Lista de obras -

A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells.

artículo científico publicado en 2017

A Stro-1(+) human universal stromal feeder layer to expand/maintain human bone marrow hematopoietic stem/progenitor cells in a serum-free culture system.

artículo científico publicado en 2006

A human stromal-based serum-free culture system supports the ex vivo expansion/maintenance of bone marrow and cord blood hematopoietic stem/progenitor cells

artículo científico publicado en 2005

A novel method for human hematopoietic stem/progenitor cell isolation from umbilical cord blood based on immunoaffinity aqueous two-phase partitioning

artículo científico publicado en 2011

A xeno-free microcarrier-based stirred culture system for the scalable expansion of human mesenchymal stem/stromal cells isolated from bone marrow and adipose tissue.

artículo científico publicado en 2015

A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells

artículo científico publicado en 2014

Acellular Urethra Bioscaffold: Decellularization of Whole Urethras for Tissue Engineering Applications

artículo científico publicado en 2017

Addressing the Manufacturing Challenges of Cell-Based Therapies

artículo científico publicado en 2020

An appraisal of human mitochondrial DNA instability: new insights into the role of non-canonical DNA structures and sequence motifs.

artículo científico publicado en 2013

Biomimetic matrices for rapidly forming mineralized bone tissue based on stem cell-mediated osteogenesis

artículo científico publicado en 2018

Bioreactor design for clinical-grade expansion of stem cells.

artículo científico publicado en 2013

Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin sulfate supplementation

artículo científico publicado en 2020

Clinical-Grade Manufacturing of Therapeutic Human Mesenchymal Stem/Stromal Cells in Microcarrier-Based Culture Systems.

artículo científico publicado en 2016

Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering

scientific article published on 30 January 2019

Concise review: Genomic instability in human stem cells: current status and future challenges.

artículo científico publicado en 2014

Cultured cell-derived extracellular matrices to enhance the osteogenic differentiation and angiogenic properties of human mesenchymal stem/stromal cells

artículo científico publicado en 2019

Developing a co-culture system for effective megakaryo/thrombopoiesis from umbilical cord blood hematopoietic stem/progenitor cells

artículo científico publicado en 2015

Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics

artículo científico publicado en 2009

Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia.

artículo científico publicado en 2010

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage

artículo científico publicado en 2014

Dynamic cell-cell interactions between cord blood haematopoietic progenitors and the cellular niche are essential for the expansion of CD34+, CD34+CD38- and early lymphoid CD7+ cells.

artículo científico publicado en 2010

Engineering of Human Mesenchymal Stem/Stromal Cells with Vascular Endothelial Growth Factor-Encoding Minicircles for Angiogenic Ex Vivo Gene Therapy

scientific article published on 13 November 2018

Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells

artículo científico publicado en 2014

Ex vivo expansion of cord blood haematopoietic stem/progenitor cells under physiological oxygen tensions: clear-cut effects on cell proliferation, differentiation and metabolism.

artículo científico publicado en 2013

Ex vivo expansion of human mesenchymal stem cells: a more effective cell proliferation kinetics and metabolism under hypoxia.

artículo científico publicado en 2010

Extracellular matrix microarrays to study inductive signaling for endoderm specification

artículo científico publicado en 2016

Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly(ɛ-Caprolactone) Scaffolds

scientific article published on 21 October 2019

Gelatin porous scaffolds fabricated using a modified gas foaming technique: characterisation and cytotoxicity assessment.

artículo científico publicado en 2014

Gene delivery to human bone marrow mesenchymal stem cells by microporation.

artículo científico publicado en 2010

Hematopoietic Niche - Exploring Biomimetic Cues to Improve the Functionality of Hematopoietic Stem/Progenitor Cells

artículo científico publicado en 2017

Human mesenchymal stem cell expression program upon extended ex-vivo cultivation, as revealed by 2-DE-based quantitative proteomics.

