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Aspalathin Protects Insulin-Producing β Cells against Glucotoxicity and Oxidative Stress-Induced Cell Death

artículo científico publicado en 2020

Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations.

artículo científico publicado en 2009

Evidence against a role for NLRP3-driven islet inflammation in db/db mice.

artículo científico publicado en 2018

Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes

artículo científico publicado en 2012

Glucose regulation of islet stress responses and beta-cell failure in type 2 diabetes.

artículo científico publicado en 2009

Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.

artículo científico publicado en 2016

Inhibition of Y1 receptor signaling improves islet transplant outcome.

artículo científico publicado en 2017

Inhibitor of differentiation proteins protect against oxidative stress by regulating the antioxidant-mitochondrial response in mouse beta cells

artículo científico publicado en 2015

Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions

artículo científico publicado en 2017

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans

artículo científico publicado en 2019

NADPH oxidase-2 does not contribute to β-cell glucotoxicity in cultured pancreatic islets from C57BL/6J mice

artículo científico publicado en 2016

NPY signalling in early osteoblasts controls glucose homeostasis.

artículo científico publicado en 2015

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia

artículo científico publicado en 2015

Pancreatic PYY Is Critical in the Control of Insulin Secretion and Glucose Homeostasis in Female Mice.

artículo científico publicado en 2015

Phlda3 regulates beta cell survival during stress

scientific article published on 06 September 2019

The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.

artículo científico

Y1 receptor deficiency in β-cells leads to increased adiposity and impaired glucose metabolism

artículo científico publicado en 2018