Lista de obras -

A 96-well flow cytometric screening assay for detecting in vitro phospholipidosis-induction in the drug discovery phase.

artículo científico publicado en 2008

A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand

artículo científico publicado en 2003

A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions

artículo científico publicado en 2007

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

artículo científico publicado en 2018

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

artículo científico publicado en 2011

A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection

artículo científico publicado en 2012

A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

artículo científico publicado en 2016

A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes

artículo científico publicado en 2015

A20 Restrains Thymic Regulatory T Cell Development.

artículo científico publicado en 2017

A20 and CYLD do not share significant overlapping functions during B cell development and activation

artículo científico publicado en 2012

A20 and Cell Death-driven Inflammation

scientific article published on 30 March 2020

A20 at the Crossroads of Cell Death, Inflammation, and Autoimmunity

scientific article published on 02 January 2020

A20 controls intestinal homeostasis through cell-specific activities

artículo científico publicado en 2014

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.

artículo científico publicado en 2018

A20 deletion in T cells modulates acute graft-versus-host disease in mice

artículo científico publicado en 2017

A20 in inflammation and autoimmunity

artículo científico publicado en 2013

A20 inhibition of STAT1 expression in myeloid cells: a novel endogenous regulatory mechanism preventing development of enthesitis

artículo científico publicado en 2016

A20 phosphorylation controls A20 function

scientific article published on 01 October 2019

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

scientific article published on 13 May 2019

A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1.

artículo científico publicado en 2017

A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

artículo científico publicado en 2019

A20-deficient mast cells exacerbate inflammatory responses in vivo

artículo científico publicado en 2014

A20: attractive without showing cleavage

artículo científico publicado en 2014

ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation

artículo científico publicado en 2022

ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway

artículo científico publicado en 2022

Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis

scientific article published on 13 January 2017

Adipose tissue macrophages and their polarization in health and obesity

artículo científico publicado en 2018

An Unusual Location of Extraosseous Ewing's Sarcoma ⬇️

artículo científico publicado el 30 de mayo de 2013

Antiinflammatory Properties of a Plant-Derived Nonsteroidal, Dissociated Glucocorticoid Receptor Modulator in Experimental Autoimmune Encephalomyelitis.

artículo científico publicado en 2009

Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis

artículo científico publicado en 2009

Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1.

artículo científico publicado en 2005

Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.

artículo científico publicado en 2018

Author Correction: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

scientific article published on 01 April 2019

Author Correction: Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes

artículo científico publicado en 2022

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

scientific journal article

BACE2 distribution in major brain cell types and identification of novel substrates

scientific article published on 01 January 2018

Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death

artículo científico publicado en 2004

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

artículo científico publicado en 2012

Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans Hyphae

artículo científico publicado en 2019

Cellular Functions of Optineurin in Health and Disease

artículo científico publicado en 2016

Conditional targeting of tumor necrosis factor receptor-associated factor 6 reveals opposing functions of Toll-like receptor signaling in endothelial and myeloid cells in a mouse model of atherosclerosis

artículo científico publicado en 2012

Correction: A20 () Deficiency in Myeloid Cells Protects against Influenza A Virus Infection

Correction: A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

artículo científico publicado en 2020

DNGR1-Cre-mediated Deletion of Tnfaip3/A20 in Conventional Dendritic Cells Induces Pulmonary Hypertension in Mice

artículo científico publicado en 2020

DNGR1-mediated deletion of A20/Tnfaip3 in dendritic cells alters T and B-cell homeostasis and promotes autoimmune liver pathology

scientific article published on 09 July 2019

Death receptor signalling in central nervous system inflammation and demyelination

artículo científico publicado en 2011

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

artículo científico publicado en 2007

Development of a sanitary risk index for Salmonella seroprevalence in Belgian pig farms.

artículo científico publicado en 2008

Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals

scientific article published on 03 May 2009

Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.

