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Adenovirus Vector-Induced IL-6 Promotes Leaky Adenoviral Gene Expression, Leading to Acute Hepatotoxicity

artículo científico publicado en 2020

Cooperative regulation of mouse aldose reductase (AKR1B3) gene transcription by Nrf2, TonEBP, and c-jun

artículo científico publicado en 2019

Cranberry Attenuates Progression of Non-alcoholic Fatty Liver Disease Induced by High-Fat Diet in Mice

artículo científico publicado en 2019

Development of mice exhibiting hepatic microsomal activity of human CYP3A4 comparable to that in human liver microsomes by intravenous administration of an adenovirus vector expressing human CYP3A4.

artículo científico publicado en 2014

Evaluation of transduction properties of an adenovirus vector in neonatal mice.

artículo científico publicado en 2015

Further reduction in adenovirus vector-mediated liver transduction without largely affecting transgene expression in target organ by exploiting microrna-mediated regulation and the Cre-loxP recombination system

artículo científico publicado en 2012

Identification and characterization of functional antioxidant response elements in the promoter of the aldo-keto reductase AKR1B10 gene

artículo científico publicado en 2017

Suppression of leaky expression of adenovirus genes by insertion of microRNA-targeted sequences in the replication-incompetent adenovirus vector genome.

artículo científico publicado en 2014

Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.

artículo científico publicado en 2005

[Development of a Novel Method for the Treatment and Prevention of Diabetes Mellitus]

artículo científico publicado en 2019

[Development of a novel adenovirus vector exhibiting microRNA-mediated suppression of the leaky expression of adenovirus genes]

artículo científico publicado en 2012

[Obstacles and approaches to the development of gene therapy and nucleic acid-based drug]

artículo científico publicado en 2012

[The Investigation of Genes, Using an Improved Adenovirus Vector, and Food for the Treatment and Prevention of Type 2 Diabetes Mellitus]

artículo científico publicado en 2019

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