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A patient-derived xenograft mouse model generated from primary cultured cells recapitulates patient tumors phenotypically and genetically.

artículo científico publicado en 2013

Analysis and comparison of somatic mutations in paired primary and recurrent epithelial ovarian cancer samples

artículo científico publicado en 2014

Association between the CpG island methylator phenotype and its prognostic significance in primary pulmonary adenocarcinoma.

artículo científico publicado en 2016

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency

artículo científico publicado en 2013

Comparison of genetic and epigenetic alterations at 11 tumor suppressor loci in pulmonary sclerosing hemangioma and adenocarcinoma

artículo científico publicado en 2011

Deregulated expression of microRNA-221 with the potential for prognostic biomarkers in surgically resected hepatocellular carcinoma.

artículo científico publicado en 2011

Detection of chromosome structural variation by targeted next-generation sequencing and a deep learning application

artículo científico publicado en 2019

Development and characterization of a colon PDX model that reproduces drug responsiveness and the mutation profiles of its original tumor.

artículo científico publicado en 2013

Epigenetic modulation with HDAC inhibitor CG200745 induces anti-proliferation in non-small cell lung cancer cells

artículo científico publicado en 2015

Epigenetic silencing of microRNA-373 to epithelial-mesenchymal transition in non-small cell lung cancer through IRAK2 and LAMP1 axes

artículo científico publicado en 2014

Feasibility of multiplexed gene mutation detection in plasma samples of colorectal cancer patients by mass spectrometric genotyping

artículo científico publicado en 2017

Genomic Alterations in the RB Pathway Indicate Prognostic Outcomes of Early-Stage Lung Adenocarcinoma

scientific article published on 07 October 2014

Genomic profiles of lung cancer associated with idiopathic pulmonary fibrosis.

artículo científico publicado en 2017

Genotyping of CYP21A2 for congenital adrenal hyperplasia screening using allele-specific primer extension followed by bead array hybridization.

artículo científico publicado en 2009

Good Laboratory Standards for Clinical Next-Generation Sequencing Cancer Panel Tests.

artículo científico publicado en 2017

HER2 Amplification and Cetuximab Efficacy in Patients With Metastatic Colorectal Cancer Harboring Wild-type RAS and BRAF.

artículo científico publicado en 2017

High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases.

artículo científico publicado en 2013

Hypermethylation of adjacent CpG sites is negatively correlated with the expression of lineage oncogene ASCL1 in pulmonary neuroendocrine tumors

artículo científico publicado en 2017

Immunogenomic landscape of hepatocellular carcinoma with immune cell stroma and EBV-positive tumor-infiltrating lymphocytes

scientific article published on 29 March 2019

KRAS and PIK3CA mutations in colorectal adenocarcinomas correlate with aggressive histological features and behavior.

artículo científico publicado en 2017

Lynch syndrome-related small intestinal adenocarcinomas.

artículo científico publicado en 2017

Mechanisms of acquired resistance to EGFR-tyrosine kinase inhibitor in Korean patients with lung cancer.

artículo científico publicado en 2013

Multiple resistant factors in lung cancer with primary resistance to EGFR-TK inhibitors confer poor survival.

artículo científico publicado en 2015

Mutation burden and I index for Detection of microsatellite instability in colorectal cancer by targeted next-generation sequencing

artículo científico publicado en 2018

Mutational Profiling of Malignant Mesothelioma Revealed Potential Therapeutic Targets in EGFR and NRAS.

artículo científico publicado en 2018

Mutational profile of papillary thyroid microcarcinoma with extensive lymph node metastasis

artículo científico publicado en 2019

Next-Generation Sequencing Using S1 Nuclease for Poor-Quality Formalin-Fixed, Paraffin-Embedded Tumor Specimens

artículo científico publicado en 2018

Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer.

scientific article published on 04 July 2016

Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening

scientific article published on 05 September 2019

Prediction of Core Signaling Pathway by Using Diffusion- and Perfusion-based MRI Radiomics and Next-generation Sequencing in Isocitrate Dehydrogenase Wild-type Glioblastoma

scientific article published on 17 December 2019

Promoter methylation of WNT inhibitory factor-1 and expression pattern of WNT/β-catenin pathway in human astrocytoma: pathologic and prognostic correlations.

artículo científico publicado en 2013

Protuberant fibro-osseous lesions of the temporal bone: two additional case reports.

artículo científico publicado en 2014

Reappraisal of hMLH1 promoter methylation and protein expression status in the serrated neoplasia pathway

artículo científico publicado en 2016

Sessile serrated adenoma/polyps with a depressed surface: a rare form of sessile serrated adenoma/polyp.

artículo científico publicado en 2015

The significance of ectopic crypt formation in the differential diagnosis of colorectal polyps.

artículo científico publicado en 2014

The somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy.

artículo científico publicado en 2016

TotalPlex gene amplification using bulging primers for pharmacogenetic analysis of acute lymphoblastic leukemia.

artículo científico publicado en 2008

Traditional serrated adenoma of the colorectum: clinicopathologic implications and endoscopic findings of the precursor lesions

artículo científico publicado en 2013

Use of a High-Throughput Genotyping Platform (OncoMap) for RAS Mutational Analysis to Predict Cetuximab Efficacy in Patients with Metastatic Colorectal Cancer.

artículo científico publicado en 2016