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"Adiponectin paradox" and cancer risk: is it time for a re-evaluation of the beneficial effect of this adipokine?

artículo científico publicado en 2020

35th Annual Meeting of the European Association for the Study of Diabetes

artículo científico

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A Call to Action: Now Is the Time to Screen Elderly and Treat Osteosarcopenia, a Position Paper of the Italian College of Academic Nutritionists MED/49 (ICAN-49)

artículo científico publicado en 2020

A PC-1 amino acid variant (K121Q) is associated with faster progression of renal disease in patients with type 1 diabetes and albuminuria

artículo científico publicado en 2000

A cluster of three single nucleotide polymorphisms in the 3'-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities

artículo científico publicado en 2001

A functional variant of the adipocyte glycerol channel aquaporin 7 gene is associated with obesity and related metabolic abnormalities

artículo científico publicado en 2007

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance

artículo científico publicado en 1999

A soluble PC-1 circulates in human plasma: relationship with insulin resistance and associated abnormalities

artículo científico publicado en 1999

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

scientific article published on 06 February 2002

Abnormal 1-hour post-load glycemia during pregnancy impairs post-partum metabolic status: a single-center experience

artículo científico publicado en 2017

Adiponectin increases glucose-induced insulin secretion through the activation of lipid oxidation

artículo científico publicado en 2013

Adiponectin relationship with lipid metabolism is independent of body fat mass: evidence from both cross-sectional and intervention studies.

artículo científico publicado en 2004

Adipose Tissue, Obesity and Adiponectin: Role in Endocrine Cancer Risk

artículo científico publicado en 2019

An ATG repeat in the 3'-untranslated region of the human resistin gene is associated with a decreased risk of insulin resistance.

artículo científico publicado en 2002

Association between resistin levels and all-cause and cardiovascular mortality: a new study and a systematic review and meta-analysis

artículo científico publicado en 2015

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis

artículo científico publicado en 2000

Association of autoimmune thyroid diseases, chronic atrophic gastritis and gastric carcinoid: experience from a single institution

artículo científico publicado en 2016

Basal Insulin and Cardiovascular and Other Outcomes

artículo científico publicado en 2012

Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio

artículo científico publicado en 2001

Clinical and molecular mechanisms favoring cancer initiation and progression in diabetic patients.

artículo científico publicado en 2013

Correspondence between the International Diabetes Federation criteria for metabolic syndrome and insulin resistance in a cohort of Italian nondiabetic Caucasians: the GISIR database.

artículo científico publicado en 2007

Cytosolic and Calcium-Independent Phospholipases A2 Activation and Prostaglandins E2 Are Associated with Escherichia coli-Induced Reduction of Insulin Secretion in INS-1E Cells.

artículo científico publicado en 2016

ENPP1 Q121 Variant, Increased Pulse Pressure and Reduced Insulin Signaling, and Nitric Oxide Synthase Activity in Endothelial Cells

artículo científico publicado en 2009

ENPP1 affects insulin action and secretion: evidences from in vitro studies.

artículo científico publicado en 2011

ENPP1 mRNA levels in white blood cells and prediction of metformin efficacy in type 2 diabetic patients: A preliminary evidence

artículo científico publicado en 2011

Early molecular defects in human insulin resistance: studies in healthy subjects with low insulin sensitivity

artículo científico publicado en 1997

Efficacy of Botulinum Toxin A for Treating Cramps in Diabetic Neuropathy

artículo científico publicado en 2018

Efficacy of real-time continuous glucose monitoring on glycaemic control and glucose variability in type 1 diabetic patients treated with either insulin pumps or multiple insulin injection therapy: a randomized controlled crossover trial.

artículo científico publicado en 2015

Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects: evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signaling

artículo científico publicado en 1998

Elevated insulin receptor content in human breast cancer

artículo científico publicado en 1990

Evaluation of albumin excretion rate in overnight versus 24-h urine

scientific article published on 01 September 1989

Evidence for genetic epistasis in human insulin resistance: the combined effect of PC-1 (K121Q) and PPARgamma2 (P12A) polymorphisms

artículo científico publicado en 2003

Functional insulin receptors are overexpressed in thyroid tumors: is this an early event in thyroid tumorigenesis?

artículo científico publicado en 1999

High insulin levels do not influence PC-1 gene expression and protein content in human muscle tissue and hepatoma cells.

artículo científico publicado en 2000

High prevalence of overweight and obesity in 11-15-year-old children from Sicily

artículo científico publicado en 2006

Hyperinsulinemia and insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. The GISIR database

artículo científico publicado en 2007

Identification and initial characterization of insulin receptor-like immunoreactivity in human plasma

artículo científico publicado en 1992

Impact of unhealthy childhood and unfavorable parents' characteristics on adiposity in schoolchildren

artículo científico publicado en 2019

Implementation of a Personalized Care Plan for Patients With Type 2 Diabetes Is Associated With Improvements in Clinical Outcomes: An Observational Real-World Study

scientific article published on 01 January 2020

Increased adipose tissue PC-1 protein content, but not tumour necrosis factor-alpha gene expression, is associated with a reduction of both whole body insulin sensitivity and insulin receptor tyrosine-kinase activity

artículo científico publicado en 1997

Influence of early-life and parental factors on childhood overweight and obesity

artículo científico publicado en 2016

Influence of the Mediterranean and Ketogenic Diets on Cognitive Status and Decline: A Narrative Review

scientific article published on 08 April 2020

Insulin degludec in the first trimester of pregnancy: Report of two cases.

