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Lista de obras de Debora Soncini

APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells

artículo científico publicado en 2015

CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells ⬇️

artículo científico publicado el 23 de julio de 2013

Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents.

artículo científico publicado en 2017

Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status.

artículo científico publicado en 2016

Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments: concordance with experimental results.

artículo científico publicado en 2010

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition

artículo científico publicado en 2015

Exploiting tumor vulnerabilities: NAD(+)-depleting agents combined with anti-tumor drugs as innovative strategy to treat hematological malignancies

artículo científico publicado en 2016

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.

artículo científico publicado en 2015

Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression

artículo científico publicado en 2010

Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma

scientific article published on 19 August 2019

Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors as therapeutics: rationales, controversies, clinical experience.

artículo científico publicado en 2013

Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity

artículo científico publicado en 2014

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

artículo científico publicado en 2017

Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors

artículo científico publicado en 2016

Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer.

artículo científico

The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses ⬇️

artículo científico publicado el 18 de octubre de 2012

Treatment with Angiotensin-(1–7) reduces inflammation in carotid atherosclerotic plaques

artículo científico publicado en 2014

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