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Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia

scientific article published on 04 December 2018

BCL2 inhibition in double hit lymphoma.

artículo científico publicado en 2015

BH3 mimetic therapy: an emerging and promising approach to treating chronic lymphocytic leukemia.

artículo científico publicado en 2013

Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199.

artículo científico publicado en 2014

Charcot-Leyden crystals

scientific article published on 01 November 2010

Clinicopathological features and outcomes of progression of CLL on the BCL2 inhibitor venetoclax.

artículo científico publicado en 2017

Current challenges and novel treatment strategies in double hit lymphomas

artículo científico publicado en 2016

Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma

scientific article published on 19 November 2018

Persistent complement-dependent anti-AnWj in a lymphoproliferative disorder: a case study and review.

artículo científico publicado en 2011

Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations

scientific article published on 03 June 2019

Targeting BCL2 for the treatment of lymphoid malignancies

artículo científico publicado en 2014

The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism.

artículo científico publicado en 2016

Transformed Lymphoma.

artículo científico publicado en 2016

Venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukaemia: a phase 1b study

artículo científico publicado en 2017

Venous thromboembolism management practices and knowledge of guidelines: a survey of Australian haematologists and respiratory physicians

artículo científico publicado en 2017

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