artículo científico publicado en 2017

Insulin receptor overexpression in 184B5 human mammary epithelial cells induces a ligand-dependent transformed phenotype

artículo científico publicado en 1995

Insulin receptor signaling and glucagon-like peptide 1 effects on pancreatic beta cells.

artículo científico publicado en 2017

Insulin receptor tyrosine kinase activity is reduced in monocytes from non-obese normoglycaemic insulin-resistant subjects

artículo científico publicado en 1993

Insulin receptor tyrosine-kinase activity is altered in both muscle and adipose tissue from non-obese normoglycaemic insulin-resistant subjects

artículo científico publicado en 1995

Insulin receptors in breast cancer.

artículo científico publicado en 1996

Insulin, insulin receptors, and cancer.

artículo científico publicado en 2016

Insulin/insulin-like growth factor I hybrid receptors overexpression is not an early defect in insulin-resistant subjects.

artículo científico publicado en 2000

Integrated insulin pump therapy with continuous glucose monitoring for improved adherence: technology update

artículo científico publicado en 2015

Intragastric balloon in association with lifestyle and/or pharmacotherapy in the long-term management of obesity

artículo científico publicado en 2012

Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance

artículo científico publicado en 2012

Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis.

artículo científico publicado en 2013

Long-acting insulin analogs and cancer.

artículo científico publicado en 2018

Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization

artículo científico publicado en 2008

Membrane glycoprotein PC-1 and insulin resistance.

artículo científico publicado en 1998

Obesity and cancer

artículo científico publicado en 2006

PC-1 content in skeletal muscle of non-obese, non-diabetic subjects: relationship to insulin receptor tyrosine kinase and whole body insulin sensitivity

artículo científico publicado en 1996

Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor

artículo científico publicado en 1995

Phenotyping normal kidney function in elderly patients with type 2 diabetes: a cross-sectional multicentre study

scientific article published on 09 August 2018

Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.

artículo científico publicado en 2003

Prevalence and Clinical Characteristics of Children and Adolescents with Metabolically Healthy Obesity: Role of Insulin Sensitivity

artículo científico publicado en 2020

Radioimmunoassay for human insulin-like growth factor-I receptor: applicability to breast carcinoma specimens and cell lines

artículo científico publicado en 1991

Rats that are made insulin resistant by glucosamine treatment have impaired skeletal muscle insulin receptor phosphorylation.

artículo científico publicado en 2003

Re: Insulin, insulin-like growth factor-I, and risk of breast cancer in postmenopausal women

artículo científico publicado en 2009

Relationship between insulin receptor tyrosine kinase activity and internalization in monocytes of non-insulin-dependent diabetes mellitus patients

artículo científico publicado en 1993

Role of PC-1 in the etiology of insulin resistance

artículo científico publicado en 1999

Role of cytosolic and calcium independent phospholipases A(2) in insulin secretion impairment of INS-1E cells infected by S. aureus

artículo científico publicado en 2015

Role of the ENPP1 K121Q polymorphism in glucose homeostasis.

artículo científico publicado en 2008

Secular trends in the prevalence of overweight and obesity in Sicilian schoolchildren aged 11-13 years during the last decade.

artículo científico publicado en 2012

Selective insulin receptor modulators (SIRM): a new class of antidiabetes drugs?

artículo científico publicado en 2012

Short-term adverse effects of anticancer drugs in patients with type 2 diabetes

scientific article published on 10 February 2019

Short-term efficacy of high intensity group and individual education in patients with type 2 diabetes: a randomized single-center trial

scientific article published on 10 August 2018

Strong evidence of sexual dimorphic effect of adiposity excess on insulin sensitivity

artículo científico publicado en 2015

Structural and functional studies of insulin receptors in human breast cancer

artículo científico publicado en 1993

TRIB3 R84 variant affects glucose homeostasis by altering the interplay between insulin sensitivity and secretion

artículo científico publicado en 2010

The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

artículo científico publicado en 2000

The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121)

artículo científico publicado en 2001

The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance

artículo científico publicado en 2001

The Q121/Q121 genotype of ENPP1/PC-1 is associated with lower BMI in non-diabetic whites

artículo científico publicado en 2007

The SH2B1 obesity locus and abnormal glucose homeostasis: lack of evidence for association from a meta-analysis in individuals of European ancestry.

artículo científico publicado en 2013

The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells

artículo científico publicado en 2011

The allelic variant of LAR gene promoter -127 bp T-->A is associated with reduced risk of obesity and other features related to insulin resistance

artículo científico publicado en 2004

The growing role of bariatric surgery in the management of type 2 diabetes: evidences and open questions.

artículo científico publicado en 2011

The insulin receptor content is increased in breast cancers initiated by three different oncogenes in transgenic mice.

artículo científico publicado en 1997

The intravenous insulin tolerance test is an accurate method for screening a general population for insulin resistance and related abnormalities

artículo científico publicado en 1999

The novel loss of function Ile354Val mutation in PPARG causes familial partial lipodystrophy

scientific article published on 20 December 2019

The prevalence of chronic kidney disease and screening of renal function in type 2 diabetic patients in Finnish primary healthcare

artículo científico publicado en 2020

The role of PC-1 and ACE genes in diabetic nephropathy in type 1 diabetic patients: evidence for a polygenic control of kidney disease progression

artículo científico publicado en 2002

The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities

artículo científico publicado en 2008

Type 2 Diabetes Mellitus and Alzheimer's Disease: Role of Insulin Signalling and Therapeutic Implications

article

Type 2 diabetic patients with Graves' disease have more frequent and severe Graves' orbitopathy.

artículo científico publicado en 2015

Very severely obese patients have a high prevalence of type 2 diabetes mellitus and cardiovascular disease

artículo científico publicado en 2013