Filtros de búsqueda

Lista de obras de

Acidic biphenyl derivatives: synthesis and biological activity of a new series of potent 5-HT(4) receptor antagonists

artículo científico publicado en 2013

Activation of adenylyl cyclase by endogenous G(s)-coupled receptors in human embryonic kidney 293 cells is attenuated by 5-HT(7) receptor expression.

artículo científico publicado en 2005

An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling

artículo científico publicado en 2020

Brain penetrant small molecule (18)F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats.

artículo científico publicado en 2016

Construction of novel cGMP FRET-sensors based on PKG from Plasmodium falciparum.

artículo científico publicado en 2015

Discovery and pharmacological profile of new hydrophilic 5-HT(4) receptor antagonists.

artículo científico publicado en 2014

Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6.

artículo científico publicado en 2014

FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons

scientific article published on 29 October 2019

Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor.

artículo científico publicado en 2006

Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis

artículo científico publicado en 2015

Preassociation between the 5-HT7 serotonin receptor and G protein Gs: molecular determinants and association with low potency activation of adenylyl cyclase

scientific article published on 03 December 2018

Related GPCRs couple differently to Gs: preassociation between G protein and 5-HT7 serotonin receptor reveals movement of Gαs upon receptor activation.

artículo científico publicado en 2017

Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function

scientific journal article

Synthesis and in vitro evaluation of small-molecule [18F] labeled gonadotropin-releasing hormone (GnRH) receptor antagonists as potential PET imaging agents for GnRH receptor expression.

artículo científico publicado en 2014

The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7 receptors.

artículo científico publicado en 2015

The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium

artículo científico publicado en 2015

The serotonin 5-HT7 receptors: two decades of research

artículo científico publicado en 2013

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda