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A rapid and sensitive automated image-based approach for in vitro and in vivo characterization of cell morphology and quantification of cell number and neurite architecture

artículo científico publicado en 2014

ABCA1 Deficiency Affects Basal Cognitive Deficits and Dendritic Density in Mice.

artículo científico publicado en 2017

Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease

artículo científico publicado en 2022

Automated imaging system for fast quantitation of neurons, cell morphology and neurite morphometry in vivo and in vitro.

artículo científico publicado en 2012

Behavioral, neurochemical, and pathologic alterations in bacterial artificial chromosome transgenic G2019S leucine-rich repeated kinase 2 rats

artículo científico publicado en 2014

Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy

artículo científico publicado en 2018

Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies

artículo científico publicado en 2013

Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment.

artículo científico publicado en 2012

Identification of an inducible nitric oxide synthase in diaphragm mitochondria from septic mice: its relation with mitochondrial dysfunction and prevention by melatonin.

artículo científico publicado en 2005

Impact of the Sensory Neurons on Melanoma Growth In Vivo

artículo científico publicado en 2016

Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice.

artículo científico publicado en 2009

Melatonin counteracts inducible mitochondrial nitric oxide synthase-dependent mitochondrial dysfunction in skeletal muscle of septic mice.

artículo científico publicado en 2006

Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model.

artículo científico publicado en 2010

Mitochondrial Complex I Reversible S-Nitrosation Improves Bioenergetics and Is Protective in Parkinson's Disease.

artículo científico publicado en 2017

Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.

artículo científico publicado en 2015

Phenothiazine normalizes the NADH/NAD ratio, maintains mitochondrial integrity and protects the nigrostriatal dopamine system in a chronic rotenone model of Parkinson's disease

article

Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors.

artículo científico publicado en 2008

Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson's disease

artículo científico publicado en 2013

Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

artículo científico publicado en 2011

Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III).

artículo científico publicado en 2008

Resveratrol and pinostilbene confer neuroprotection against aging-related deficits through an ERK1/2-dependent mechanism.

artículo científico publicado en 2017

Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production

artículo científico publicado en 2017

shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model

artículo científico publicado en 2015