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A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.

artículo científico publicado en 2011

CDK6 Antagonizes p53-Induced Responses during Tumorigenesis

article

CDK6 Inhibition: A Novel Approach in AML Management

scientific article published on 05 April 2020

CDK6 coordinates JAK2 V617F mutant MPN via NF-κB and apoptotic networks

scientific article published on 11 January 2019

Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis.

artículo científico publicado en 2009

Cdk6 contributes to cytoskeletal stability in erythroid cells.

artículo científico publicado en 2017

MEK inhibitors block growth of lung tumours with mutations in ataxia-telangiectasia mutated.

artículo científico publicado en 2016

PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis

artículo científico publicado en 2014

Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.

artículo científico publicado en 2016

STAT3: Versatile Functions in Non-Small Cell Lung Cancer

scientific article published on 29 April 2020

TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens

artículo científico publicado en 2014

Targeting KRAS Mutant Non-Small-Cell Lung Cancer: Past, Present and Future

scientific article published on 17 June 2020

Therapeutic Vulnerabilities in -Mutant AML Unmasked by Palbociclib

scientific article published on 11 December 2018

Ubiquitin-specific protease 4 inhibits mono-ubiquitination of the master growth factor signaling kinase PDK1

artículo científico publicado en 2012

p27 in FLT3-driven acute myeloid leukemia: many roads lead to ruin.

artículo científico publicado en 2017

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