artículo científico publicado en 2012

Human mesenchymal stem cells from the umbilical cord matrix: successful isolation and ex vivo expansion using serum-/xeno-free culture media.

artículo científico publicado en 2013

Impact of hypoxia and long-term cultivation on the genomic stability and mitochondrial performance of ex vivo expanded human stem/stromal cells

artículo científico publicado en 2012

In vitro assessment of three dimensional dense chitosan-based structures to be used as bioabsorbable implants.

artículo científico publicado en 2014

Initial CD34+ cell-enrichment of cord blood determines hematopoietic stem/progenitor cell yield upon ex vivo expansion.

artículo científico publicado en 2011

Integrated culture platform based on a human platelet lysate supplement for the isolation and scalable manufacturing of umbilical cord matrix-derived mesenchymal stem/stromal cells.

artículo científico publicado en 2016

Intracoronary Delivery of Human Mesenchymal/Stromal Stem Cells: Insights from Coronary Microcirculation Invasive Assessment in a Swine Model

artículo científico publicado en 2015

Kinetic and metabolic analysis of mouse embryonic stem cell expansion under serum-free conditions.

artículo científico publicado en 2009

Large-scale expansion of mouse embryonic stem cells on microcarriers.

artículo científico publicado en 2011

Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells

artículo científico publicado en 2020

Magnetoresistive chip cytometer.

artículo científico publicado en 2011

Maximizing the ex vivo expansion of human mesenchymal stem cells using a microcarrier-based stirred culture system

article

Mesenchymal stem cells from umbilical cord matrix, adipose tissue and bone marrow exhibit different capability to suppress peripheral blood B, natural killer and T cells.

artículo científico publicado en 2013

Microcarrier expansion of mouse embryonic stem cell-derived neural stem cells in stirred bioreactors.

artículo científico publicado en 2011

Mobile-Phase Modulators as Salt Tolerance Enhancers in Phenylboronate Chromatography: Thermodynamic Evaluation of the Mechanisms Underlying the Adsorption of Monoclonal Antibodies

artículo científico publicado en 2019

Modulation of the in vitro angiogenic potential of human mesenchymal stromal cells from different tissue sources

artículo científico publicado en 2020

Monitoring the ex-vivo expansion of human mesenchymal stem/stromal cells in xeno-free microcarrier-based reactor systems by MIR spectroscopy

artículo científico publicado en 2015

Oxazoline-based antimicrobial oligomers: synthesis by CROP using supercritical CO2.

artículo científico publicado en 2011

Polyhydroxyalkanoates: waste glycerol upgrade into electrospun fibrous scaffolds for stem cells culture

artículo científico publicado en 2014

Proliferation extent of CD34+ cells as a key parameter to maximize megakaryocytic differentiation of umbilical cord blood-derived hematopoietic stem/progenitor cells in a two-stage culture protocol

artículo científico publicado en 2014

Scalable ex vivo expansion of human mesenchymal stem/stromal cells in microcarrier-based stirred culture systems.

artículo científico publicado en 2015

Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells.

artículo científico publicado en 2016

Scale-up of mouse embryonic stem cell expansion in stirred bioreactors.

artículo científico publicado en 2011

Scaling up the ex vivo expansion of human circulating CD34(+)progenitor cells with upregulation of angiogenic and anti-inflammatory potential.

artículo científico publicado en 2015

Separation technologies for stem cell bioprocessing.

artículo científico

Stem Cell Bioprocessing and Manufacturing

artículo científico publicado en 2020

Stem cell bioengineering strategies to widen the therapeutic applications of haematopoietic stem/progenitor cells from umbilical cord blood.

artículo científico publicado en 2013

Stirred tank bioreactor culture combined with serum-/xenogeneic-free culture medium enables an efficient expansion of umbilical cord-derived mesenchymal stem/stromal cells.

