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A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.

artículo científico publicado en 2011

A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants

artículo científico publicado en 2021

CUEDC2 interacts with heat shock protein 70 and negatively regulates its chaperone activity

scientific article published on 28 March 2014

Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1.

artículo científico publicado en 2008

Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population.

artículo científico publicado en 2012

IKKα negatively regulates ASC-dependent inflammasome activation

artículo científico publicado en 2014

IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression

artículo científico publicado en 2017

IL-17-induced Act1-mediated signaling is critical for cuprizone-induced demyelination

artículo científico publicado en 2012

IL-37 Represses the Autoimmunity in Myasthenia Gravis via Directly Targeting Follicular Th and B Cells

scientific article published on 28 February 2020

Oncolytic Zika virus promotes intratumoral T cell infiltration and improves immunotherapy efficacy in glioblastoma

artículo científico publicado en 2022

RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis

artículo científico publicado en 2020

T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis

artículo científico publicado en 2016

TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response

artículo científico publicado en 2020

TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation

article

The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling

artículo científico publicado en 2014

The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo.

artículo científico publicado en 2017

Tumor-targeted delivery of biologically active TRAIL protein.

artículo científico publicado en 2010