Lista de obras -

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

artículo científico publicado en 2015

A homodimer model can resolve the conundrum as to how cytochrome P450 oxidoreductase and cytochrome b5 compete for the same binding site on cytochrome P450c17.

artículo científico publicado en 2016

A mechanism for the extension and unfolding of parallel G-quadruplexes by human telomerase at single-molecule resolution

artículo científico publicado en 2020

A structural view of PA2G4 isoforms with opposing functions in cancer

artículo científico publicado en 2020

A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development

artículo científico publicado en 2014

AMP and adenosine are both ligands for adenosine 2B receptor signaling.

artículo científico publicado en 2017

Amiloride is a competitive inhibitor of coxsackievirus B3 RNA polymerase

artículo científico publicado en 2011

An Activation-Specific Platelet Inhibitor That Can Be Turned On/Off by Medically Used Hypothermia

artículo científico publicado en 2011

Computational Analysis of Amiloride Analogue Inhibitors of Coxsackievirus B3 RNA Polymerase

artículo científico publicado en 2014

Control of Virulence Gene Expression by the Master Regulator, CfaD, in the Prototypical Enterotoxigenic Escherichia coli Strain, H10407.

artículo científico publicado en 2017

Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides.

artículo científico publicado en 2014

Direct involvement of the TEN domain at the active site of human telomerase

artículo científico publicado en 2010

Disarming bacterial virulence through chemical inhibition of the DNA binding domain of an AraC-like transcriptional activator protein.

artículo científico publicado en 2013

Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V

artículo científico publicado en 2011

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

scientific article published on 09 September 2019

Evolutionary comparisons predict that dimerization of human cytochrome P450 aromatase increases its enzymatic activity and efficiency

artículo científico publicado en 2015

Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers

artículo científico publicado en 2011

Identification of RNA-Binding Proteins as Targetable Putative Oncogenes in Neuroblastoma

scientific article published on 19 July 2020

Improvements, trends, and new ideas in molecular docking: 2012-2013 in review.

artículo científico

In vitro generation of neuraminidase inhibitor resistance in A(H5N1) influenza viruses.

artículo científico publicado en 2009

Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor.

artículo científico publicado en 2013

Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin

artículo científico publicado en 2012

Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).

artículo científico publicado en 2015

Molecular and structural insight into lysine selection on substrate and ubiquitin lysine 48 by the ubiquitin-conjugating enzyme Cdc34

scientific article published on 08 May 2013

Oncogenic protein interfaces: small molecules, big challenges.

artículo científico publicado en 2014

Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses.

artículo científico publicado en 2009

Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase

artículo científico publicado en 2010

Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation.

artículo científico publicado en 2013

Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster

artículo científico publicado en 2021

Sequence comparisons of cytochrome P450 aromatases from Australian animals predict differences in enzymatic activity and/or efficiency

scientific article published on 17 March 2020

Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity

artículo científico publicado en 2012

Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase.

artículo científico publicado en 2014

TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members

artículo científico publicado en 2012

The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA.

artículo científico publicado en 2016

Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2

artículo científico publicado en 2011

Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding.

artículo científico publicado en 2015

Zanamivir-resistant influenza viruses with a novel neuraminidase mutation

artículo científico publicado en 2009

Lista de obras de

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

A homodimer model can resolve the conundrum as to how cytochrome P450 oxidoreductase and cytochrome b5 compete for the same binding site on cytochrome P450c17.

A mechanism for the extension and unfolding of parallel G-quadruplexes by human telomerase at single-molecule resolution

A structural view of PA2G4 isoforms with opposing functions in cancer

A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development

AMP and adenosine are both ligands for adenosine 2B receptor signaling.

Amiloride is a competitive inhibitor of coxsackievirus B3 RNA polymerase

An Activation-Specific Platelet Inhibitor That Can Be Turned On/Off by Medically Used Hypothermia

Computational Analysis of Amiloride Analogue Inhibitors of Coxsackievirus B3 RNA Polymerase

Control of Virulence Gene Expression by the Master Regulator, CfaD, in the Prototypical Enterotoxigenic Escherichia coli Strain, H10407.

Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides.

Direct involvement of the TEN domain at the active site of human telomerase

Disarming bacterial virulence through chemical inhibition of the DNA binding domain of an AraC-like transcriptional activator protein.

Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

Evolutionary comparisons predict that dimerization of human cytochrome P450 aromatase increases its enzymatic activity and efficiency

Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers

Identification of RNA-Binding Proteins as Targetable Putative Oncogenes in Neuroblastoma

Improvements, trends, and new ideas in molecular docking: 2012-2013 in review.

In vitro generation of neuraminidase inhibitor resistance in A(H5N1) influenza viruses.

Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor.

Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin

Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).

Molecular and structural insight into lysine selection on substrate and ubiquitin lysine 48 by the ubiquitin-conjugating enzyme Cdc34

Oncogenic protein interfaces: small molecules, big challenges.

Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses.

Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase

Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation.

Role of nicotinic acetylcholine receptor subunits in the mode of action of neonicotinoid, sulfoximine and spinosyn insecticides in Drosophila melanogaster

Sequence comparisons of cytochrome P450 aromatases from Australian animals predict differences in enzymatic activity and/or efficiency

Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity

Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase.

TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members

The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA.

Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2

Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding.

Zanamivir-resistant influenza viruses with a novel neuraminidase mutation