artículo científico publicado en 2016

Successful isolation and ex vivo expansion of human mesenchymal stem/stromal cells obtained from different synovial tissue-derived (biopsy) samples

artículo científico publicado en 2018

Synergistic effect of extracellularly supplemented osteopontin and osteocalcin on stem cell proliferation, osteogenic differentiation, and angiogenic properties

artículo científico publicado en 2018

Systematic delineation of optimal cytokine concentrations to expand hematopoietic stem/progenitor cells in co-culture with mesenchymal stem cells

artículo científico publicado en 2010

Thermodynamics of the adsorption of monoclonal antibodies in phenylboronate chromatography: Affinity versus multimodal interactions

artículo científico publicado en 2018

Three-Dimensional Co-culture of Human Hematopoietic Stem/Progenitor Cells and Mesenchymal Stem/Stromal Cells in a Biomimetic Hematopoietic Niche Microenvironment

article

Tridimensional configurations of human mesenchymal stem/stromal cells to enhance cell paracrine potential towards wound healing processes.

artículo científico publicado en 2017

Lista de obras de

A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells.

A Stro-1(+) human universal stromal feeder layer to expand/maintain human bone marrow hematopoietic stem/progenitor cells in a serum-free culture system.

A human stromal-based serum-free culture system supports the ex vivo expansion/maintenance of bone marrow and cord blood hematopoietic stem/progenitor cells

A novel method for human hematopoietic stem/progenitor cell isolation from umbilical cord blood based on immunoaffinity aqueous two-phase partitioning

A xeno-free microcarrier-based stirred culture system for the scalable expansion of human mesenchymal stem/stromal cells isolated from bone marrow and adipose tissue.

A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells

Acellular Urethra Bioscaffold: Decellularization of Whole Urethras for Tissue Engineering Applications

Addressing the Manufacturing Challenges of Cell-Based Therapies

An appraisal of human mitochondrial DNA instability: new insights into the role of non-canonical DNA structures and sequence motifs.

Biomimetic matrices for rapidly forming mineralized bone tissue based on stem cell-mediated osteogenesis

Bioreactor design for clinical-grade expansion of stem cells.

Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin sulfate supplementation

Clinical-Grade Manufacturing of Therapeutic Human Mesenchymal Stem/Stromal Cells in Microcarrier-Based Culture Systems.

Co-culture cell-derived extracellular matrix loaded electrospun microfibrous scaffolds for bone tissue engineering

Concise review: Genomic instability in human stem cells: current status and future challenges.

Cultured cell-derived extracellular matrices to enhance the osteogenic differentiation and angiogenic properties of human mesenchymal stem/stromal cells

Developing a co-culture system for effective megakaryo/thrombopoiesis from umbilical cord blood hematopoietic stem/progenitor cells

Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics

Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia.

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage

Dynamic cell-cell interactions between cord blood haematopoietic progenitors and the cellular niche are essential for the expansion of CD34+, CD34+CD38- and early lymphoid CD7+ cells.

Engineering of Human Mesenchymal Stem/Stromal Cells with Vascular Endothelial Growth Factor-Encoding Minicircles for Angiogenic Ex Vivo Gene Therapy

Evaluation of gene delivery strategies to efficiently overexpress functional HLA-G on human bone marrow stromal cells

Ex vivo expansion of cord blood haematopoietic stem/progenitor cells under physiological oxygen tensions: clear-cut effects on cell proliferation, differentiation and metabolism.

Ex vivo expansion of human mesenchymal stem cells: a more effective cell proliferation kinetics and metabolism under hypoxia.

Extracellular matrix microarrays to study inductive signaling for endoderm specification

Extruded Bioreactor Perfusion Culture Supports the Chondrogenic Differentiation of Human Mesenchymal Stem/Stromal Cells in 3D Porous Poly(ɛ-Caprolactone) Scaffolds

Gelatin porous scaffolds fabricated using a modified gas foaming technique: characterisation and cytotoxicity assessment.

Gene delivery to human bone marrow mesenchymal stem cells by microporation.

Hematopoietic Niche - Exploring Biomimetic Cues to Improve the Functionality of Hematopoietic Stem/Progenitor Cells

Human mesenchymal stem cell expression program upon extended ex-vivo cultivation, as revealed by 2-DE-based quantitative proteomics.