artículo científico publicado en 2003

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

artículo científico publicado en 2002

El Tor Biotype Vibrio cholerae Activates the Caspase-11-Independent Canonical Nlrp3 and Pyrin Inflammasomes

artículo científico publicado en 2019

Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway

artículo científico publicado en 2012

Enterocyte death and intestinal barrier maintenance in homeostasis and disease

artículo científico publicado en 2011

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

artículo científico publicado en 2010

Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation

scientific article published on 01 November 2019

Epithelial NEMO links innate immunity to chronic intestinal inflammation

artículo científico publicado en 2007

Expression, biological activities and mechanisms of action of A20 (TNFAIP3).

artículo científico publicado en 2010

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

artículo científico publicado en 2011

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

artículo científico publicado en 2015

Fibrotic enzymes modulate wound-induced skin tumorigenesis

artículo científico publicado en 2021

Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease

artículo científico publicado en 2011

Hepatic tumor necrosis factor signaling and nuclear factor-kappaB: effects on liver homeostasis and beyond.

artículo científico publicado en 2007

House dust mite-driven neutrophilic airway inflammation in mice with TNFAIP3-deficient myeloid cells is IL-17-independent

artículo científico publicado en 2018

IL1β promotes immune suppression in the tumor microenvironment independent of the inflammasome and gasdermin

scientific article published on 23 December 2020

Identification of Immune-Responsive Gene 1 (IRG1) as a Target of A20

artículo científico publicado en 2018

Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

artículo científico publicado en 2008

IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system

artículo científico publicado en 2011

Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients

artículo científico publicado en 2020

Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors

artículo científico publicado en 2005

Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease

artículo científico publicado en 2024

Inflammasomes in neuroinflammatory and neurodegenerative diseases.

artículo científico publicado en 2019

Inflammation and the Metabolic Syndrome: The Tissue-Specific Functions of NF-κB.

artículo científico publicado en 2017

Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice

scholarly article by Geert van Loo et al published 6 August 2006 in Nature Immunology

Keratinocyte Expression of A20/TNFAIP3 Controls Skin Inflammation Associated with Atopic Dermatitis and Psoriasis

artículo científico publicado en 2018

Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

artículo científico publicado en 2014

MicroRNA let-7 modulates the immune response to Mycobacterium tuberculosis infection via control of A20, an inhibitor of the NF-κB pathway.

artículo científico publicado en 2015

Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology

artículo científico publicado en 2018

Mitochondrial intermembrane proteins in cell death

artículo científico publicado en 2003

NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes

artículo científico publicado en 2022

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.

artículo científico publicado en 2016

Negative regulation of NF-κB and its involvement in rheumatoid arthritis

artículo científico publicado en 2011

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

artículo científico publicado en 2014

Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection

artículo científico publicado en 2019

Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology

artículo científico

Nucleic Acid Induced Interferon and Inflammasome Responses in Regulating Host Defense to Gastrointestinal Viruses

scientific article published on 03 October 2018

OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis

artículo científico publicado en 2020

Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination

artículo científico publicado en 2010

Optineurin Functions for Optimal Immunity

artículo científico publicado en 2018

Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling

artículo científico publicado en 2015

Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination

artículo científico publicado en 2013

Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis.

artículo científico publicado en 2014

Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis

scientific article published on 23 April 2019

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

artículo científico publicado en 2014

Regulation of macrophage motility by the water channel aquaporin-1: crucial role of M0/M2 phenotype switch

artículo científico publicado en 2015

Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas.

artículo científico publicado en 2002

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

artículo científico publicado en 2019

TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

artículo científico publicado en 2015

TNF-α-induced protein 3 levels in lung dendritic cells instruct TH2 or TH17 cell differentiation in eosinophilic or neutrophilic asthma

artículo científico publicado en 2017

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes

artículo científico publicado en 2022

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

artículo científico publicado en 2011

The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine

artículo científico publicado en 2016

The anti-inflammatory protein TNFAIP3/A20 binds the WD40 domain of ATG16L1 to control the autophagic response, NFKB/NF-κB activation and intestinal homeostasis

scientific article published on 16 June 2019

The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells

artículo científico publicado en 2014

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

artículo científico publicado en 2009

The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF

artículo científico publicado en 2019

The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.

artículo científico publicado en 2011

Tnfaip3 expression in pulmonary conventional type 1 Langerin-expressing dendritic cells regulates T helper 2-mediated airway inflammation in mice

scientific article published on 23 April 2020

Toxic proteins released from mitochondria in cell death

artículo científico publicado en 2004

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

artículo científico publicado en 2020

ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation

artículo científico publicado en 2021

Lista de obras de

A 96-well flow cytometric screening assay for detecting in vitro phospholipidosis-induction in the drug discovery phase.

