabon

Monitoring the threatened utility of malaria rapid diagnostic tests by novel high-throughput detection of Plasmodium falciparum hrp2 and hrp3 deletions: A cross-sectional, diagnostic accuracy study

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

Multicomponent Synthesis and Binding Mode of Imidazo[1,2- a]pyridine-Capped Selective HDAC6 Inhibitors

Non-Invasive Antibody Assessment in Saliva to Determine SARS-CoV-2 Exposure in Young Children

Novel approaches in antimalarial drug discovery

Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity

Nycteria and Polychromophilus parasite infections of bats in Central Gabon

One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites

Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Mala

Prevalence of SARS-CoV-2 Infection in Children by Antibody Detection in Saliva: Protocol for a Prospective Longitudinal Study (Coro-Buddy)

Primaquine and Chloroquine Fumardiamides as Promising Antiplasmodial Agents

Primaquine homodimers as potential antiplasmodial and anticancer agents

Prodrugs of reverse fosmidomycin analogues

Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance.

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

Regional Variation of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacterales, Fluoroquinolone-Resistant Salmonella enterica and Methicillin-Resistant Staphylococcus aureus Among Febrile Patients in Sub-Saharan Africa

SAHAquines, Novel Hybrids Based on SAHA and Primaquine Motifs, as Potential Cytostatic and Antiplasmodial Agents

SARS-CoV-2 Antibodies Are Persisting in Saliva for More Than 15 Months After Infection and Become Strongly Boosted After Vaccination

Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients

Species and genotype diversity of Plasmodium in malaria patients from Gabon analysed by next generation sequencing.

Sporozoite Route of Infection Influences In Vitro var Gene Transcription of Plasmodium falciparum Parasites From Controlled Human Infections.

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

Structure-Activity and Structure-Toxicity Relationships of Peptoid-Based Histone Deacetylase Inhibitors with Dual-Stage Antiplasmodial Activity

Synthesis and antiplasmodial evaluation of novel mefloquine-based fumardiamides

Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells.

Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum

Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.

The preclinical discovery and development of rectal artesunate for the treatment of malaria in young children; review of evidence

Unbiased metagenomic next-generation sequencing of blood from hospitalized febrile children in Gabon

α-Substituted β-oxa isosteres of fosmidomycin: synthesis and biological evaluation.