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A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system

artículo científico publicado en 2017

A versatile synthesis of unsymmetrical 3,3'-bioxindoles: stereoselective Mukaiyama aldol reactions of 2-siloxyindoles with isatins.

scientific article published on 15 October 2008

Asymmetric construction of rings A-D of daphnicyclidin-type alkaloids.

artículo científico publicado en 2009

Carboxamide Spleen Tyrosine Kinase (Syk) Inhibitors: Leveraging Ground State Interactions To Accelerate Optimization

artículo científico publicado en 2016

Current approaches to the treatment of Parkinson's Disease

artículo científico publicado en 2017

Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING

scientific article published on 06 December 2018

Establishing the absolute configuration of the asbestinins: enantioselective total synthesis of 11-acetoxy-4-deoxyasbestinin D

artículo científico publicado en 2005

Expedient access to saturated nitrogen heterocycles by photoredox cyclization of imino-tethered dihydropyridines

scientific article published on 28 August 2019

Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction.

artículo científico publicado en 2013

LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits

scientific article published on 01 April 2020

MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition.

artículo científico publicado en 2015

Overcoming mutagenicity and ion channel activity: optimization of selective spleen tyrosine kinase inhibitors.

artículo científico publicado en 2015

Strategy for Extending Half-life in Drug Design and Its Significance.

artículo científico publicado en 2018

Total synthesis of brevetoxin A

artículo científico publicado en 2009

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