Human mesenchymal stem cells from the umbilical cord matrix: successful isolation and ex vivo expansion using serum-/xeno-free culture media.

Impact of hypoxia and long-term cultivation on the genomic stability and mitochondrial performance of ex vivo expanded human stem/stromal cells

In vitro assessment of three dimensional dense chitosan-based structures to be used as bioabsorbable implants.

Initial CD34+ cell-enrichment of cord blood determines hematopoietic stem/progenitor cell yield upon ex vivo expansion.

Integrated culture platform based on a human platelet lysate supplement for the isolation and scalable manufacturing of umbilical cord matrix-derived mesenchymal stem/stromal cells.

Intracoronary Delivery of Human Mesenchymal/Stromal Stem Cells: Insights from Coronary Microcirculation Invasive Assessment in a Swine Model

Kinetic and metabolic analysis of mouse embryonic stem cell expansion under serum-free conditions.

Large-scale expansion of mouse embryonic stem cells on microcarriers.

Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells

Magnetoresistive chip cytometer.

Maximizing the ex vivo expansion of human mesenchymal stem cells using a microcarrier-based stirred culture system

Mesenchymal stem cells from umbilical cord matrix, adipose tissue and bone marrow exhibit different capability to suppress peripheral blood B, natural killer and T cells.

Microcarrier expansion of mouse embryonic stem cell-derived neural stem cells in stirred bioreactors.

Mobile-Phase Modulators as Salt Tolerance Enhancers in Phenylboronate Chromatography: Thermodynamic Evaluation of the Mechanisms Underlying the Adsorption of Monoclonal Antibodies

Modulation of the in vitro angiogenic potential of human mesenchymal stromal cells from different tissue sources

Monitoring the ex-vivo expansion of human mesenchymal stem/stromal cells in xeno-free microcarrier-based reactor systems by MIR spectroscopy

Oxazoline-based antimicrobial oligomers: synthesis by CROP using supercritical CO2.

Polyhydroxyalkanoates: waste glycerol upgrade into electrospun fibrous scaffolds for stem cells culture

Proliferation extent of CD34+ cells as a key parameter to maximize megakaryocytic differentiation of umbilical cord blood-derived hematopoietic stem/progenitor cells in a two-stage culture protocol

Scalable ex vivo expansion of human mesenchymal stem/stromal cells in microcarrier-based stirred culture systems.

Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells.

Scale-up of mouse embryonic stem cell expansion in stirred bioreactors.

Scaling up the ex vivo expansion of human circulating CD34(+)progenitor cells with upregulation of angiogenic and anti-inflammatory potential.

Separation technologies for stem cell bioprocessing.

Stem Cell Bioprocessing and Manufacturing

Stem cell bioengineering strategies to widen the therapeutic applications of haematopoietic stem/progenitor cells from umbilical cord blood.

Stirred tank bioreactor culture combined with serum-/xenogeneic-free culture medium enables an efficient expansion of umbilical cord-derived mesenchymal stem/stromal cells.

Successful isolation and ex vivo expansion of human mesenchymal stem/stromal cells obtained from different synovial tissue-derived (biopsy) samples

Synergistic effect of extracellularly supplemented osteopontin and osteocalcin on stem cell proliferation, osteogenic differentiation, and angiogenic properties

Systematic delineation of optimal cytokine concentrations to expand hematopoietic stem/progenitor cells in co-culture with mesenchymal stem cells

Thermodynamics of the adsorption of monoclonal antibodies in phenylboronate chromatography: Affinity versus multimodal interactions

Three-Dimensional Co-culture of Human Hematopoietic Stem/Progenitor Cells and Mesenchymal Stem/Stromal Cells in a Biomimetic Hematopoietic Niche Microenvironment

Tridimensional configurations of human mesenchymal stem/stromal cells to enhance cell paracrine potential towards wound healing processes.