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Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis.

artículo científico publicado en 2017

Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.

artículo científico publicado en 2018

Differential regulation of apoptosis by caspase-mediated cleavage of phospholipase D isozymes.

artículo científico publicado en 2008

H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development

artículo científico publicado en 2019

H3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability.

artículo científico publicado en 2016

HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

scientific article published on 27 September 2018

Histone H3 lysine 4 methyltransferase KMT2D.

artículo científico publicado en 2017

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis

artículo científico publicado en 2017

MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping

artículo científico publicado en 2017

N-Formyl-Methionyl-Leucyl-Phenylalanine (fMLP) Promotes Osteoblast Differentiation via the N-Formyl Peptide Receptor 1-mediated Signaling Pathway in Human Mesenchymal Stem Cells from Bone Marrow

artículo científico publicado el 3 de marzo de 2011

Nuclear localization of phospholipase D1 mediates the activation of nuclear protein kinase C(alpha) and extracellular signal-regulated kinase signaling pathways.

artículo científico publicado en 2010

Phospholipase D-mediated autophagic regulation is a potential target for cancer therapy.

artículo científico publicado en 2013

Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates

artículo científico publicado en 2014

Prognostic significance and function of phosphorylated ribosomal protein S6 in esophageal squamous cell carcinoma.

artículo científico publicado en 2012

Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF

scientific article published on 24 May 2019

Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease

artículo científico publicado en 2019

The hydrophobic amino acids involved in the interdomain association of phospholipase D1 regulate the shuttling of phospholipase D1 from vesicular organelles into the nucleus.

artículo científico publicado en 2012

Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells.

artículo científico publicado en 2009