A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand

A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection

A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection

A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes

A20 Restrains Thymic Regulatory T Cell Development.

A20 and CYLD do not share significant overlapping functions during B cell development and activation

A20 and Cell Death-driven Inflammation

A20 at the Crossroads of Cell Death, Inflammation, and Autoimmunity

A20 controls intestinal homeostasis through cell-specific activities

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.

A20 deletion in T cells modulates acute graft-versus-host disease in mice

A20 in inflammation and autoimmunity

A20 inhibition of STAT1 expression in myeloid cells: a novel endogenous regulatory mechanism preventing development of enthesitis

A20 phosphorylation controls A20 function

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1.

A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

A20-deficient mast cells exacerbate inflammatory responses in vivo

A20: attractive without showing cleavage

ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation

ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway

Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis

Adipose tissue macrophages and their polarization in health and obesity

An Unusual Location of Extraosseous Ewing's Sarcoma ⬇️

Antiinflammatory Properties of a Plant-Derived Nonsteroidal, Dissociated Glucocorticoid Receptor Modulator in Experimental Autoimmune Encephalomyelitis.

Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis

Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1.

Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.

Author Correction: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

Author Correction: Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

BACE2 distribution in major brain cell types and identification of novel substrates

Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans Hyphae

Cellular Functions of Optineurin in Health and Disease

Conditional targeting of tumor necrosis factor receptor-associated factor 6 reveals opposing functions of Toll-like receptor signaling in endothelial and myeloid cells in a mouse model of atherosclerosis

Correction: A20 () Deficiency in Myeloid Cells Protects against Influenza A Virus Infection

Correction: A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

DNGR1-Cre-mediated Deletion of Tnfaip3/A20 in Conventional Dendritic Cells Induces Pulmonary Hypertension in Mice

DNGR1-mediated deletion of A20/Tnfaip3 in dendritic cells alters T and B-cell homeostasis and promotes autoimmune liver pathology

Death receptor signalling in central nervous system inflammation and demyelination

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

Development of a sanitary risk index for Salmonella seroprevalence in Belgian pig farms.

Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals

Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

El Tor Biotype Vibrio cholerae Activates the Caspase-11-Independent Canonical Nlrp3 and Pyrin Inflammasomes

Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway

Enterocyte death and intestinal barrier maintenance in homeostasis and disease

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation

Epithelial NEMO links innate immunity to chronic intestinal inflammation

Expression, biological activities and mechanisms of action of A20 (TNFAIP3).

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

Fibrotic enzymes modulate wound-induced skin tumorigenesis

Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease

Hepatic tumor necrosis factor signaling and nuclear factor-kappaB: effects on liver homeostasis and beyond.

House dust mite-driven neutrophilic airway inflammation in mice with TNFAIP3-deficient myeloid cells is IL-17-independent

IL1β promotes immune suppression in the tumor microenvironment independent of the inflammasome and gasdermin

Identification of Immune-Responsive Gene 1 (IRG1) as a Target of A20

Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system

Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients

Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors

Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease

Inflammasomes in neuroinflammatory and neurodegenerative diseases.

Inflammation and the Metabolic Syndrome: The Tissue-Specific Functions of NF-κB.

Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice

Keratinocyte Expression of A20/TNFAIP3 Controls Skin Inflammation Associated with Atopic Dermatitis and Psoriasis

Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

MicroRNA let-7 modulates the immune response to Mycobacterium tuberculosis infection via control of A20, an inhibitor of the NF-κB pathway.

Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology

Mitochondrial intermembrane proteins in cell death