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Absolute quantification of cell-bound DNA aptamers during SELEX.

artículo científico publicado en 2013

Application of a rotating bioreactor consisting of low-cost and ready-to-use medical disposables for in vitro evaluation of the endothelialization efficiency of small-caliber vascular prostheses

artículo científico publicado en 2013

Aptamers Influence the Hemostatic System by Activating the Intrinsic Coagulation Pathway in an In Vitro Chandler-Loop Model

artículo científico publicado en 2008

Blood-Contacting Biomaterials: In Vitro Evaluation of the Hemocompatibility.

artículo científico publicado en 2018

Cationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications.

artículo científico publicado en 2017

Concise Review: Application of In Vitro Transcribed Messenger RNA for Cellular Engineering and Reprogramming: Progress and Challenges

artículo científico publicado en 2016

Current Strategies and Future Perspectives of Skin-on-a-Chip Platforms: Innovations, Technical Challenges and Commercial Outlook

artículo científico publicado en 2018

Current concepts and new developments for autologous in vivo endothelialisation of biomaterials for intravascular applications

artículo científico publicado en 2011

De Novo Synthesis of Elastin by Exogenous Delivery of Synthetic Modified mRNA into Skin and Elastin-Deficient Cells.

artículo científico publicado en 2018

Development of hydrogels for regenerative engineering.

artículo científico publicado en 2017

Drug repurposing studies of PARP inhibitors as a new therapy for inherited retinal degeneration

artículo científico publicado en 2019

Efficient reduction of synthetic mRNA induced immune activation by simultaneous delivery of B18R encoding mRNA

scientific article published on 09 May 2019

Exogenous Delivery of Link N mRNA into Chondrocytes and MSCs-The Potential Role in Increasing Anabolic Response

artículo científico

Generation of Large-Scale DNA Hydrogels with Excellent Blood and Cell Compatibility.

artículo científico publicado en 2016

Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA

scientific article published on 19 June 2019

Generation of iPSCs from Jaw Periosteal Cells Using Self-Replicating RNA

scientific article published on 03 April 2019

Hemocompatibility of Axial Versus Centrifugal Pump Technology in Mechanical Circulatory Support Devices.

artículo científico publicado en 2015

Hemocompatibility testing according to ISO 10993-4: discrimination between pyrogen- and device-induced hemostatic activation

artículo científico publicado en 2014

Human Mesenchymal Stromal Cells from Different Sources Diverge in Their Expression of Cell Surface Proteins and Display Distinct Differentiation Patterns

artículo científico publicado en 2016

Importance of rigorous in vitro evaluation of prospective cell binding aptamers.

artículo científico

Improving the Angiogenic Potential of EPCs via Engineering with Synthetic Modified mRNAs

artículo científico publicado en 2018

In Vitro Evaluation of a Novel mRNA-Based Therapeutic Strategy for the Treatment of Patients Suffering from Alpha-1-Antitrypsin Deficiency.

artículo científico publicado en 2015

In vitro Study of a Novel Stent Coating Using Modified CD39 Messenger RNA to Potentially Reduce Stent Angioplasty-Associated Complications

artículo científico publicado en 2015

In vitro synthesis of modified mRNA for induction of protein expression in human cells

artículo científico publicado en 2014

In vitro test system for evaluation of immune activation potential of new single-stranded DNA-based therapeutics.

artículo científico publicado en 2014

In vivo tissue engineering: mimicry of homing factors for self-endothelialization of blood-contacting materials.

artículo científico publicado en 2013

Incorporation of Synthetic mRNA in Injectable Chitosan-Alginate Hybrid Hydrogels for Local and Sustained Expression of Exogenous Proteins in Cells.

artículo científico publicado en 2018

Induction of EPC homing on biofunctionalized vascular grafts for rapid in vivo self-endothelialization--a review of current strategies.

artículo científico publicado en 2010

Intradermal Delivery of Synthetic mRNA Using Hollow Microneedles for Efficient and Rapid Production of Exogenous Proteins in Skin.

artículo científico publicado en 2018

Microfluidic chip system for the selection and enrichment of cell binding aptamers

artículo científico publicado en 2015

New basic approach to treat non-small cell lung cancer based on RNA-interference

artículo científico publicado en 2014

New strategies for in vivo tissue engineering by mimicry of homing factors for self-endothelialisation of blood contacting materials.

scientific article published on 21 July 2008

One-staged aptamer-based isolation and application of endothelial progenitor cells in a porcine myocardial infarction model.

artículo científico publicado en 2014

Optimized conditions for successful transfection of human endothelial cells with in vitro synthesized and modified mRNA for induction of protein expression.

artículo científico publicado en 2014

Pitfalls of cell-systematic evolution of ligands by exponential enrichment (SELEX): existing dead cells during in vitro selection anticipate the enrichment of specific aptamers.

artículo científico publicado en 2010

Porcine EPCs downregulate stem cell markers and upregulate endothelial maturation markers during in vitro cultivation

scientific article published on 01 October 2009

Potential capacity of aptamers to trigger immune activation in human blood.

artículo científico publicado en 2013

Preclinical evaluation of the thrombogenicity and endothelialization of bare metal and surface-coated neurovascular stents.

artículo científico publicado en 2014

RNA-Eluting Surfaces for the Modulation of Gene Expression as A Novel Stent Concept.

artículo científico publicado en 2017

Rapid Complexation of Aptamers by Their Specific Antidotes.

artículo científico publicado en 2017

Reprogramming of Urine-Derived Renal Epithelial Cells into iPSCs Using srRNA and Consecutive Differentiation into Beating Cardiomyocytes

scientific article published on 31 July 2019

Selection and Application of Aptamers and Intramers.

artículo científico publicado en 2016

Small-interfering RNA-eluting surfaces as a novel concept for intravascular local gene silencing.

artículo científico publicado en 2011

Speeding up pyrogenicity testing: Identification of suitable cell components and readout parameters for an accelerated monocyte activation test (MAT).

artículo científico publicado en 2016

Streptavidin-coated magnetic beads for DNA strand separation implicate a multitude of problems during cell-SELEX.

artículo científico publicado en 2009

Upgrading SELEX technology by using lambda exonuclease digestion for single-stranded DNA generation

artículo científico publicado en 2009

Use of synthetic single-stranded oligonucleotides as artificial test soiling for validation of surgical instrument cleaning processes

artículo científico publicado en 2014