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A Sensitive and Selective Immunoassay for the Quantitation of Serum Latent Myostatin after In Vivo Administration of SRK-015, a Selective Inhibitor of Myostatin Activation

artículo científico publicado en 2019

Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Non-Human Primates of the Anti-PD-1 Antibody Pembrolizumab

artículo científico publicado en 2020

Blocking extracellular activation of myostatin as a strategy for treating muscle wasting

artículo científico publicado en 2018

Characterization of binding mode of action of a blocking anti-platelet-derived growth factor (PDGF)-B monoclonal antibody, MOR8457, reveals conformational flexibility and avidity needed for PDGF-BB to bind PDGF receptor-β

artículo científico publicado en 2015

Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design

artículo científico publicado en 2020

PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancer

article

Probing the ligand-induced conformational change in HLA-DR1 by selective chemical modification and mass spectrometric mapping.

artículo científico publicado en 2005

Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape

artículo científico publicado en 2020

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