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Bicyclic peptides conjugated to an albumin-binding tag diffuse efficiently into solid tumors.

artículo científico publicado en 2014

Bicyclization and tethering to albumin yields long-acting peptide antagonists.

artículo científico publicado en 2012

Boosting the Sensitivity of Ligand–Protein Screening by NMR of Long-Lived States

scientific article published on 27 June 2012

Chemical Macrocyclization of Peptides Fused to Antibody Fc Fragments

artículo científico publicado en 2012

Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis.

artículo científico publicado en 2018

Enzymatic cyclisation of peptides with a transglutaminase.

artículo científico publicado en 2011

Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses

artículo científico publicado en 2017

Measuring net protease activities in biological samples using selective peptidic inhibitors.

artículo científico publicado en 2012

Molecular evolution of peptides by yeast surface display technology

scientific article published on 10 July 2019

Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics

scientific article published on 06 June 2019

Peptide ligands stabilized by small molecules

artículo científico publicado en 2014

Post-translational modification of genetically encoded polypeptide libraries.

artículo científico publicado en 2011

Protein Engineering and Selection Using Yeast Surface Display.

artículo científico publicado en 2015

Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines

artículo científico publicado en 2013

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

artículo científico publicado en 2015

Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides.

artículo científico publicado en 2012

Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.

artículo científico publicado en 2015

The crystal structure of CagS from theHelicobacter pyloripathogenicity island

scientific article published on 01 November 2007

Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands

scientific article published on 21 August 2019

Triggering positive selection of germinal center B cells by antigen targeting to DEC-205

artículo científico publicado en 2015