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3,4-Methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition

artículo científico publicado el 22 de marzo de 2011

A mechanistic insight into 3,4-methylenedioxymethamphetamine ("ecstasy")-mediated hepatotoxicity.

artículo científico publicado en 2011

A new highly specific and robust yeast androgen bioassay for the detection of agonists and antagonists

artículo científico publicado en 2007

Activation of the aryl hydrocarbon receptor reduces the number of precursor and effector T cells, but preserves thymic CD4+CD25+Foxp3+ regulatory T cells

artículo científico publicado en 2012

Activation of the aryl hydrocarbon receptor suppresses sensitization in a mouse peanut allergy model.

artículo científico publicado en 2011

Androgen Receptor Expression in Thai Breast Cancer Patients

artículo científico publicado en 2016

Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts.

artículo científico publicado en 2014

Anti-tumor properties of methoxylated analogues of resveratrol in malignant MCF-7 but not in non-tumorigenic MCF-10A mammary epithelial cell lines

scientific article published on 18 April 2019

Aryl hydrocarbon receptor activation affects the dendritic cell phenotype and function during allergic sensitization

scientific article published on 01 February 2013

Chemopreventive actions by enterolactone and 13 VIOXX-related lactone derivatives in H295R human adrenocortical carcinoma cells.

artículo científico publicado en 2009

Comparison of Intake and Systemic Relative Effect Potencies of Dioxin-like Compounds in Female Mice after a Single Oral Dose

artículo científico publicado el 3 de mayo de 2013

Comparison of intake and systemic relative effect potencies of dioxin-like compounds in female rats after a single oral dose

artículo científico publicado en 2013

Consensus toxicity factors for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls combining in silico models and extensive in vitro screening of AhR-mediated effects in human and rodent cells

artículo científico publicado en 2015

Corrigendum to "Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro" [Toxicol. Rep. 1C (2014) 271-283]

scientific article published on 09 December 2016

Cytochrome P450 1A1 and 1B1 in human blood lymphocytes are not suitable as biomarkers of exposure to dioxin-like compounds: polymorphisms and interindividual variation in expression and inducibility.

artículo científico publicado en 2005

Depsidones inhibit aromatase activity and tumor cell proliferation in a co-culture of human primary breast adipose fibroblasts and T47D breast tumor cells

artículo científico publicado en 2017

Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells.

artículo científico publicado en 2014

Differential roles of phase I and phase II enzymes in 3,4-methylendioxymethamphetamine-induced cytotoxicity.

artículo científico publicado en 2010

Effect of androgens on different breast cancer cells co-cultured with or without breast adipose fibroblasts.

artículo científico publicado en 2013

Endocrine disruptors differentially target ATP-binding cassette transporters in the blood-testis barrier and affect Leydig cell testosterone secretion in vitro.

artículo científico publicado en 2013

Evaluation of an alternative in vitro test battery for detecting reproductive toxicants

artículo científico publicado el 16 de marzo de 2013

Evaluation of anti-tumour properties of two depsidones - Unguinol and Aspergillusidone D - in triple-negative MDA-MB-231 breast tumour cells

scientific article published on 20 October 2019

Excessive levels of diverse phytoestrogens can modulate steroidogenesis and cell migration of KGN human granulosa-derived tumor cells.

artículo científico publicado en 2014

GH3 and RC-4BC cell lines are not suitable as in vitro models to study prolactin modulation and AHR responsiveness in rat pituitary

artículo científico publicado en 2019

Genistein induces breast cancer-associated aromatase and stimulates estrogen-dependent tumor cell growth in in vitro breast cancer model.

artículo científico publicado en 2011

Imatinib mesylate does not counteract ovarian tissue fibrosis in postnatal rat ovary

scientific article published on 10 May 2019

In vitro and in silico derived relative effect potencies of ah-receptor-mediated effects by PCDD/Fs and PCBs in rat, mouse, and guinea pig CALUX cell lines.

artículo científico publicado en 2014

In vitro neuroendocrine effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the AhR-expressing hypothalamic rat GnV-3 cell line.

artículo científico publicado en 2013

Induction of cell cycle arrest in human MCF-7 breast cancer cells by cis-stilbene derivatives related to VIOXX.

artículo científico publicado en 2009

Induction of glutathione synthesis and conjugation by 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-dihydroxymethamphetamine (HHMA) in human and rat liver cells, including the protective role of some antioxidants

artículo científico publicado el 17 de agosto de 2011

Inter-laboratory comparison of a yeast bioassay for the determination of estrogenic activity in biological samples.

artículo científico publicado en 2008

Modulation of estrogen synthesis and metabolism by phytoestrogens in vitro and the implications for women's health

scientific article published on 08 September 2017

Naringenin (NAR) and 8-prenylnaringenin (8-PN) reduce the developmental competence of porcine oocytes in vitro.

artículo científico publicado en 2014

No effect of CYP1B1 Val432Leu polymorphism on CYP1B1 messenger RNA levels in an organochlorine-exposed population in Slovakia

artículo científico publicado en 2005

Non-dioxin-like AhR ligands in a mouse peanut allergy model.

artículo científico publicado en 2012

Phytoestrogens in menopausal supplements induce ER-dependent cell proliferation and overcome breast cancer treatment in an in vitro breast cancer model.

artículo científico publicado en 2013

Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers.

artículo científico publicado en 2018

Primary endometrial 3D co-cultures: A comparison between human and rat endometrium

scientific article published on 26 August 2019

Putative adverse outcome pathways for female reproductive disorders to improve testing and regulation of chemicals

artículo científico publicado en 2020

Relative effective potencies of dioxin-like compounds in rodent and human lung cell models

artículo científico publicado en 2018

Safeguarding Female Reproductive Health against Endocrine Disrupting Chemicals-The FREIA Project

artículo científico publicado en 2020

Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO2-PCBs

artículo científico publicado el 12 de julio de 2011

Specific in vitro toxicity of crude and refined petroleum products: 3. Estrogenic responses in mammalian assays.

artículo científico publicado en 2011

Specific in vitro toxicity of crude and refined petroleum products: II. Estrogen (alpha and beta) and androgen receptor-mediated responses in yeast assays.

artículo científico publicado en 2010

The relevance of chemical interactions with CYP17 enzyme activity: assessment using a novel in vitro assay.

artículo científico publicado en 2013