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Competing aggregation pathways for monoclonal antibodies

artículo científico publicado en 2014

Dataset of the binding kinetic rate constants of anti-PCSK9 antibodies obtained using the Biacore T100, ProteOn XPR36, Octet RED384, and IBIS MX96 biosensor platforms

artículo científico publicado en 2016

Design and characterization of Zweimab and Doppelmab, high affinity dual antagonistic anti-TSLP/IL13 bispecific antibodies

scientific article published on 17 August 2018

Efficient Qualitative and Quantitative Determination of Antigen-induced Immune Responses.

artículo científico publicado en 2016

Fully human antibodies against the Protease-Activated Receptor-2 (PAR-2) with anti-inflammatory activity.

artículo científico publicado en 2011

Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies.

artículo científico publicado en 2017

IgG Charge: Practical and Biological Implications

artículo científico publicado en 2019

IgG cooperativity - Is there allostery? Implications for antibody functions and therapeutic antibody development.

artículo científico publicado en 2017

Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn.

artículo científico publicado en 2017

Non-neutralizing antibodies increase endogenous circulating Ang1 levels

artículo científico publicado en 2018

Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA expression data (FANTOM5)

scientific article published on 04 June 2019

Selective tumor cell apoptosis and tumor regression in CDH17-positive colorectal cancer models using BI 905711, a novel liver-sparing TRAILR2 agonist

scientific article published on 09 October 2020

VHH antibody targeting the chemokine receptor CX3CR1 inhibits progression of atherosclerosis

artículo científico publicado en 2020

Weak protein interactions and pH- and temperature-dependent aggregation of human Fc1.

artículo científico publicado en 2015

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